scholarly journals Long-Term Oncologic Safety of Immediate Reconstructive Surgery in Patients with Invasive Breast Cancer: A Retrospective Matched-Cohort Study

2021 ◽  
Author(s):  
Yanni Song ◽  
Shanshan Sun ◽  
Dalin Li ◽  
Jiguang Han ◽  
Ming Niu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Study ◽  
Patient Satisfaction ◽  
Cancer Patients ◽  
Breast Conservation ◽  
Well Being ◽  
Secondary Outcome ◽  
Matched Cohort ◽  
Breast Cancer Patients ◽  
Matched Cohort Study

Abstract Objective Immediate reconstruction (IR) is a safe and effective surgical treatment for patients with breast cancer. We aimed to assess the prognosis, aesthetic outcomes, and patient satisfaction of IR compared with breast conservation surgery (BCS) and total mastectomy (TM).Methods In this retrospective matched-cohort study, we established two cohorts according to the tumor (T) size of breast cancer. In the T≤3cm group, cases (IR) and controls (BCS or TM) were matched for age, pathological tumor size and pathologic nodal status in a 1:1:1 ratio. In the T>3cm group, cases (IR) and controls (TM) were matched with the same factors and ratio. The primary outcome was the 5-year disease-free survival (DFS). The secondary outcome was patient satisfaction and quality of life.Results Between May, 2005 and December, 2014, total 12,678 breast cancer patients were assessed, of which 587 were included (T≤3 cm group: 155 IR vs 155 BCS vs 155 TM; T>3cm group: 61 IR vs 61 TM). In the T≤3 cm cohort, patients underwent IR had no difference compared with those underwent BCS or TM regarding the 5-year DFS (P=0.539); however, an improved aesthetic satisfaction, psychosocial and sexual well-being were achieved in the IR group (P＜0.001). In the T>3 cm cohort, IR group had a worse median 5-year DFS (P=0.044), especially for Her2+ or triple-negative breast carcinoma (TNBC) subtypes compared with TM group. Conclusions IR improves aesthetic satisfaction, psychosocial and sexual well-being for breast cancer patients with T≤3 cm. However, Her2+ or TNBC predict a worse 5-year DFS in the T>3 cm group.

scholarly journals Long-term oncologic safety of immediate reconstructive surgery in patients with invasive breast cancer: a retrospective matched-cohort study

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Yanni Song ◽  
Shanshan Sun ◽  
Dalin Li ◽  
Jiguang Han ◽  
Ming Niu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Study ◽  
Patient Satisfaction ◽  
Cancer Patients ◽  
Invasive Breast Cancer ◽  
Well Being ◽  
Secondary Outcome ◽  
Matched Cohort ◽  
Breast Cancer Patients ◽  
Matched Cohort Study

Abstract Objective Immediate reconstruction (IR) is a safe and effective surgical treatment for patients with breast cancer. We aimed to assess the prognosis, aesthetic outcomes, and patient satisfaction of IR compared with breast conservation surgery (BCS) and total mastectomy (TM). Methods This retrospective matched-cohort study was conducted between May 2005 and December 2014. We established two cohorts according to the tumor (T) size of breast cancer. In the T≤3cm group, cases (IR) and controls (BCS or TM) were matched for age, pathological tumor size, and pathologic nodal status in a 1:1:1 ratio. In the T>3cm group, cases (IR) and controls (TM) were matched with the same factors and ratio. The primary outcome was the 5-year disease-free survival (DFS). The secondary outcome was patient satisfaction and quality of life. Results A total of 12,678 breast cancer patients were assessed for eligibility, of which 587 were included (T≤3 cm group: 155 IR vs 155 BCS vs 155 TM; T>3cm group: 61 IR vs 61 TM). In the T≤3 cm cohort, patients who underwent IR had no difference compared with those who underwent BCS or TM regarding the 5-year DFS (P=0.539); however, an improved aesthetic satisfaction, psychosocial, and sexual well-being were achieved in the IR group (P<0.001). In the T>3 cm cohort, the IR group had a worse median 5-year DFS (P=0.044), especially for Her2+ or triple-negative breast carcinoma (TNBC) subtypes compared with the TM group. Conclusions IR improves aesthetic satisfaction, psychosocial, and sexual well-being for breast cancer patients with T≤3 cm. For patients with T > 3 cm invasive breast cancer, TM is superior to IR as it predicts a better 5-year DFS.

scholarly journals Effect of multidisciplinary team care on the risk of recurrence in breast cancer patients: A national matched cohort study

The Breast ◽  
2020 ◽  
Vol 53 ◽  
pp. 68-76 ◽  
Author(s):  
Chang-Hung Tsai ◽  
Huan-Fa Hsieh ◽  
Ting-Wei Lai ◽  
Pei-Tseng Kung ◽  
Wei-Yin Kuo ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Study ◽  
Cancer Patients ◽  
Multidisciplinary Team ◽  
Matched Cohort ◽  
Breast Cancer Patients ◽  
Risk Of Recurrence ◽  
Matched Cohort Study ◽  
Team Care

scholarly journals Safety of fertility preservation in breast cancer patients in a register-based matched cohort study

