Comparing Fertility Rates of Fresh Versus Frozen Embryo Transfer in Antagonist IVF Cycles
Abstract Purpose The purpose of this retrospective cohort study was to compare fertility rates of fresh versus frozen embryo transfer in antagonist IVF cycles. Methods This cohort study was performed on 105 patients referred to the infertility clinic of Besat Hospital in Sanandaj. These patients were admitted to this infertility clinic from March 2014 to March 2020. Inclusion criteria were infertile couples treated with antagonistic IVF cycle. In this study, we compared the fertility rate in antagonist IVF cycles in two patient groups, the group that fresh embryo was transferred, vs the group that received frozen-thawed embryo. Data collected during this study from both groups were analyzed and compared using SPSS statistical software. Results In this study, out of 105 patients included in the project, 48 were in the fresh embryo transfer group, and 57 were in the frozen embryo transfer group. The rate of chemical pregnancy was 12 (25%) in the fresh group and 15 (26.3%) in the frozen group (P: 0.878); The clinical pregnancy rate was 11 (22.9%) in the fresh group and 11 (19.3%) in the frozen group (P: 0.650); The rate of abortion in the fresh group was 3 (6.3%), and in the frozen group was 8 (14%) (P: 0.194); and live birth rate was 9 (18.8%) in fresh group, compared with 7 (12.3%) in the frozen group (P: 0.358). Conclusion The difference in rate of chemical pregnancy, clinical pregnancy, abortion, and live birth in antagonistic IVF cycles in the two groups of fresh embryo transfer versus frozen embryo transfer is not statistically significant. Although not statistically significant, the percentage of chemical pregnancy was higher in the frozen embryo transfer group. The percentage of abortion was also higher in the frozen embryo transfer group, and the percentage of clinical pregnancy and live birth were higher in fresh embryo transfer group.