scholarly journals Reflux Esophagitis and Fatigue: Are They Related?

2021 ◽  
Author(s):  
Sung-Goo Kang ◽  
Hyun jee Hwang ◽  
Youngwoo Kim ◽  
Junseak Lee ◽  
Jung Hwan Oh ◽  
...  
Keyword(s):  
Reflux Esophagitis ◽  
Daytime Sleepiness ◽  
Depression Scale ◽  
Acid Reflux ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Symptomatic Group ◽  
Screening Endoscopy ◽  
Symptomatic Gerd ◽  
Gerd Symptoms

Abstract Background: Gastroesophageal reflux disease (GERD) is a chronic, recurrent disease. Reflux esophagitis can interfere with sleep via acid reflux, which could cause daytime sleepiness or fatigue. However, little is known about the association between reflux esophagitis and fatigueObjectives: We evaluated the association between fatigue and reflux esophagitis in subjects seen at health check-ups.Methods: Consecutive patients who were scheduled for screening endoscopy were enrolled prospectively at the Comprehensive Medical Examination Center of St. Vincent Hospital and Eunpyeong St. Mary's Hospital, Korea. Three validated questionnaires were used to assess fatigue, daytime hypersomnolence, anxiety, and depression: the Multidimensional Fatigue Inventory-Korean version (MFI-K), Epworth Sleepiness Scale (ESS), and Hospital Anxiety and Depression Scale (HADS).Results: We investigated 497 consecutive eligible subjects. The reflux esophagitis and symptomatic GERD groups comprised 103 (20.7%) and 92 (18.5%) subjects, respectively. The MFI-K total, ESS, HADS-anxiety, and HADS-depression scores did not differ between the esophagitis and non-esophagitis groups (50.0±11.5 vs. 49.7±10.9, P=0.661; 6.2±2.8 vs. 6.1±3.1, P=0.987; 5.8±3.1 vs. 5.2±3.2, P=0.060; 6.2±3.6 vs. 6.0±3.3, P=0.561). However, the MFI-K total, ESS, HADS-anxiety, and HADS-depression scores were higher in the symptomatic group than in the non-symptomatic group (54.7±12.7 vs. 48.6±10.3, P<0.001; 7.1±3.5 vs. 5.9±2.9, P=0.002; 6.4±3.3 vs. 5.1±3.1, P<0.001; 7.5±4.0 vs. 5.7±3.1, P<0.001). Multiple regression analysis showed that MFI-K total was correlated with GERD symptoms (P=0.021), women (P=0.001), anxiety (P<0.001) and depression (P<0.001). Conclusion: There was no statistically significant association in which reflux esophagitis could cause daytime sleepiness, fatigue, anxiety, or depression. However, fatigue was associated with GERD symptoms, women, anxiety and depression. Further studies should clarify the association between fatigue and reflux esophagitis.

scholarly journals Reflux Esophagitis and Fatigue: Are They Related?

2020 ◽  
Author(s):  
Sung-Goo Kang ◽  
Hyun jee Hwang ◽  
Youngwoo Kim ◽  
Junseak Lee ◽  
Jung Hwan Oh ◽  
...  
Keyword(s):  
Reflux Esophagitis ◽  
Daytime Sleepiness ◽  
Depression Scale ◽  
Acid Reflux ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Symptomatic Group ◽  
Screening Endoscopy ◽  
Symptomatic Gerd ◽  
Gerd Symptoms

