scholarly journals Sonographic Evaluation of Acute Appendicitis -A Study at a Tertiary Care Hospital of Tribal, Hilly, Wayanad in Kerala

Author(s):  
Krishna Kumar ◽  
Kevin Araujo ◽  
Lakshmeesha Lakshmeesha ◽  
Vijayendra Vijayendra

Author(s):  
Vinod Kumar ◽  
Bhupen Songra ◽  
Richa Jain ◽  
Deeksha Mehta

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.



2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Nadia Gulnaz ◽  
Sadia Tasleem ◽  
Farooq Abdullah

Abstract Traditionally acute appendicitis has been a clinical diagnosis based on patients' history and physical examination, but the accuracy of clinical diagnosis ranges from 70-95%. Pre-operative diagnosis of acute appendicitis still remains an enigmatic challenge, because no single test alone can reduce the rate of negative appendectomy. Hence some authors have recommended a combination of two or more investigations to increase accuracy and therefore the use of imaging is gaining support. The objective of the study was to determine the clinical accuracy of ultrasound, combined with inflammatory markers such as CRP, WBC, and neutrophilia keeping histopathology as the gold standard. Methods The study was conducted in a Tertiary care hospital in Peshawar from September 2014 to March 2015 on 250 patients who were clinically diagnosed with acute appendicitis. All these patients underwent u/sound scanning in addition to blood tests. Findings In this study, WBC had the highest sensitivity (77.68%) followed by neutrophil% (69.96%), CRP(67.10%), and U/Sound (62.96%) respectively. While U/Sound had the highest specificity (70.59%) followed by CRP and TLC (64.71% each) and neutrophil% (58.82%) respectively. When all the four tests were combined the sensitivity, specificity, (99.17% and 98.45%) increased significantly. When all four tests were negative, appendicitis could be safely ruled out. Conclusion Acute appendicitis is very unlikely and surgery can be safely deferred in these patients when all tests are negative thereby reducing the negative appendicectomy rates. 



2019 ◽  
Vol 11 (1) ◽  
pp. 72-74
Author(s):  
Sanjay Anarase ◽  
◽  
Yogita Sanjay Anarase ◽  


Author(s):  
Anil Kumar Dadhich ◽  
Atul Kumar Sharma

Background: Acute abdominal pain is a common complaint among emergency department patients. Methods:  A 100 consecutive patients suspected of acute appendicitis who were admitted in department of surgery. They were prospectively evaluated using the modified Alvarado scoring (MAS) to determine whether or not they had acute appendicitis. Result: In present study, out of total 100 patients 78(78%) were have MAS score 7-9, 20% were have 5-6 and 2% have MAS score 1-4. Conclusion: The study shows that use of MASS in patients suspected to have acute appendicitis provides a high degree of diagnostic accuracy. Keywords: Modified Alvarado Score (MAS), acute appendicitis, Patients.



2020 ◽  
Vol 13 (2) ◽  
pp. 65-67
Author(s):  
Ajay Kumar ◽  
◽  
Rajendra , Singh ◽  
Mohammad Eqwal Ahmad ◽  
◽  
...  


2017 ◽  
Vol 4 (3) ◽  
pp. 929 ◽  
Author(s):  
K. Suresh Babu ◽  
S. Savitha

Background: Acute appendicitis is a common problem in children and early adult life. Appendicectomy is immediate or emergency procedure to reduce morbidity and mortality. The present study was conducted to find out clinical profile of acute appendicitis and complications of appendicectomy.Methods: This observational study was conducted among 100 patients diagnosed as acute appendicitis in tertiary care hospital during the year from 2001 to 2002. The clinical profile like age, sex, symptoms of the patients and post-operative complications were recorded. All patients underwent appendicectomy and followed post operatively.Results: Out of hundred patients, 55% were male and 45% were female. Nearly 71% of the patients belonged to the age group of 15-30 years.100% had pain abdomen, 81% had fever and 75% had vomiting. The post-operative complication was 3%.Conclusions: Acute appendicitis is very common in younger age groups shows that whenever young patients present with acute abdominal pain may be considered acute appendicitis. The complication of appendicectomy is very minimum and gives good prognosis.



2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Siripong Sirikurnpiboon ◽  
Suparat Amornpornchareon

Background. The incidence of perforated appendicitis in elderly patients is high and carries increased morbidity and mortality rates. The aim of this study was to identify risk factors of perforation in elderly patients who presented with clinical of acute appendicitis.Methods. This was a retrospective study, reviewing medical records of patients over the age of 60 years who had a confirmed diagnosis of acute appendicitis. Patients were classified into two groups: those with perforated appendicitis and those with nonperforated appendicitis. Demographic data, clinical presentations, and laboratory analysis were compared.Results. Of the 206 acute appendicitis patients over the age of 60 years, perforated appendicitis was found in 106 (50%) patients. The four factors which predicted appendiceal rupture were as follows: male; duration of pain in preadmission period; fever (>38°C); and anorexia. The overall complication rate was 34% in the perforation group and 12.6% in the nonperforation group.Conclusions. The incidence of perforated appendicitis in elderly patients was higher in males and those who had certain clinical features such as fever and anorexia. Duration of pain in the preadmission period was also an important factor in appendiceal rupture. Early diagnosis may decrease the incidence of perforated appendicitis in elderly patients.



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