scholarly journals Prevalence of Post Intensive Care Syndrome Among Japanese Intensive Care Unit Patients: A Prospective, Multicenter, Observational J-PICS Study

2020 ◽  
Author(s):  
Daisuke Kawakami ◽  
Shigeki Fujitani ◽  
Takeshi Morimoto ◽  
Hisashi Dote ◽  
Mumon Takita ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Survey Questionnaire ◽  
Status Change ◽  
Icu Patients ◽  
Sf 36 ◽  
Post Intensive Care Syndrome ◽  
Subjective Significance

Abstract BackgroundMany studies have compared quality of life of post-intensive care syndrome (PICS) patients with age-matched population-based controls, instead of baseline quality of life. Furthermore, many studies on PICS used the 36-item Short Form (SF-36) health survey questionnaire version 2 but lack the data for SF-36 values before and after intensive care unit (ICU) admission. Thus, the clinically important changes in the parameters of SF-36 are unknown. Therefore, we determined the frequency of co-occurrence of PICS impairments at 6 months after ICU admission. We also evaluated the changes in SF-36 health survey questionnaire subscales and interpreted the patients’ subjective significance of impairment.MethodsA prospective, multicenter, observational cohort study was conducted in 16 ICUs across 14 Japanese hospitals. Adult ICU patients expected to receive mechanical ventilation for > 48 hours were enrolled and their 6-month outcome was assessed using the questionnaires. PICS definition was based on the physical status, change in SF-36 physical component score (PCS) ≥ 10 points; mental status, change in SF-36 mental component score ≥ 10 points; cognitive function, Short-Memory Questionnaire (SMQ) score worsened and SMQ score at 6 months < 40. Multivariate logistic regression model was used to identify the factors associated with PICS occurrence. The patients’ subjective significance of physical and mental symptoms was assessed using the 7-scale Global Assessment Rating.ResultsAmong 192 patients, 48 (29.6%) died at 6 months. Among the survivors at 6 months, 96 patients responded to the questionnaire; ≥1 PICS impairment occurred in 61 (63.5%) patients, and ≥ 2 occurred in 19 (19.9%) patients. Physical, mental, and cognitive impairments occurred in 33.3%, 14.6%, and 37.5% patients, respectively. Low education level was associated with PICS occurrence (Odds ratio: 3.8, 95% confidence interval: 1.1–17.9, P=0.036). Based on the patients’ subjective assessment, a 10-point change in PCS indicated moderate negative change.ConclusionsAmong the survivors who received mechanical ventilation, 64% had PICS at 6 months; co-occurrence of PICS impairments occurred in 20%. PICS occurrence was associated with low educational level. Future studies elucidating the minimal clinically important difference of SF-36 scores among the ICU patients and standardizing the PICS definition are required.Trial registrationUMIN000034072

scholarly journals Prevalence of post intensive care syndrome among Japanese intensive care unit patients: A prospective, multicenter, observational J-PICS study

2021 ◽  
Author(s):  
Daisuke Kawakami ◽  
Shigeki Fujitani ◽  
Takeshi Morimoto ◽  
Hisashi Dote ◽  
Mumon Takita ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Icu Patients ◽  
Component Score ◽  
Icu Admission ◽  
Mandatory Education ◽  
Sf 36 ◽  
Post Intensive Care Syndrome ◽  
Subjective Significance

Abstract Background Many studies have compared quality of life of post-intensive care syndrome (PICS) patients with age-matched population-based controls. Many studies on PICS used the 36-item Short Form (SF-36) health survey questionnaire version 2 but lack the data for SF-36 values before and after intensive care unit (ICU) admission. Thus, clinically important changes in the parameters of SF-36 are unknown. Therefore, we determined the frequency of co-occurrence of PICS impairments at 6 months after ICU admission. We also evaluated the changes in SF-36 subscales and interpreted the patients’ subjective significance of impairment.Methods A prospective, multicenter, observational cohort study was conducted in 16 ICUs across 14 hospitals in Japan. Adult ICU patients expected to receive mechanical ventilation for >48 hours were enrolled, and their 6-month outcome was assessed using the questionnaires. PICS definition was based on the physical status, indicated by the change in SF-36 physical component score (PCS) ≥10 points; mental status, indicated by the change in SF-36 mental component score (MCS) ≥10 points; and cognitive function, indicated by the worsening of Short-Memory Questionnaire (SMQ) score and SMQ score at 6 months <40. Multivariate logistic regression model was used to identify the factors associated with PICS occurrence. The patients’ subjective significance of physical and mental symptoms was assessed using the 7-scale Global Assessment Rating to evaluate minimal clinically important difference (MCID).Results Among 192 patients, 48 (25%) died at 6 months. Among the survivors at 6 months, 96 patients responded to the questionnaire; ≥1 PICS impairment occurred in 61 (63.5%) patients, and ≥2 occurred in 17 (17.8%) patients. Physical, mental, and cognitive impairments occurred in 32.3%, 14.6%, and 37.5% patients, respectively. Population with only mandatory education was associated with PICS occurrence (odds ratio: 4.0, 95% confidence interval: 1.1–18.8, P=0.029). The MCID of PCS and MCS scores was 6.5 and 8.0, respectively.Conclusions Among the survivors who received mechanical ventilation, 64% had PICS at 6 months; co-occurrence of PICS impairments occurred in 20%. PICS was associated with population with only mandatory education. Future studies elucidating the MCID of SF-36 scores among ICU patients and standardizing the PICS definition are required. Trial registration UMIN000034072

