scholarly journals Cohort profile: Why do people keep hurting their back?

2020 ◽  
Author(s):  
David Murray Klyne ◽  
Wolbert van den Hoorn ◽  
Mary Frances Barbe ◽  
Jacek Cholewicki ◽  
Leanne Hall ◽  
...  

Abstract Objective: Low back pain (LBP) is one of the most disabling and costly conditions worldwide. It remains unclear why many individuals experience persistent and recurrent symptoms after an acute episode whereas others do not. A longitudinal cohort study was established to address this problem. We aimed to; (1) evaluate whether promising and potentially modifiable biological, psychological, social and behavioural factors, along with their possible interactions, predict LBP outcome after an acute episode; (2) compare these factors between individuals with and without acute LBP; and (3) evaluate the time-course of changes in these factors from LBP onset. This paper outlines the methodology and compares baseline characteristics between acute LBP and control, and LBP participants with and without follow-up. Results: 133 individuals with acute LBP and 74 pain-free individuals participated. Bio-psycho-social and behavioural measures were collected at baseline and 3-monthly for 12 months (LBP) or 3 months (control). Pain and disability were recorded fortnightly. Baseline characteristics were mostly similar between those who did and did not return for follow-up. Initial analyses of this cohort have revealed important insights into the pathways involved in acute-to-chronic LBP. These and future findings will provide new targets for treatment and prevention of persistent and recurrent LBP.

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
David M. Klyne ◽  
Wolbert van den Hoorn ◽  
Mary F. Barbe ◽  
Jacek Cholewicki ◽  
Leanne M. Hall ◽  
...  

Abstract Objective Low back pain (LBP) is one of the most disabling and costly conditions worldwide. It remains unclear why many individuals experience persistent and recurrent symptoms after an acute episode whereas others do not. A longitudinal cohort study was established to address this problem. We aimed to; (1) evaluate whether promising and potentially modifiable biological, psychological, social and behavioural factors, along with their possible interactions, predict LBP outcome after an acute episode; (2) compare these factors between individuals with and without acute LBP; and (3) evaluate the time-course of changes in these factors from LBP onset. This paper outlines the methodology and compares baseline characteristics between acute LBP and control, and LBP participants with and without follow-up. Results 133 individuals with acute LBP and 74 pain-free individuals participated. Bio-psycho-social and behavioural measures were collected at baseline and 3-monthly for 12 months (LBP) or 3 months (control). Pain and disability were recorded fortnightly. Baseline characteristics were mostly similar between those who did and did not return for follow-up. Initial analyses of this cohort have revealed important insights into the pathways involved in acute-to-chronic LBP. These and future findings will provide new targets for treatment and prevention of persistent and recurrent LBP.


2020 ◽  
Author(s):  
David Murray Klyne ◽  
Wolbert van den Hoorn ◽  
Mary Frances Barbe ◽  
Jacek Cholewicki ◽  
Leanne Hall ◽  
...  

Abstract Objective Low back pain (LBP) is one of the most disabling and costly conditions worldwide. It remains unclear why many individuals experience persistent and recurrent symptoms after an acute episode whereas others do not. A longitudinal cohort study was established to address this problem. We aimed to; (1) evaluate whether promising and potentially modifiable biological, psychological, social and behavioural factors, along with their possible interactions, predict LBP outcome after an acute episode; (2) compare these factors between individuals with and without acute LBP; and (3) evaluate the time-course of changes in these factors from LBP onset. This paper outlines the methodology and compares baseline characteristics between acute LBP and control, and LBP participants with and without follow-up.Results 133 individuals with acute LBP and 74 pain-free individuals participated. Bio-psycho-social and behavioural measures were collected at baseline and 3-monthly for 12 months (LBP) or 3 months (control). Pain and disability were recorded fortnightly. Baseline characteristics were mostly similar between those who did and did not return for follow-up. Initial analyses of this cohort have revealed important insights into the pathways involved in acute-to-chronic LBP. These and future findings will provide new targets for treatment and prevention of persistent and recurrent LBP.


