Adult Extrarenal Teratoid Wilms’ Tumor: A Case Report
Abstract Background: A teratoid Wilms’ tumor (TWT) is a very rare histologic variant of the classical Wilms’ tumor. This tumor development outside kidneys is rare. Extrarenal TWT mainly occurs in children, and reports of adult-related cases are rare. Till now, only seven cases of extrarenal TWT have been reported, among which five cases occurred in children and another two cases was reported in adult. Methods: A retrospective analysis of the clinicopathological characteristics of a case of extrarenal teratoid Wilms’ tumors (TWT) admitted to our hospital and analysis and summary with literature. Results: The case was a 19-year-old woman that presenting with lower, painless abdominal discomfort, and an imaging of an ultrasound and MRI both showed a cystic-solid mass on the right ovary. The patient subsequently underwent a laparoscopic right ovarian cystectomy, The specimen is sent for pathological examination, microscopic examination showed typical morphological features of Wilms’ tumor and predominance of teratoid elements which comprising more than 50% of the tumor. The diagnosis was made as extrarenal TWT in right ovary. After 3 courses of chemotherapy, the patient remains without evidence of disease after twenty-six months of follow-up. Conclusion: Our case is the third reported case of adult extrarenal TWT occurring in ovarian. Careful histomorphological examination and extensive immunohistochemical studies will allow for accurate diagnosis, We reported this case in order to improve the clinicians and pathologist’s understanding of tumors.