Abstract Background: Gastroesophageal reflux disease (GERD) is a chronic, recurrent disease. Reflux esophagitis can interfere with sleep via acid reflux, which could cause daytime sleepiness or fatigue. However, little is known about the association between reflux esophagitis and fatigueObjectives: We evaluated the association between fatigue and reflux esophagitis in subjects seen at health check-ups.Methods: Consecutive patients who were scheduled for screening endoscopy were enrolled prospectively at the Comprehensive Medical Examination Center of St. Vincent Hospital and Eunpyeong St. Mary's Hospital, Korea. Three validated questionnaires were used to assess fatigue, daytime hypersomnolence, anxiety, and depression: the Multidimensional Fatigue Inventory-Korean version (MFI-K), Epworth Sleepiness Scale (ESS), and Hospital Anxiety and Depression Scale (HADS).Results: We investigated 497 consecutive eligible subjects. The reflux esophagitis and symptomatic GERD groups comprised 103 (20.7%) and 92 (18.5%) subjects, respectively. The MFI-K total, ESS, HADS-anxiety, and HADS-depression scores did not differ between the esophagitis and non-esophagitis groups (50.0±11.5 vs. 49.7±10.9, P=0.769; 6.2±2.8 vs. 6.1±3.1, P=0.819; 5.8±3.1 vs. 5.2±3.2, P=0.069; 6.2±3.6 vs. 6.0±3.3, P=0.527). However, the MFI-K total, ESS, HADS-anxiety, and HADS-depression scores were higher in the symptomatic group than in the non-symptomatic group (54.7±12.7 vs. 48.6±10.3, P<0.001; 7.1±3.5 vs. 5.9±2.9, P=0.002; 6.4±3.3 vs. 5.1±3.1, P<0.001; 7.5±4.0 vs. 5.7±3.1, P<0.001). In addition, HADS-depression was correlated with the MFI-K score (P<0.001).Conclusion: There was no statistically significant association in which reflux esophagitis could cause daytime sleepiness, fatigue, anxiety, or depression, but GERD symptoms were associated with all of these. Depression was also associated with fatigue. Further studies should clarify the association between fatigue and reflux esophagitis.

scholarly journals Reflux Esophagitis and Fatigue: Are They Related?

2020 ◽  
Author(s):  
Sung-Goo Kang ◽  
Hyun jee Hwang ◽  
Youngwoo Kim ◽  
Junseak Lee ◽  
Jung Hwan Oh ◽  
...  
Keyword(s):  
Reflux Esophagitis ◽  
Daytime Sleepiness ◽  
Depression Scale ◽  
Acid Reflux ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Symptomatic Group ◽  
Screening Endoscopy ◽  
Symptomatic Gerd ◽  
Gerd Symptoms

Abstract Background: Gastroesophageal reflux disease (GERD) is a chronic, recurrent disease. Reflux esophagitis can interfere with sleep via acid reflux, which could cause daytime sleepiness or fatigue. However, little is known about the association between reflux esophagitis and fatigueObjectives: We evaluated the association between fatigue and reflux esophagitis in subjects seen at health check-ups.Methods: Consecutive patients who were scheduled for screening endoscopy were enrolled prospectively at the Comprehensive Medical Examination Center of St. Vincent Hospital and Eunpyeong St. Mary's Hospital, Korea. Three validated questionnaires were used to assess fatigue, daytime hypersomnolence, anxiety, and depression: the Multidimensional Fatigue Inventory-Korean version (MFI-K), Epworth Sleepiness Scale (ESS), and Hospital Anxiety and Depression Scale (HADS).Results: We investigated 497 consecutive eligible subjects. The reflux esophagitis and symptomatic GERD groups comprised 103 (20.7%) and 92 (18.5%) subjects, respectively. The MFI-K total, ESS, HADS-anxiety, and HADS-depression scores did not differ between the esophagitis and non-esophagitis groups (50.0±11.5 vs. 49.7±10.9, P=0.769; 6.2±2.8 vs. 6.1±3.1, P=0.819; 5.8±3.1 vs. 5.2±3.2, P=0.069; 6.2±3.6 vs. 6.0±3.3, P=0.527). However, the MFI-K total, ESS, HADS-anxiety, and HADS-depression scores were higher in the symptomatic group than in the non-symptomatic group (54.7±12.7 vs. 48.6±10.3, P<0.001; 7.1±3.5 vs. 5.9±2.9, P=0.002; 6.4±3.3 vs. 5.1±3.1, P<0.001; 7.5±4.0 vs. 5.7±3.1, P<0.001). In addition, HADS-depression was correlated with the MFI-K score (P<0.001).Conclusion: There was no evidence of reflux esophagitis causing daytime sleepiness, fatigue, anxiety, or depression, but GERD symptoms were associated with these. Depression was also associated with fatigue. Further studies should clarify the association between fatigue and reflux esophagitis.

scholarly journals Reflux Esophagitis and Fatigue: Are They Related?