2013 ◽  
Vol 93 (12) ◽  
pp. 1603-1614 ◽  
Author(s):  
Karin Verkerk ◽  
Pim A.J. Luijsterburg ◽  
Martijn W. Heymans ◽  
Inge Ronchetti ◽  
Annelies L. Pool-Goudzwaard ◽  
...  

Background Few data are available on the course of and predictors for disability in patients with chronic nonspecific low back pain (CNSLBP). Objective The purpose of this study was to describe the course of disability and identify clinically important prognostic factors of low-back-pain–specific disability in patients with CNSLBP receiving multidisciplinary therapy. Design A prospective cohort study was conducted. Methods A total of 1,760 patients with CNSLBP who received multidisciplinary therapy were evaluated for their course of disability and prognostic factors at baseline and at 2-, 5-, and 12-month follow-ups. Recovery was defined as 30% reduction in low back pain–specific disability at follow-up compared with baseline and as absolute recovery if the score on the Quebec Back Pain Disability Scale (QBPDS) was ≤20 points at follow-up. Potential prognostic factors were identified using multivariable logistic regression analysis. Results Mean patient-reported disability scores on the QBPDS ranged from 51.7 (SD=15.6) at baseline to 31.7 (SD=15.2), 31.1 (SD=18.2), and 29.1 (SD=20.0) at 2, 5, and 12 months, respectively. The prognostic factors identified for recovery at 5 and 12 months were younger age and high scores on disability and on the 36-Item Short-Form Health Survey (SF-36) (Physical and Mental Component Summaries) at baseline. In addition, at 5-month follow-up, a shorter duration of complaints was a positive predictor, and having no comorbidity and less pain at baseline were additional predictors at 12-month follow-up. Limitations Missing values at 5- and 12-month follow-ups were 11.1% and 45.2%, respectively. Conclusion After multidisciplinary treatment, the course of disability in patients with CNSLBP continued to decline over a 12-month period. At 5- and 12-month follow-ups, prognostic factors were identified for a clinically relevant decrease in disability scores on the QBPDS.


2015 ◽  
Vol 47 (9) ◽  
pp. 854-859 ◽  
Author(s):  
K Verkerk ◽  
P Luijsterburg ◽  
A Pool-Goudzwaard ◽  
M Heymans ◽  
I Ronchetti ◽  
...  

2016 ◽  
Vol 25 (4) ◽  
pp. 1234-1241 ◽  
Author(s):  
Evelien I. T. de Schepper ◽  
Bart W. Koes ◽  
Edwin H. G. Oei ◽  
Sita M. A. Bierma-Zeinstra ◽  
Pim A. J. Luijsterburg

2017 ◽  
Vol 21 (6) ◽  
pp. 1131-1138 ◽  
Author(s):  
Gitte Kingo Vesterlund ◽  
Amélie Cléo Keller ◽  
Berit Lilienthal Heitmann

AbstractObjectiveObesity as well as job strain is increasing, and job strain might contribute to weight gain. The objective of the current study was to examine associations between longitudinal alterations in the components of job strain and subsequent weight gain.DesignThe study was designed as a prospective cohort study with three questionnaire surveys enabling measurement of job-strain alterations over 6 years and subsequent measurements of weight gain after further 10 years of follow-up. ANCOVA and trend analyses were conducted. Job demands were measured as job busyness and speed, and control as amount of influence.SettingEmployed nurses in Denmark.SubjectsWe included a sub-sample of 6188 female nurses from the Danish Nurse Cohort, which consisted of the nurses who participated in surveys in 1993, 1999 and 2009.ResultsA linear trend in weight gain was seen in nurses who were often busy in 1999 between those who were rarely v. sometimes v. often busy in 1993 (P=0·03), with the largest weight gain in individuals with sustained high busyness in both years. Loss of influence between 1993 and 1999 was associated with larger subsequent weight gain than sustained high influence (P=0·003) or sustained low influence (P=0·02). For speed, no associations were found.ConclusionsBusyness, speed and influence differed in their relationship to subsequent weight gain. A decrease in job influence and a sustained burden of busyness were most strongly related to subsequent weight gain. Focus on job strain reduction and healthy diet is essential for public health.


