A Clinical Trial of Cognitive Behavior Therapy for Psychiatric Comorbidity and Quality of Life with Cancer Patients during Chemotherapy (CPdC)

2021 ◽  
Author(s):  
Qasir Abbas ◽  
Nimra Arooj ◽  
Khawer Bilal Baig ◽  
Muhammad Umer Khan ◽  
Muhammad Khalid ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Psychological Distress ◽  
Cancer Patients ◽  
Death Anxiety ◽  
Satisfaction With Life ◽  
Psychiatric Symptoms ◽  
Self Esteem ◽  
Mean Difference

Abstract BackgroundCancer is a worldwide common illness, it evokes psychological distress at different stages, during chemotherapy patient perceives a variety of psychiatric symptoms due to various medication side-effects and psychological distress. Studies have shown a significant impact of CBT in the management of psychiatric symptoms during chemotherapy. This study aims to investigate the effectiveness of CBT for depression, anxiety, stress, death anxiety, satisfaction with life, and self-esteem among cancer patients during chemotherapy (CPdC).MethodsPlace and duration of the study: Department of Applied Psychology, Government College University Faisalabad in collaboration with Department of Oncology, Allied Hospital Faisalabad from November 20, 2020 and July 31, 2021. A total of 90 cancer patients were enrolled. 70 out of 90 met the eligibility criteria and 60 participants fulfilled all requirements. Participants were randomly allocated to four different groups. The pre-assessment screening was started along with the first trial of chemotherapy. The CBT-based treatment plan was formulated and one session per week was given to each patient for 3 to 4months. Participants’ age range was 18–65 years (M ± SD = 47.51 ± 12.36. Demographic form, DASS, DAS, SWLS, and RSES measures were used. Descriptive, t-test, and repeated measure ANOVA statistics were used to investigate the findings.ResultsResults indicated significant mean difference on the variable of depression, anxiety and stress across four conditions (i.e. F (2, 56) = 39.55, p < .000, η2 = .679; F(2,56) = 73.32, p < .000, η2 = .797; F(2,56) = 119.77, p < .000, η2 = .865 respectively). On death anxiety significant difference across four conditions was found (F (2,56) = 22.71, p < .000, η2 = .549) with large effect size. Furthermore, findings indicated significant mean difference on the variable of satisfaction with life and self-esteem across four conditions was found (F(2,56) = 22.05, p < .000, η2 = .542; F(2,56) = 36.19, p < .000, η2 = .660) with large effect size.ConclusionIt is concluded that CBT played a very effective role to reduce depression, anxiety, and stress-related psychiatric symptoms. CBT reduces the level of death anxiety and improving the quality of life and level of self-esteem among CPdC.Trial Registration: The study trial was registered in the Thai Clinical Trial Registry-TCTR (TCTR20201113002).

PSYCHOLOGICAL REHABILITATION AND SCREENING OF EMOTIONAL STRESS IN CANCER PATIENTS

2017 ◽  
Vol 63 (2) ◽  
pp. 316-319 ◽  
Author(s):  
Valentina Chulkova ◽  
Tatyana Semiglazova ◽  
Margarita Vagaytseva ◽  
Andrey Karitskiy ◽  
Yevgeniy Demin ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Cancer Patient ◽  
Cancer Patients ◽  
Emotional Stress ◽  
Self Esteem ◽  
Breast Cancer Patients ◽  
Psychological Study ◽  
Psychological Assistance

Psychological rehabilitation is an integral part of rehabilitation of a cancer patient. Psychological rehabilitation is aimed at a patient adaptation in the situation of the disease and improvement his quality of life. Understanding of an oncological disease is extreme and (or) crisis situation and monitoring dynamics of the psychological statement of a patient allows using differentiated approach in the provision of professional psychological assistance. The modified scale of self-esteem level of distress (IPOS) was used for screening of mental and emotional stress of cancer patients. There were selected groups of cancer patients who were most in need of professional psychological assistance. Results of a psychological study of one of these groups - breast cancer patients - are presented.

‘Teaching Me to Parent Myself’: The Feasibility of an In-Patient Group Schema Therapy Programme for Complex Trauma

2017 ◽  
Vol 46 (4) ◽  
pp. 463-478
Author(s):  
Rita Younan ◽  
Joan Farrell ◽  
Tamara May
Keyword(s):  
Quality Of Life ◽  
Complex Trauma ◽  
Psychiatric Symptoms ◽  
Self Esteem ◽  
Post Treatment ◽  
Drop Out ◽  
Schema Therapy ◽  
Schema Modes ◽  
Therapy Programme

