scholarly journals Network Analysis for Estimating Standardization Trends in Genomics

Author(s):  
Eun Bit Bae ◽  
SeJin Nam ◽  
Sun-Ju Ahn

Abstract With the development of biotechnology in genomics, such as droplet digital PCR, sequencing device, gene analysis software, an increase in the clinical application of those new developed technologies in genomics is observed. However, the lack of established international standards regarding the use of genomics in clinics is of concern. To visualize trend of international standards in clinical genomics and explore high demanded sub-specific field, we performed a social network analysis. We searched 16,538 articles using the search keywords, “genomics and standard” and “clinical genomic sequence and standard”. All terms extracted from full text articles were classified into academic and technical categories and conducted general linear model analysis. Assuming from the results, research in the fields of software, proteomics and genetics terminology categories is likely to increase. From our results, such international critical issue of genomics, human genome project in 2003, primary US-FDA approval of sequencing device in 2013, and pandemic state of COVID-19 in 2020, were affected to research of standard in genomics. In further proposal and standardization of new items, summing critical social issues and research trends, we could suggest and considering promising sub-specific field of genomics.

1999 ◽  
Vol 8 (3) ◽  
pp. 161-168 ◽  
Author(s):  
Glen A. Evans

The Human Genome Project is a massive government and privately funded undertaking to sequence the entire human genome and discover all 80,000 human genes in less than 15 years. As the project nears completion in the first decade of the 21st century, the ramifications of public availability of this vast amount of biological information are likely to pervade society. The legal, ethical and social issues raised by the genome project and associated biological research are expected to have a profound and long lasting impact on daily life. How society deals with the many emerging issues involving genetic privacy, designer babies, and the transformation of medical care among others will be a major focus of public and governmental discussion in the next decade.


Author(s):  
Gregory P. Loos

The World Trade Organization (WTO) was formed in 1994 as the first multilateral trade organization with enforcement authority over national governments. A country's domestic standards cannot be more restrictive than international standards for trade. WTO seeks to “harmonize” individual domestic policies into uniform global standards and encompasses trade-related aspects of health, public safety, and environmental protection. These issues are transnational and pose enormous challenges to traditional governance structures. Most governments are not equipped to manage problems that transcend their borders. Moreover, international governance in social issues—with the possible exception of public health—is still in its infancy. Many groups are concerned that local public interests will be subjugated to global corporate interests. The article looks at the social ramifications of world trade policy and concludes that world trade must be balanced with sustainable environments and human health.


2018 ◽  
Vol 11 (4) ◽  
pp. 433-446 ◽  
Author(s):  
Fallon R. Mitchell ◽  
Sara Santarossa ◽  
Sarah J. Woodruff

The present study aimed to explore the interactions and influences that occurred on Twitter after Joey Julius’s (NCAA athlete, Penn State Football) and Mike Marjama’s (MLB player, Seattle Mariners) eating-disorder (ED) diagnoses were revealed. Corresponding with the publicizing of each athlete’s ED, all publicly tagged Twitter media using @joey_julius, Joey Julius, @MMarjama, and Mike Marjama were collected using Netlytic software and analyzed. Text analysis revealed that the conversation was supportive and focused on feelings and size. Social network analysis, based on 5 network properties, showed that Joey Julius invoked a larger conversation but that both athletes’ conversations were single sided. Athlete advocacy on social media should be further explored, as it may contribute to changing societal opinion regarding social issues such as EDs.


1989 ◽  
Vol 3 (3) ◽  
pp. 279-298 ◽  
Author(s):  
G. Larry Mays ◽  
Michelle Olszta

Prison litigation has been a critical issue for criminal justice and legal scholars, and for correctional practitioners for three decades. It generally is agreed that lawsuits filed by prison inmates and the attention given these suits by the federal courts have served to heighten the debate over the role of prisons in our society. Additionally, from an intergovernmental perspective, much concern has been expressed over the federal courts' role in supervising state prison operations. This article examines a number of legal and social issues that have been raised in prison litigation.