scholarly journals Prevalence of post-intensive care syndrome among Japanese intensive care unit patients: a prospective, multicenter, observational J-PICS study

Critical Care ◽  
2021 ◽  
Vol 25 (1) ◽  
Author(s):  
Daisuke Kawakami ◽  
Shigeki Fujitani ◽  
Takeshi Morimoto ◽  
Hisashi Dote ◽  
Mumon Takita ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Mechanical Ventilation ◽  
Intensive Care ◽  
Icu Patients ◽  
Component Score ◽  
Icu Admission ◽  
Mandatory Education ◽  
Sf 36 ◽  
Post Intensive Care Syndrome ◽  
Subjective Significance

Abstract Background Many studies have compared quality of life of post-intensive care syndrome (PICS) patients with age-matched population-based controls. Many studies on PICS used the 36-item Short Form (SF-36) health survey questionnaire version 2, but lack the data for SF-36 values before and after intensive care unit (ICU) admission. Thus, clinically important changes in the parameters of SF-36 are unknown. Therefore, we determined the frequency of co-occurrence of PICS impairments at 6 months after ICU admission. We also evaluated the changes in SF-36 subscales and interpreted the patients’ subjective significance of impairment. Methods A prospective, multicenter, observational cohort study was conducted in 16 ICUs across 14 hospitals in Japan. Adult ICU patients expected to receive mechanical ventilation for > 48 h were enrolled, and their 6-month outcome was assessed using the questionnaires. PICS definition was based on the physical status, indicated by the change in SF-36 physical component score (PCS) ≥ 10 points; mental status, indicated by the change in SF-36 mental component score (MCS) ≥ 10 points; and cognitive function, indicated by the worsening of Short-Memory Questionnaire (SMQ) score and SMQ score at 6 months < 40. Multivariate logistic regression model was used to identify the factors associated with PICS occurrence. The patients’ subjective significance of physical and mental symptoms was assessed using the 7-scale Global Assessment Rating to evaluate minimal clinically important difference (MCID). Results Among 192 patients, 48 (25%) died at 6 months. Among the survivors at 6 months, 96 patients responded to the questionnaire; ≥ 1 PICS impairment occurred in 61 (63.5%) patients, and ≥ 2 occurred in 17 (17.8%) patients. Physical, mental, and cognitive impairments occurred in 32.3%, 14.6% and 37.5% patients, respectively. Population with only mandatory education was associated with PICS occurrence (odds ratio: 4.0, 95% CI 1.1–18.8, P = 0.029). The MCID of PCS and MCS scores was 6.5 and 8.0, respectively. Conclusions Among the survivors who received mechanical ventilation, 64% had PICS at 6 months; co-occurrence of PICS impairments occurred in 20%. PICS was associated with population with only mandatory education. Future studies elucidating the MCID of SF-36 scores among ICU patients and standardizing the PICS definition are required. Trial registration UMIN000034072.

scholarly journals Long-term Quality of Life After Intensive Care Unit Admission (a Single-Center Observational Study)

2021 ◽  
Vol 17 (2) ◽  
pp. 72-87
Author(s):  
C. Leggieri ◽  
L. Dezza ◽  
B. Oltolini ◽  
R. Lembo ◽  
B. Noto ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Short Form ◽  
University Hospital ◽  
Synthetic Index ◽  
Sf 36 ◽  
Icu Discharge