2015 ◽  
Vol 19 (8) ◽  
pp. 1101-1110 ◽  
Author(s):  
K. Verkerk ◽  
P.A.J. Luijsterburg ◽  
M.W. Heymans ◽  
I. Ronchetti ◽  
A.L. Pool-Goudzwaard ◽  
...  

2021 ◽  
Author(s):  
Fuming Zheng ◽  
Shufeng Liu ◽  
Shanshan Zhang ◽  
Qiuhua yu ◽  
Wai Leung Ambrose Lo ◽  
...  

Abstract Objectives: The utilization of mobile health (m-health) has rapidly expanded during the COVID-19 pandemic, and there is still a lack of relevant clinical data pertaining to chronic low-back pain(CLBP)management. This study was designed to compare the effectiveness of m-health based exercise (via guidance plus education) versus exercise (via guidance) during CLBP management.Methods: Participants (n = 40) were randomly assigned to intervention and control groups. The intervention group received m-health based exercise (via guidance plus education), whereas the control group received m-health based exercise (via guidance). The exercise prescription video and educational content were sent to participants by the application (app), Ding Talk. Repeated-measures analysis of variance was used to test the baseline’s intervention effects, 6-week follow-up, and 18-week follow-up. We selected function(Roland and Morris Disability Questionnaire)and pain intensity (current, mean, and most severe Numeric Rating Scale in the last 2 weeks)as the primary outcomes, changes of negative emotion (depression, anxious), and quality of life as the secondary outcomes.Results: Time’s significant effect was found in pain, function, and health-related quality of life in both groups, but time did not show significant interaction effects. Participants were able to use m-based education with their anxiety and depression after treatment, but the relief only lasted until Week 6. No differences were found on the aspect of mental health-related quality of life.Conclusion: M-health based exercise (via guidance) is a convenient and effective method to treat CLBP. Additionally, plus education is more helpful in relieving short-term negative emotions and improving treatment adherence than guidance only. However, at the last follow-up(18-week), no significant differences were found between the intervention and control groups.


2021 ◽  
Author(s):  
Ashleigh Cara Stewart ◽  
Reece Cossar ◽  
Shelley Walker ◽  
Anna Lee Wilkinson ◽  
Brendan Quinn ◽  
...  

Abstract Background There are significant challenges associated with studies of people released from custodial settings, including loss to follow-up in the community. Interpretation of findings with consideration of differences between those followed up and those not followed up is critical in the development of evidence-informed policies and practices. We describe attrition bias in the Prison and Transition Health (PATH) prospective cohort study, and strategies employed to minimise attrition.Methods PATH involves 400 men with a history of injecting drug use recruited from three prisons in Victoria, Australia. Four interviews were conducted: one pre-release (‘baseline’) and three interviews at approximately 3, 12, and 24 months post-release (‘follow-up’). We assessed differences in baseline characteristics between those retained and not retained in the study, using two-sample tests of proportions and t-tests.Results Most participants (85%) completed at least one follow-up interview and 162 (42%) completed all three follow-up interviews. Retained participants were younger than those lost to follow-up (mean diff − 3.1 years, 95% CI -5.3, -0.9). There were no other statistically significant differences observed in baseline characteristics.Conclusion The high proportion of participants retained in the PATH cohort study via comprehensive follow-up procedures, coupled with extensive record linkage to a range of administrative datasets, is a considerable strength of the study. Our findings highlight how strategic and comprehensive follow-up procedures, frequent contact with participants and secondary contacts, and established working relationships with the relevant government departments can improve study retention and potentially minimise attrition bias.


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