Background: Group schema therapy is an emerging treatment for personality and other psychiatric disorders. It may be particularly suited to individuals with complex trauma given that early abuse is likely to create maladaptive schemas. Aims: This pilot study explored the feasibility and effectiveness of a 4-week in-patient group schema therapy programme for adults with complex trauma in a psychiatric hospital setting. Method: Thirty-six participants with complex trauma syndrome participated in this open trial. Treatment consisted of 60 hours of group schema therapy and 4 hours of individual schema therapy administered over 4 weeks. Feasibility measures included drop-out rates, qualitative interviews with participants to determine programme acceptability and measures of psychiatric symptoms, self-esteem, quality of life and schema modes pre-, post- and 3 months following the intervention. Results: Drop-out rate for the 4-week program was 11%. Thematic analysis of interview transcripts revealed four major themes: connection, mode language explained emotional states, identifying the origin of the problem and the emotional activation of the programme. Measures of psychiatric symptoms, self-esteem and quality of life showed improvement post-treatment and at 3 months post-treatment. There was a reduction in most maladaptive schema modes pre-/post-treatment. Conclusions: A group schema therapy approach for complex trauma is feasible and demonstrates positive effects on psychiatric symptoms and maladaptive schemas.

Psychological Distress and Health-Related Quality of Life among Head and Neck Cancer Patients during the First Year after Treatment

2016 ◽  
Vol 102 (1) ◽  
pp. 96-102 ◽  
Author(s):  
Maria Benedetta Ninu ◽  
Guido Miccinesi ◽  
Francesco Bulli ◽  
Alessio De Massimi ◽  
Maria Grazia Muraca ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Psychological Distress ◽  
Head And Neck ◽  
Cancer Patients ◽  
First Year ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

scholarly journals M236. AN ASSESSMENT OF THE DIMENSIONALITY OF A ROMANIAN TRANSLATION OF THE SCHIZOTYPAL PERSONALITY QUESTIONNAIRE AND ASSOCIATIONS WITH QUALITY OF LIFE, SELF-ESTEEM, AND LIFE SATISFACTION

2020 ◽  
Vol 46 (Supplement_1) ◽  
pp. S226-S226
Author(s):  
David Barron ◽  
Mona Vintila ◽  
Viren Swami
Keyword(s):  
Quality Of Life ◽  
Life Satisfaction ◽  
Satisfaction With Life ◽  
Factor Model ◽  
Self Esteem ◽  
Order Structure ◽  
Personality Questionnaire ◽  
Schizotypal Personality ◽  
Schizotypal Personality Questionnaire

Abstract Background While the Schizotypal Personality Questionnaire (SPQ; Raine, 1991) is an established measure of self-reported schizotypy, the higher-order structure of its ratings has continued to be debated in numerous translations. Here, we examined the psychometric properties of a Romanian translation of the SPQ and assessed associations with quality of life, self-esteem, and satisfaction with life. Methods In total, 711 university students (488 women, 223 men) from Romania completed a novel translation of the SPQ online alongside measures of quality of life, self-esteem, and life satisfaction. All participants indicated no immediate family history relating to psychosis. Results Using confirmatory factor analysis, we suggest that a 4-dimensional model of SPQ scores had better fit to these data than alternative 3- and 4-factor models. The 4-factor model also demonstrated partial measurement invariance across sex, although sex differences on domain scores were negligible (ηp2 = .01-.02). The 4 SPQ domains were significantly and negatively correlated with all additional measures of quality of life, self-esteem, and satisfaction with life. Further, in predicting scores on these additional measures, the Negative SPQ domain emerged as the strongest predictor, with Paranoid and Disorganised scores also significant predictors. Discussion Romanian SPQ scores demonstrated adequate construct and predictive validity vis-à-vis quality of life, satisfaction with life, and self-esteem. Importantly, our findings highlighted the benefit of a Paranoid factor within the SPQ dimensionality, which provides support for a 4-factor conceptualisation of SPQ scores in a hitherto neglected linguistic group.

scholarly journals Perceived Needs, Psychological Distress and Quality of Life of Elderly Cancer Patients

2012 ◽  
Vol 42 (8) ◽  
pp. 704-710 ◽  
Author(s):  
T. Akechi ◽  
T. Okuyama ◽  
M. Uchida ◽  
T. Nakaguchi ◽  
Y. Ito ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Distress ◽  
Cancer Patients ◽  
Elderly Cancer Patients ◽  
Perceived Needs

Celiac plexus radiosurgery for pain management in advanced cancer patients: An international phase II trial.

