scholarly journals Rotating shift workers with vitamin D deficiency have a higher risk of obstructive sleep apnea

Author(s):  
Luiz Antonio Alves Menezes Júnior ◽  
Virgínia Capistrano Fajardo ◽  
Sílvia Nascimento de Freitas ◽  
Fausto Aloisio Pedrosa Pimenta ◽  
George Luiz Lins Machado-Coelho ◽  
...  

Abstract Objectives The aim of the study is evaluate the association of obstructive sleep apnea syndrome (OSA) and vitamin D deficiency (VDD) in shift workers. Methods This cross-sectional study included rotating shift workers in an iron ore extraction company. Participants were classified as VDD when 25(OH)D < 20 ng/mL for a healthy population and 25(OH)D < 30 ng/mL for groups at risk for VDD. Risk of developing OSA classified by Berlin Questionnaire (BQ) and NoSAS score. Data were compared using chi-square analysis with Cramer's V as effect size, and Bonferroni correction. Multivariate logistic regression analysis was performed to investigate whether VDD was associated with OSA risk assessment. Results Among 1461 workers, mostly male (97.4%), younger, aged 30 to 39 years (53.9%), worked shifts for more than 5 years (75.8%). A prevalence of high risk of OSA by BQ was 15.9%, and 32.5% by NoSAS score. Besides, 28.9% had VDD. In multivariate analysis, controlled for confounding factors, workers with VDD had a 79% increased chance of OSA by BQ (OR: 1.79; CI95%: 1.27-2.51) and an 85% increased chance of OSA by NoSAS score (OR: 1.85; CI95% 1.35-2.53). After subgroup analyses, similar results were not observed in workers aged 20-29 years. Conclusion Rotating shift workers with vitamin D deficiency are more likely to have obstructive sleep apnea, assesed by Berlin questionnaire and NoSAS score.

Author(s):  
Banu Musaffa Salepçi ◽  
Benan Caglayan ◽  
Elif Torun Parmaksiz ◽  
Nesrin Kiral ◽  
Ali Fidan ◽  
...  

Medicine ◽  
2016 ◽  
Vol 95 (39) ◽  
pp. e4632 ◽  
Author(s):  
Gamze Ozgurhan ◽  
Aysel Vehapoglu ◽  
Oznur Vermezoglu ◽  
Rabia Nur Temiz ◽  
Asuman Guney ◽  
...  

Author(s):  
Luiz Antônio Alves de Menezes Júnior ◽  
Virgínia Capistrano Fajardo ◽  
Raimundo Marques do Nascimento Neto ◽  
Sílvia Nascimento de Freitas ◽  
Fernando Luiz Pereira de Oliveira ◽  
...  

2015 ◽  
Vol 53 (1) ◽  
pp. 91-96
Author(s):  
Agripina Rascu ◽  
Laura Moise ◽  
Eugenia Naghi ◽  
Alexandra Rascu ◽  
Lavinia Lacatusu

Abstract Sleep Apnea Syndrome (SAS) constitutes a healthcare issue of major importance at international level with a prevalence of 5% in the active population. Consequentially to the induced co-morbidities, the mortality reaches as high as 39% at eight years time lapse from the initial diagnostic. Seldom undiagnosed, the severity spectrum of SAS, in the absence of therapy, only continues to amplify. Here below, we are presenting the case of a 49 years old patient, railroad controller worker, non-smoker and occasionally alcohol user, who was hospitalized in our Clinic for Occupational Medicine. During last year, the patient was accusing excessive daytime somnolence, breath arrests during sleep, intense snoring, morning headaches, morning oral dryness, pin point chest pain, nocturia (4-5 nocturnal urination), concentration difficulties and an overall reduced work capacity. The presumptive diagnostic of Obstructive Sleep Apnea is being considered based on the correlation between the clinical presentation and the Epworth, Stanford and Berlin questionnaire results. The key diagnostic element was the polygraph recording over an 8 hours sleep period. Positive Diagnosis: Obstructive Sleep Apnea severe form. Management and recommendations: (1) Behavioral therapy (weight loss) and (2) CPAP (Continuous Positive Airway Pressure) therapy which was instituted immediately after the positive diagnosis was made. As a consequence, the respiratory symptoms, the frequent episodes of daytime snoozing and the concentration difficulties at work place diminished considerably.


2017 ◽  
Vol 15 (2) ◽  
pp. 136-140
Author(s):  
Carolina Vicaria Rodrigues D’Aurea ◽  
Bruno Gion de Andrade Cerazi ◽  
Antonio Gabriele Laurinavicius ◽  
Carolina Castro Porto Silva Janovsky ◽  
Raquel Dilguerian de Oliveira Conceição ◽  
...  

ABSTRACT Objective To investigate the inter-relation between high sensitivity C-reactive protein and glycated hemoglobin in prediction of risk of obstructive sleep apnea. Methods We included all individuals participating in a check-up program at the Preventive Medicine Center of Hospital Israelita Albert Einstein in 2014. The Berlin questionnaire for risk of obstructive sleep apnea was used, and the high sensitivity C-reactive protein and glycated hemoglobin levels were evaluated. Results The sample included 7,115 participants (age 43.4±9.6 years, 24.4% women). The Berlin questionnaire showed changes in 434 (6.1%) individuals. This finding was associated with high sensitivity C-reactive protein and glycated hemoglobin levels (p<0.001). However, only the association between the Berlin questionnaire result and glycated hemoglobin remained significant in the adjusted multivariate analysis, for the traditional risk factors and for an additional model, including high-density lipoprotein cholesterol and triglycerides. Conclusion The glycated hemoglobin, even below the threshold for diagnosis of diabetes, is independently associated with obstructive sleep apnea syndrome, even after adjustment for obesity and C-reactive protein. These findings suggest a possible pathophysiological link between changes in insulin resistance and obstructive sleep apnea syndrome, independently from obesity or low-grade inflammation.


Author(s):  
Hakan Celikhisar ◽  
Gulay Dasdemir Ilkhan

Abstract Objective: To determine the relationship between frequency of traffic accidents and presence and severity of the disease in bus drivers who are at risk of having obstructive sleep apnea syndrome (OSAS). Method: In the present study, polysomnography (PSG) was applied on 162 city bus drivers directed to the sleep laboratory from a total of 1450 drivers after being determined as risky with regard to OSAS symptoms according to the questionnaire results. Their demographic characteristics, health status and accidents were compiled. Statistical analyses were made for those diagnosed with OSAS according to the PSG result and those with a traffic accident after which comparisons were made. Results: Obstructive sleep apnea syndrome was detected in 127 out of the 162 drivers determined to be risky with regard to OSAS based on the Berlin questionnaire result. While 35% of the drivers were normal according to the polysomnography (PSG) results in the study, 39 (24.1%) were determined as light OSAS, 35 (21.6%) as moderate OSAS and 53 (32.7%) as severe OSAS. While 105 (64.8%) of the cases had no accident, 37 (22.8%) were almost involved in an accident due to sleepiness and 20 (12.3%) were actually involved in an accident. A statistically significant relationship was determined between accident rates and OSAS severity (p:0.009; p<0.05). Conclusion: It was concluded that presence and increased severity of OSAS is an important risk factor for being almost or directly involved in an accident among city bus drivers, even though they were not driving for long distances. 


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