scholarly journals Measures to Provide Settlements with Quality Drinking Water: Assessment of the Potential by the Example of the Odessa Agglomeration

2021 ◽  
Vol 17 (2) ◽  
pp. 31-45
Author(s):  
Oksana Georhiyivna Tserkovna ◽  

The rapid urbanisation of the settlements of the Odessa agglomeration has negatively affected the quality of the drinking water that is transported to consumers. The purpose of this study was to determine the most effective measures to provide settlements with quality drinking water. In order to achieve this goal, possible options for measures were considered, and an assessment and comparative analysis of the potential of the proposed options were executed. The most effective measures were evaluated on two criteria: compliance with the principles of sustainable development and whether the measures were effective, reliable and comfortable for consumers when implemented. The factors that influenced the decision-making were the situation and conditions of the implementation of the measures, laboratory tests of the source water and laboratory tests of the water after the treatment process and consumer awareness of participation. The findings demonstrated that a measure was effective if it met the stated criteria. The results of the study are planned to be used as reference material in the elaboration of an integrated plan for the development of settlements, for decision-making in the organisation of recreation and health-related areas and for other resource planning activities.

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Lourdes Carhuapoma ◽  
Radhika Avadhani ◽  
Noeleen Ostapkovich ◽  
Karen Lane ◽  
Nichol McBee ◽  
...  

Introduction: Recovery in intracerebral hemorrhage (ICH) is prolonged and unpredictable, resulting in challenges in estimating health-related quality of life (HRQoL). We describe HRQoL and patient disposition for ICH survivors with similar clinical characteristics to ICH patients who had withdrawal of life-sustaining treatment (WoLST). Methods: Using MISTIE III trial data (N = 499), we performed a matched cohort analysis using a published modified severity index (mSI) to compare ICH survivors (N = 379) with WoLST patients (N = 61). We used multivariable logistic regression adjusting for age, Glasgow Coma Score, deep ICH location, stability ICH and intraventricular hemorrhage volume and ≥ 3 comorbidities to create the mSI. After matching survivors with equal mSI to WoLST patients, we compared EuroQoL (EQ) visual analog scale (VAS) scores (US norm 69-76; range 0-100) by mSI quartile and patient disposition. Results: We matched 224 survivors to WoLST patients by mSI (range 0-6.5), with data at all timepoints. Given the large mSI range, EQ VAS scores and patient disposition were evaluated by mSI quartile groups. The median (interquartile range [IQR]) EQ VAS score increase for all mSI groups from day 30 (D30) to 180 (D180) was 20 (0-35.5, p < 0.0001), and 23.5 (5-40, p < 0.0001) for D30 to 365 (D365). The highest percentage of survivors for all mSI groups were home by D365 (G1 55%, G2 88%, G3 84.5%, G4 90%). Median (IQR) EQ VAS scores by mSI quartile, patient disposition and timepoint are reported below. Conclusion: ICH survivors, matching WoLST individuals, in all mSI groups demonstrated improvement in HRQoL over time, and the majority were home by D365. This study challenges current practice of identifying poor outcomes in concert with decision making employing WoLST in ICH. If goals of care are to include return to home and HRQoL, these results strongly suggest that prognostication can be improved. Prospective studies of ICH prognostication and decision making are needed.


2003 ◽  
Vol 21 (18) ◽  
pp. 3502-3511 ◽  
Author(s):  
Fabio Efficace ◽  
Andrew Bottomley ◽  
David Osoba ◽  
Carolyn Gotay ◽  
Henning Flechtner ◽  
...  

Purpose: The aim of this study was to evaluate whether the inclusion of health-related quality of life (HRQOL), as a part of the trial design in a randomized controlled trial (RCT) setting, has supported clinical decision making for the planning of future medical treatments in prostate cancer. Materials and Methods: A minimum standard checklist for evaluating HRQOL outcomes in cancer clinical trials was devised to assess the quality of the HRQOL reporting and to classify the studies on the grounds of their robustness. It comprises 11 key HRQOL issues grouped into four broader sections: conceptual, measurement, methodology, and interpretation. Relevant studies were identified in a number of databases, including MEDLINE and the Cochrane Controlled Trials Register. Both their HRQOL and traditional clinical reported outcomes were systematically analyzed to evaluate their consistency and their relevance for supporting clinical decision making. Results: Although 54% of the identified studies did not show any differences in traditional clinical end points between treatment arms and 17% showed a difference in overall survival, 74% of the studies showed some difference in terms of HRQOL outcomes. One third of the RCTs provided a comprehensive picture of the whole treatment including HRQOL outcomes to support their conclusions. Conclusion: A minimum set of criteria for assessing the reported outcomes in cancer clinical trials is necessary to make informed decisions in clinical practice. Using a checklist developed for this study, it was found that HRQOL is a valuable source of information in RCTs of treatment in metastatic prostate cancer.


2018 ◽  
Vol 178 ◽  
pp. 08014
Author(s):  
Mihail Aurel Ţîţu ◽  
Andrei Victor Sandu ◽  
Costel Ceocea ◽  
Alina Bianca Pop ◽  
Ştefan Ţîţu ◽  
...  

This scientific paper addresses the importance of water treatment process until it becomes drinkable, studying the treatment process from different points of view that are considered to be relevant. The choice of this subject was motivated by the water consumption importance for the entire population, the scientific paper proposing to study in what way this water treatment process could be improved, using for analysis two methods of experimental statistical modeling, namely the Taguchi's method and the factorial experiment method. The purpose of this scientific paper was to identify the deficiencies of the water treatment process after it entered the treatment plant and analyze is carried out using the two mentioned methods above, were continued by finding optimization solutions for the process. These solutions are intended to avoid the situations in which the treatment plant may be unable to cover the required volume of drinking water and to ensure the quality of the drinking water supplied to consumers according to the legislation to date. The knowledge benefit of this research consists in the realization of the research intentions formulated and the practical applicability of the results.


2016 ◽  
Vol 29 (2) ◽  
pp. 119
Author(s):  
Kimberley Haines ◽  
Louisa Remedios ◽  
Sue Berney ◽  
Cameron Knott ◽  
Linda Denehy

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