2021 ◽  
Vol 10 (8) ◽  
pp. 1588
Author(s):  
Sung-Goo Kang ◽  
Hyun jee Hwang ◽  
Youngwoo Kim ◽  
Junseak Lee ◽  
Jung Hwan Oh ◽  
...  
Keyword(s):  
Reflux Esophagitis ◽  
Daytime Sleepiness ◽  
Recurrent Disease ◽  
Depression Scale ◽  
Acid Reflux ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Symptomatic Group ◽  
Symptomatic Gerd ◽  
Gerd Symptoms

Gastroesophageal reflux disease (GERD) is a chronic, recurrent disease. Reflux esophagitis can interfere with sleep via acid reflux, which can cause daytime sleepiness or fatigue. However, little is known about the association between reflux esophagitis and fatigue. Objectives: We evaluated the association between fatigue and reflux esophagitis in subjects seen at health check-ups. Methods: Consecutive patients who were scheduled for screening endoscopies were enrolled prospectively at the Comprehensive Medical Examination Center of St. Vincent Hospital and Eunpyeong St. Mary’s Hospital, Korea. Three validated questionnaires were used to assess fatigue, daytime hypersomnolence, anxiety, and depression: the Multidimensional Fatigue Inventory—Korean version (MFI-K), Epworth Sleepiness Scale (ESS), and Hospital Anxiety and Depression Scale (HADS). Results: We investigated 497 consecutive eligible subjects. The reflux esophagitis and symptomatic GERD groups comprised 103 (20.7%) and 92 (18.5%) subjects, respectively. The MFI-K total, ESS, HADS-anxiety, and HADS-depression scores did not differ between the esophagitis and non-esophagitis groups (50.0 ± 11.5 vs. 49.7 ± 10.9, p = 0.661; 6.2 ± 2.8 vs. 6.1 ± 3.1, p = 0.987; 5.8 ± 3.1 vs. 5.2 ± 3.2, p = 0.060; 6.2 ± 3.6 vs. 6.0 ± 3.3, p = 0.561). However, the MFI-K total, ESS, HADS-anxiety, and HADS-depression scores were higher in the symptomatic group than in the non-symptomatic group (54.7 ± 12.7 vs. 48.6 ± 10.3, p < 0.001; 7.1 ± 3.5 vs. 5.9 ± 2.9, p = 0.002; 6.4 ± 3.3 vs. 5.1 ± 3.1, p < 0.001; 7.5 ± 4.0 vs. 5.7 ± 3.1, p < 0.001). Multiple regression analysis showed that the MFI-K total was correlated with GERD symptoms (p = 0.021), women (p = 0.001), anxiety (p < 0.001), and depression (p < 0.001). Conclusion: There was no statistically significant association in which reflux esophagitis could cause daytime sleepiness, fatigue, anxiety, or depression. However, fatigue was associated with GERD symptoms, women, anxiety, and depression. Further studies should clarify the association between fatigue and reflux esophagitis.

Stehen kognitive Funktionen im Zusammenhang mit Angst, Depression und Posttraumatischer Belastungsstörung bei Brustkrebspatientinnen nach onkologischer Behandlung?