2019 ◽  
Vol 37 (4_suppl) ◽  
pp. TPS466-TPS466
Author(s):  
Yaacov Richard Lawrence ◽  
Tikva Meron ◽  
Adam P. Dicker ◽  
Camilla Zimmermann ◽  
Maoz Ben-Ayun ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Pancreatic Cancer ◽  
Clinical Trial ◽  
Cancer Patients ◽  
Short Form ◽  
Pilot Trial ◽  
Celiac Plexus ◽  
High Dose ◽  
Analgesic Use

TPS466 Background: Many cancer patients, especially those with pancreatic cancer, suffer from severe back/epigastric pain. Contemporary approaches (opioids, celiac blocks, systemic chemotherapy) are often inadequate. This clinical trial investigates a new approach in which high-dose radiation (radiosurgery) is focused on the retroperitoneal celiac plexus nerve bundle. Preliminary results from a single institution pilot trial NCT02356406 are promising: pain relief is substantial and side effects minimal. The main aim of the trial is to establish safety/efficacy in the setting of an international multicenter study. Exploratory analyses will examine the relationship between pain reduction and subjects’ quality-of-life, functionality, and caregiver burden. Methods: Eligibility criteria include a diagnosis of metastatic/unresectable malignancy, uncontrolled pain defined as ≥ 5 on 11-point BPI-SF scale despite analgesic use, typical retroperitoneal pain syndrome, prognosis > 8 weeks, ECOG 0-2, anatomical involvement of the celiac plexus (e.g. any pancreatic cancer, or any other cancer involving the celiac trunk). Exclusion criteria include previous upper abdo. radiation. The intervention consists of a single 25 Gy radiation fraction delivered to the celiac plexus, using anterolateral aspect of the aorta from the 12th thoracic to 2nd lumbar vertebral body as a surrogate structure. The primary tumour may be irradiated at physicians’ discretion. Dose-painting technique limits dose to organs at risk. Pain intensity will be measured using Brief Pain Inventory Short Form (BPI-SF), and quality of life with FACT-Hep. The primary endpoint is complete or partial pain response, defined as a decrease between the score immediately before treatment and 3 weeks’ post-treatment. A change of two or more on the BPI 11-point pain scale is defined as clinically significant. Secondary endpoints include other BPI pain endpoints, pain at 6 weeks, analgesic use, toxicity (CTCAE v4.03), quality of life and functional measures. Analgesia is not restricted. Expected accrual is 100 subjects over three years. Supported by Gateway for Cancer Research, additional support from Israel Cancer Association. Clinical trial information: NCT03323489.

Prospective, Longitudinal Quality-of-Life Study of Patients With Head and Neck Cancer: A Feasibility Study Including the EORTC QLQ-C30

1997 ◽  
Vol 116 (6) ◽  
pp. 666-673 ◽  
Author(s):  
Eva Hammerlid ◽  
Kristin Bjordal ◽  
Marianne Ahlner-ELMQVIST ◽  
Magnus Jannert ◽  
Stein Kaasa ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Head And Neck Cancer ◽  
Psychological Distress ◽  
Pilot Study ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Eortc Qlq C30 ◽  
Eortc Qlq

Despite modern advances in the treatment of head and neck cancer, the survival rate fails to improve. Considering the different treatment modalities involved, quality of life has been thought of as an additional end point criterion for use in clinical trials. A Nordic protocol to measure the quality of life of head and neck cancer patients before, during, and after treatment was established. Before the study, a pilot study was done with this protocol. The main purpose of this pilot study was to find out whether this cancer population would answer quality-pf-life questionnaires repeatedly (six times) over a 1-year period and whether the chosen questionnaires—a core questionnaire (European Organisation for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30)), a tumor-specific questionnaire, and a psychological distress measure (Hospital Anxiety and Depression scale (HAD))—were sensitive for changes to functions and symptoms during the study year. The results presented in this article all refer to the pilot study. Forty-eight consecutive patients agreed to participate in the study. The most common tumor locations were the oral cavity (17) and the larynx (12). Almost all patients received combined treatment: 45 of 48 radiation therapy, 18 of 48 chemotherapy, and 17 of 48 surgery. After the primary treatment, 40 patients had complete tumor remission. Four of the 48 patients did not answer any questionnaires and were therefore excluded from the study. Of the remaining 44 patients, 3 died during the study year, and another 6 withdrew for various reasons. Thirty-five (85%) of the 41 patients alive at the 1-year follow-up answered all six questionnaires and thus completed the study. Mailed questionnaires were used throughout the study. All questionnaires were well accepted and found to be sensitive to changes during the study year. The greatest variability was found for symptoms and functions related specifically to head and neck cancer. The symptoms were swallowing difficulties, hoarse voice, sore mouth, dry mouth, and problems with taste. They all showed the same pattern, with an increase of symptoms during and just after finishing the treatment. The HAD scale revealed a high level of psychological distress, with 21% probable cases of psychiatric morbidity at diagnosis. In conclusion, it was shown that the study design and questionnaires were feasible for the forthcoming prospective quality-of-life assessment of Swedish and Norwegian head and neck cancer patients.

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