2017 ◽  
Vol 167 (3) ◽  
pp. 761-769 ◽  
Author(s):  
Kenny A. Rodriguez-Wallberg ◽  
Sandra Eloranta ◽  
Kamilla Krawiec ◽  
Agneta Lissmats ◽  
Jonas Bergh ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cohort Study ◽  
Cancer Patients ◽  
Fertility Preservation ◽  
Matched Cohort ◽  
Breast Cancer Patients ◽  
Matched Cohort Study

scholarly journals EVA-Scalp: Evaluation of Patient Satisfaction with a Scalp Cooling Device to Prevent Chemotherapy-Induced Alopecia in Breast Cancer Patients

Breast Care ◽  
2019 ◽  
Vol 15 (2) ◽  
pp. 171-177
Author(s):  
Franz-Ferdinand Bitto ◽  
Alexander König ◽  
Thuy  Phan-Brehm ◽  
Thomas Vallbracht ◽  
Julian Gregor Koch ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Patient Satisfaction ◽  
Side Effects ◽  
Cancer Patients ◽  
Well Being ◽  
Scalp Cooling ◽  
Breast Cancer Patients ◽  
Significant Difference ◽  
Patient Selection Criteria

Purpose: Scalp cooling (SC) offers a chance to reduce hair loss (HL), but patient satisfaction, the effect on well-being, as well as patient selection criteria have not been sufficiently assessed yet. Methods: In the EVAScalp trial, SC was offered to 70 breast cancer patients who received chemotherapy between November 2015 and September 2018. For SC, the Paxman-Orbis-II System was used. Satisfaction was measured by a questionnaire evaluating the level of depression with the WHO-5 well-being index (WHO-5) plus questions addressing the patient’s experiences and side effects using the SC device. To evaluate efficacy, documentation by photo, by a physician, and by an HL-diary was conducted. Results: Regarding efficacy, a significant difference between chemotherapy regimens is seen. Anthracycline-based therapies led to a stop of SC in 71% of the patients, whereas taxane-based therapies without anthracyclines were associated with a high acceptance of SC, and 88% of patients with paclitaxel-based therapies continued SC throughout their chemotherapy. Overall, only 7.69% of the patients stopped because of side effects. As an indicator for quality of life, WHO-5 was higher (65.8%) in patients with successful SC compared to in patients who stopped SC because of HL or side effects (only 53.0%). The majority of patients (82.22%) with successful SC would recommend SC to other patients. Conclusions: Patients tolerated SC as long as HL was successfully prevented. The well-being of patients with successful SC was significantly higher than that of patients who stopped SC prematurely. In general, SC is a promising approach and improves patient well-being, but there are still limitations to its utility depending on the chemotherapy regimen used.

scholarly journals Systematic Review on Effectiveness of Patient/Nurse Navigation on Health Outcomes of Breast Cancer Patients

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 81s-81s
Author(s):  
S. Chillakunnel Hussain Rawther ◽  
M. Shivananda Pai ◽  
D. Fernandes ◽  
J. Chakrabarty ◽  
S. Mathew
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Patient Satisfaction ◽  
Psychological Distress ◽  
Health Outcomes ◽  
Cancer Patients ◽  
Well Being ◽  
Breast Cancer Patients ◽  
Navigation Program

Background: Continued advances in technology and cancer treatment have made cancer care more complex. A wide range of healthcare professionals are involved in the care and there is a potential for poor coordination and miscommunication. Hence there is a need to integrate and coordinate care to enhance quality care and improved health outcomes patient navigation approach was introduced by Dr Harold Freeman at Harlem Hospital Centre, the USA in 1990. Some literature identified nurses as a suitable candidate to assume this role. But there is a need to further explore the effectiveness of patient/nurse navigation program for its effectiveness on health outcomes such as anxiety, psychological distress, mood states, quality of life, symptom distress (nausea, vomiting, sleep disturbances) physical well being, psychological well being, coping, support and patient satisfaction. Aim: To synthesize the best available evidence on the effectiveness of patient/nurse navigation program in the care of women with breast cancer. Methods: This review was conducted according to Cochrane guidelines. An extensive literature search was conducted in PubMed, CINAHL, Proquest, Cochrane Library, IndMed (Indian database of studies) and Shodhganga, a reservoir of Indian theses from January 1990-January 2017 for relevant studies published in the English language. The search criteria were limited to randomized controlled trials with patient or nurse navigation interventions compared with routine/usual care interventions without patient/nurse navigator in women with diagnosis of breast cancer aged 18 years and above, at any stage of illness undergoing any treatment in a hospital setting, including inpatient and outpatient/ambulatory care and studies. Results: Out of 238 studies assessed for eligibility only 6 studies were assessed for methodological quality. Quality assessment was done by using Delphi checklist by two independent reviewers. The risks of bias in RCTs were assessed using Cochrane risk of bias tool. Due to the methodological heterogeneity of the studies, a meta-analysis was not performed. The reviewers categorized the main outcomes as quality of life, patient satisfaction with care, anxiety, psychological distress and physical problems and other outcomes (treatment adherence, barriers to care, diagnostic interval, timely access to care, time to completion of treatment, use of health care resources) and presented it in narrative form. Conclusion: This review provides evidence that navigation programs have some benefit on breast cancer patients' health outcomes. The findings from this review show that there are a limited number of studies reporting health outcomes of breast cancer patients from inpatient settings and especially no studies from Asian countries. This warrants the need for developing navigation programs in developing countries especially in Indian setting where no navigation programs are being reported in cancer care.

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