2009 ◽  
Vol 57 (1) ◽  
pp. 33-42 ◽  
Author(s):  
Lena Schirmer ◽  
Anja Mehnert ◽  
Angela Scherwath ◽  
Barbara Schleimer ◽  
Frank Schulz-Kindermann ◽  
...  
Keyword(s):  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
Depression Scale ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Kognitive Funktionen

Die in mehreren Studien gefundenen kognitiven Störungen bei Tumorpatienten nach Chemotherapie werden zumeist mit der Zytostatikaneurotoxizität assoziiert. In der vorliegenden Arbeit wird der Zusammenhang von Angst, Depression und Posttraumatischer Belastungsstörung mit der kognitiven Leistungsfähigkeit bei Frauen mit Mammakarzinom untersucht. Insgesamt wurden 76 Brustkrebspatientinnen fünf Jahre nach Abschluss der onkologischen Behandlung mit neuropsychologischen Testverfahren sowie mit der Hospital Anxiety and Depression Scale – Deutsche Version (HADS-D) und der Posttraumatic Stress Disorder Checklist – Civilian Version (PCL-C) untersucht: 23 nach Standard- und 24 nach Hochdosistherapie sowie 29 nach Brustoperation und Strahlentherapie als Vergleichsgruppe. Signifikante Zusammenhänge sind vor allem zwischen kognitiven Funktionen und Intrusionssymptomen einer Posttraumatischen Belastungsstörung (PTBS) festzustellen. Bei Patientinnen nach Standardtherapie weisen Intrusionen der PTBS einen moderaten Zusammenhang mit der globalen kognitiven Beeinträchtigung auf. Die Ergebnisse der Studie deuten auf multidimensionale Einfluss- und moderierende Faktoren bei der Entwicklung kognitiver Defizite bei Brustkrebspatientinnen nach onkologischer Therapie hin.

Hypochondrie in der Allgemeinbevölkerung:

Diagnostica ◽  
2003 ◽  
Vol 49 (1) ◽  
pp. 34-42 ◽  
Author(s):  
Andreas Hinz ◽  
Winfried Rief ◽  
Elmar Brähler
Keyword(s):  
Nottingham Health Profile ◽  
Depression Scale ◽  
Somatoforme Störungen ◽  
Anxiety And Depression ◽  
Multidimensional Fatigue Inventory ◽  
Health Profile ◽  
Hospital Anxiety ◽  
Gießener Beschwerdebogen

Zusammenfassung. Der Whiteley-Index ist ein Instrument zur Erfassung von Hypochondrie. Für diesen Fragebogen wurde eine Normierungs- und Validierungsstudie anhand einer bevölkerungsrepräsentativen Stichprobe (n = 1996) durchgeführt. Hypochondrie zeigt eine etwa lineare Altersabhängigkeit (r = .24). Frauen haben in allen Altersstufen höhere Hypochondrie-Ausprägungen als Männer. Für verschiedene Alters- und Geschlechtsgruppen werden Normwerte bereit gestellt. Die in der Literatur beschriebene dreidimensionale Struktur des Whiteley-Index (Krankheitsängste, somatische Beschwerden und Krankheitsüberzeugung) konnte mit gewissen Einschränkungen bestätigt werden. Validierungsuntersuchungen mit anderen Instrumenten (Hospital Anxiety and Depression Scale, Multidimensional Fatigue Inventory, Gießener Beschwerdebogen, Screening für Somatoforme Störungen und Nottingham Health Profile) zeigten, dass eine auf sieben Items reduzierte Kurzskala der Gesamtskala mit 14 Items ebenbürtig ist. Für differenzierte Analysen wird jedoch die Originalskala empfohlen. Durch die angegebenen Normwerte ist es künftig besser möglich, Patientengruppen verschiedener Alters- und Geschlechtsverteilungen untereinander oder auch mit Stichproben der Normalbevölkerung zu vergleichen.