Patients may experience long-term physical, psychological and cognitive impairment after intensive care unit (ICU) discharge, a condition commonly described as post-intensive care syndrome. The relative contribution of each of these components to long-term quality of life was never investigated.The aim of this studyis to identify the type and severity of disability and QoL at the discharge from ICU and up to following 6 months.Material and Methods. All patients (n=218) discharged from a university hospital ICU between April 2016 and July 2017 were eligible. Exclusion criteria included: age <18 years, brain or spinal injury, life expectancy <90 days, and ICU stay <12 hours. The Short Form Health Survey (SF-36), and 5-level EuroQoL-5D (EQ-5D-5L) questionnaires were administered at ICU discharge, and at 30-, 90- and 180-days. We compared patients requiring short-term ICU monitoring (IM, Intensive Monitoring,n=109) or patients requiring ICU treatment (IT, Intensive Treatment,n=109).Results. All dimensions of SF-36 and EQ-5D-5L parameters increased from ICU discharge to 180-days, except for the SF-36 Synthetic index linked to mental health (P=0.08). All EQ-5D-5L parameters improved significantly in the IT group, while only Visual Analog Scale Health Perception improved in the IM group.Conclusion. ICU survivors suffer long-term physical and psychological sequelae. The perception of Quality of Life is reduced after ICU discharge. The psychological and cognitive dimensions were more compromised than physical ones. Patients discharged from the ICU may benefit from specific intensive care follow-up clinics addressing their needs in term of psychological and cognitive support.

TRAUMA PATIENTS HAVE MORE SIGNIFICANT IMPAIRMENTS IN HEALTH RELATED QUALITY OF LIFE (HRQOL) COMPARED TO OTHER INTENSIVE CARE UNIT (ICU) PATIENTS

2002 ◽  
Vol 30 (Supplement) ◽  
pp. A140
Author(s):  
Kelsey D Juzwishin ◽  
Gloria Bowen ◽  
Deirdre Hennessy ◽  
Karim Jaber ◽  
Morad Hameed ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Trauma Patients ◽  
Health Related Quality ◽  
Icu Patients ◽  
Related Quality ◽  
Health Related

Post–Intensive Care Syndrome in Family Decision Makers of Long-term Acute Care Hospital Patients

2017 ◽  
Vol 26 (5) ◽  
pp. 416-422 ◽  
Author(s):  
Amy Petrinec
Keyword(s):  
Quality Of Life ◽  
Intensive Care ◽  
Acute Care ◽  
Acute Care Hospitals ◽  
Summary Score ◽  
Decision Makers ◽  
Family Decision ◽  
Post Intensive Care Syndrome

Background Family members of critically ill patients experience indications of post–intensive care syndrome, including anxiety, depression, and posttraumatic stress disorder. Despite increased use of long-term acute care hospitals for critically ill patients, little is known about the impact of long-term hospitalization on patients’ family members. Objectives To examine indications of post–intensive care syndrome, coping strategies, and health-related quality of life among family decision makers during and after patients’ long-term hospitalization. Methods A single-center, prospective, longitudinal descriptive study was undertaken of family decision makers of adult patients admitted to long-term acute care hospitals. Indications of post–intensive care syndrome and coping strategies were measured on the day of hospital admission and 30 and 60 days later. Health-related quality of life was measured by using the Short Form-36, version 2, at admission and 60 days later. Results The sample consisted of 30 family decision makers. On admission, 27% reported moderate to severe anxiety, and 20% reported moderate to severe depression. Among the decision makers, 10% met criteria for a provisional diagnosis of posttraumatic stress disorder. At admission, the mean physical summary score for quality of life was 47.8 (SD, 9.91) and the mean mental summary score was 48.00 (SD, 10.28). No significant changes occurred during the study period. Problem-focused coping was the most frequently used coping strategy at all time points. Conclusion Family decision makers of patients in long-term acute care hospitals have a significant prevalence of indications of post–intensive care syndrome.

Health-related quality-of-life among survivors of acute kidney injury in the intensive care unit: a systematic review

2015 ◽  
Vol 42 (2) ◽  
pp. 137-146 ◽  
Author(s):  
Pierre-Marc Villeneuve ◽  
Edward G. Clark ◽  
Lindsey Sikora ◽  
Manish M. Sood ◽  
Sean M. Bagshaw
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Kidney Injury ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Effects of prolonged intensive care unit stay on quality of life and long-term survival after transthoracic esophageal resection

2006 ◽  
Vol 34 (2) ◽  
pp. 354-362 ◽  
Author(s):  
H A. Cense ◽  
J B. F. Hulscher ◽  
A G. E. M. de Boer ◽  
D A. Dongelmans ◽  
H W. Tilanus ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Intensive Care Unit Stay ◽  
Esophageal Resection ◽  
Term Survival ◽  
Long Term Survival
Sign in / Sign up

Export Citation Format

Share Document