Sensitivity of Pipistrellus Nathusii Kidney Diploid Cell Strain to Viruses of Rhabdoviridae, Reoviridae, Bunyaviridae and Paramixoviridae Families
Abstract The discovery of a significant number of viral pathogens in bat tissue samples and excrement point to a potential prominent role of chiropters in the maintenance and spread of human and animal diseases. It also indicates the potential sensitivity of bat cells to a broad spectrum of viruses. The migratory pipistrelle bat, Pipistrellus nathusii, inhabits northeastern Europe and typically migrates to the southwest. Our study revealed the sensitivity (susceptibility) of a diploid cell line, derived from the kidney of P. nathusii to several transmissible animal disease causative agents such as Epizootic hemorrhagic disease, Akabane disease, Vesicular stomatitis virus and Peste des petit ruminants. High sensitivity of the P. nathusii kidney diploid cell line to viruses from various taxonomic groups allows them to be recommend for extensive use in virological studies.