Hospital Anxiety and Depression Scale--Danish Version

2020 ◽  
Author(s):  
Anne Vinggaard Christensen ◽  
Jane K. Dixon ◽  
Knud Juel ◽  
Ola Ekholm ◽  
Trine Bernholdt Rasmussen ◽  
...  
Keyword(s):  
Depression Scale ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Danish Version

Anxiety Depression and Burden among the Caregivers of Persons with Neurological Illness

2018 ◽  
Vol 9 (2) ◽  
pp. 63
Author(s):  
Anil Kumar Roy ◽  
Nilesh Maruti Gujar ◽  
Arif Ali ◽  
Utpal Borah
Keyword(s):  
Mental Health ◽  
Mental Health Problems ◽  
Depression Scale ◽  
Sampling Technique ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Care Burden ◽  
Neurological Illness ◽  
Rehabilitation Sciences ◽  
Anxiety Depression

Background: Studies have shown that caregivers of the persons with the neurological illness have high levels of psychological distress, depression and caregiver’s burden. The aim of the study was to find out anxiety, depression and caregiver’s burden among the caregivers of persons with neurological illness (PWNI). Method: Thirty caregivers of PWNI attending the Centre of Rehabilitation Sciences, LGB Regional Institute of Mental Health, Tezpur, Assam were selected using purposive sampling technique for the present study. Socio-demographic and clinical data sheet, Zarit Burden Interview Scale and The Hospital Anxiety and Depression Scale were used. Results: The results shown that in Hospital Anxiety and Depression Scale, 26.6% of the caregivers' scores were in the abnormal range in the domain of depression. While in the domain of anxiety, 16.6% scored in the abnormal range. In Zarit Burden of Scale, 13.3% of the caregivers were having little or no burden, 26.6% of the caregivers were having mild to moderate level of burden, 20% were having moderate to severe burden and 30% were having a severe burden of care. Care burden has significant positive correlation with depression (r= .124, p≤ 0.01 and anxiety (r= .124, p≤ 0.05). Conclusion: Caregivers of PWNI have been found to be at higher risk of mental health problems and care burden. The importance of addressing the burden of caregivers involved in the care of PWNI need to be taken into consideration while providing treatment and rehabilitation of PWNI.     Keywords: Anxiety, depression, burden, neurological illness

scholarly journals Changes in insomnia as a risk factor for the incidence and persistence of anxiety and depression: a longitudinal community study

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Magnus Johansson ◽  
Markus Jansson-Fröjmark ◽  
Annika Norell-Clarke ◽  
Steven J. Linton
Keyword(s):  
Risk Factor ◽  
Depression Scale ◽  
Binary Logistic Regression ◽  
Anxiety And Depression ◽  
Hospital Anxiety ◽  
Dynamic Risk ◽  
Increased Risk ◽  
Longitudinal Association ◽  
Development Of Anxiety

Abstract Background The aim of this investigation was to examine the longitudinal association between change in insomnia status and the development of anxiety and depression in the general population. Methods A survey was mailed to 5000 randomly selected individuals (aged 18–70 years) in two Swedish counties. After 6 months, a follow-up survey was sent to those (n = 2333) who answered the first questionnaire. The follow-up survey was completed by 1887 individuals (80.9%). The survey consisted of questions indexing insomnia symptomatology, socio-demographic parameters, and the Hospital Anxiety and Depression Scale. Change in insomnia status was assessed by determining insomnia at the two time-points and then calculating a change index reflecting incidence (from non-insomnia to insomnia), remission (from insomnia to non-insomnia), or status quo (no change). Multivariate binary logistic regression analyses were used to examine the aim. Results Incident insomnia was significantly associated with an increased risk for the development of new cases of both anxiety (OR = 0.32, p < .05) and depression (OR = 0.43, p < .05) 6 months later. Incident insomnia emerged also as significantly associated with an elevated risk for the persistence of depression (OR = 0.30, p < .05), but not for anxiety. Conclusions This study extends previous research in that incidence in insomnia was shown to independently increase the risk for the development of anxiety and depression as well as for the maintenance of depression. The findings imply that insomnia may be viewed as a dynamic risk factor for anxiety and depression, which might have implications for preventative work.

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