2010 ◽  
Vol 104 (8) ◽  
pp. 1112-1119 ◽  
Author(s):  
Mark Weir ◽  
Karine Morin ◽  
Nola Ries ◽  
David Castle

Nutritional genomics has reached the public through applications of the Human Genome Project offered direct to consumers (DTC). The ability to pursue nutrigenetic testing without the involvement of a health care professional has received considerable attention from academic and policy commentators. To better understand the knowledge and attitudes of Canadian health care professionals regarding nutritional genomics and nutrigenetic testing, qualitative research in the form of focus group discussions was undertaken. Four key themes emerged: (1) concerns over DTC testing; (2) lack of health care professional competency; (3) genetic scepticism and inevitability; (4) expectation of regulation. Together, they indicate that health care professionals have little knowledge about nutritional genomics and hold contradictory attitudes towards genomics in general, and to nutritional genomics in particular. Respondents argue in favour of a delivery model where health care professionals act as intermediaries. They are also aware of their lack of competency to provide such services. To ensure greater public protection, respondents cite the importance of more stringent regulatory oversight of DTC genetic testing. Whether such an approach is necessary to address the various ethical and social issues raised by nutrigenetic testing remains an open debate.


2021 ◽  
Vol 3 (2) ◽  
Author(s):  
Edwin Rommel ◽  
Amin Wibowo ◽  
Nurul Indarti ◽  
Ely Susanto

Introduction/Main Objectives: This study aims to depict the scientific landscape for the innovation policy mix (IPM) from 2012 to 2019 since its re-conceptualization by Flanagan, Uyarra, and Laranja (2011).Background Problems: The seminal work has broadened policy mix thinking with social issues impacting innovation. Since every organization is part of the innovation policy system, this study takes the first step to introduce IPM into management fields by identifying and discussing subsequent works in research trajectories.Novelty: This study shows the remarkable progress toward a mature concept through IPM’s definition, characteristics, and boundaries. As a new string of interdisciplinary social science research, some opportunities and challenges are revealed, allowing future studies to be conducted in more theoretically sounding research traditions.Research Methods: This study applies systematic literature network analysis (SLNA) relying on objective measures from keyword co-occurrences and co-citations networks. It includes 60 articles analyzed using open-source software, i.e., Publish or Perish, Google Scholar database, VOSviewer, and the web-based Local Citation Network.Finding/Results: There are three clusters in the main path of research trajectories, i.e., IPM’s conceptualization, its characteristics for evaluation and measurement, and contextualization. Future research directions are proposed to advance our understanding of the organizational environment and its impact on innovation.Conclusion: IPM studies have opened opportunities to test and extend theories in strategic management and organization studies, especially for leaders who make decisions in the face of dynamic and demanding environments. Moreover, contextualization in developing countries would be a worthwhile exercise by considering the institutional and cultural context.


Author(s):  
Wendong Wu ◽  
Fang He ◽  
Taozhi Zhuang ◽  
Yuan Yi

Currently, many large Chinese cities have entered the postindustrial era, leaving a large amount of vacant, inefficiently utilized industrial land and buildings in the inner cities. Industrial land redevelopment (ILR) can benefit cities in multiple ways, such as by increasing urban public space, improving the quality of life of citizens, and improving the environment, and is considered an effective approach to enhance people’s wellbeing. However, large-scale ILR projects often raise a series of social issues in practice, such as injustice and inequality. To address complex urban issues, ILR requires multifaceted, coordinated, and comprehensive strategies involving multitudinous stakeholders. A profound understanding of diverse stakeholders in the decision-making of ILR is a vital step in enhancing the sustainability of ILR. The aim of this paper is to use Shanghai as a case study to understand the diverse stakeholders and their participation during the decision-making of ILR in China. Interviews and questionnaires were used to collect data. Stakeholder analysis (SA) and social network analysis (SNA) were used as complementary research methodologies in this paper. First, stakeholders who participated in the decision-making of ILR were identified. Then, the characteristics of various stakeholders, including power, interests, and knowledge, were analyzed. Following this, the interactive relationships among stakeholders were explored, and their network structure was examined. Finally, policy recommendations were presented regarding stakeholder participation problems in the decision-making of ILR in China.


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