Modulation of MNC Phenotype and Macrophage Differentiation by the Matrix Elasticity in the Foreign Body Reaction

2020 ◽  
Author(s):  
Josephine Y. Fang ◽  
Zhi Yang ◽  
Wei Hu ◽  
Ba Xuan Hoang ◽  
Bo Han

1988 ◽  
Vol 98 (6) ◽  
pp. 546-551 ◽  
Author(s):  
Etsuo Yamamoto ◽  
Michitaka Iwanaga ◽  
Manabu Fukumoto

We examined conditions of the micro-sliced homograft cartilages implanted in the middle ear, implanted cartilages removed at revision surgery or implanted cartilages removed at the second stage of staged tympanoplasty, both macroscopically and histologically. Macroscopically, the appearance and shape of the cartilages remained unchanged, with no evidence of erosion. There was no evidence of any foreign body reaction or rejection phenomenon. In general, no marked histologic changes of the matrix tissues were found, although chondrocytes showed degenerative changes. There was partial absorption of cartilage and replacement by fibrous connective tissue when inflammatory changes occurred in the middle ear. It is concluded that implanted homograft cartilage maintains its stiffness for more than 6 months in a healthy, aerated middle ear and appears to be clinically useful for tympanoplasty.



1996 ◽  
Vol 16 (1) ◽  
pp. 83-88
Author(s):  
Robert Bendon ◽  
Jim Greenberg ◽  
Sue Heffelfinger




2014 ◽  
Vol 2014 ◽  
pp. 1-2
Author(s):  
Rintaro Shibuya ◽  
Yuichiro Endo ◽  
Akihiro Fujisawa ◽  
Miki Tanioka ◽  
Yoshiki Miyachi

Pencil core granuloma is characterized by a delayed foreign-body reaction against retained fragments of pencil lead. Previous case reports presented pencil core granuloma resembling malignant melanoma, haemangioma, or soft tissue sarcoma. We present a case of pencil core granuloma arising from the palm 25 years after the initial injury. The patient presented a bluish nodule that had been present over 25 years before. The nodule initially measured 5 mm in diameter. However, five years before presentation, it suddenly enlarged to the size of 30 mm during six months. Computed tomography (CT) of the lesion revealed a linear radiopaque structure of 8 mm long with a mass on its distal end. Surgical resection revealed a bluish muddy mass and pencil lead. Histological examination revealed degenerative tissue with calcification surrounded by massive amounts of black granular material in the middle and lower dermis.



2011 ◽  
Vol 102 (9) ◽  
pp. 740-742
Author(s):  
J. Neila ◽  
M. Perea ◽  
J.J. Ríos-Martín ◽  
F.M. Camacho


2011 ◽  
Vol 75 (11) ◽  
pp. 1455-1458 ◽  
Author(s):  
Hye Jin Lim ◽  
Eun-So Lee ◽  
Hun Yi Park ◽  
Keehyun Park ◽  
Yun-Hoon Choung


2007 ◽  
Vol 83A (3) ◽  
pp. 879-886 ◽  
Author(s):  
D.T. Luttikhuizen ◽  
P.Y.W. Dankers ◽  
M.C. Harmsen ◽  
M.J.A. van Luyn


Author(s):  
Dmitry Yu Borin ◽  
Mikhail V Vaganov

Abstract First-order reversal curve (FORC) analysis allows one to investigate composite magnetic materials by decomposing the magnetic response of a whole sample into individual responses of the elementary objects comprising the sample. In this work, we apply this technique to analysing silicone elastomer composites reinforced with ferromagnetic microparticles possessing low intrinsic coercivity. Even though the material of such particles does not demonstrate significant magnetic hysteresis, the soft matrix of the elastomers allows for the translational mobility of the particles and enables their magnetomechanical hysteresis which renders into a wasp-waisted major magnetization loop of the whole sample. It is demonstrated that the FORC diagrams of the composites contain characteristic wing features arising from the collective hysteretic magnetization of the magnetically soft particles. The influence of the matrix elasticity and particle concentration on the shape of the wing feature is investigated, and an approach to interpreting experimental FORC diagrams of the magnetically soft magnetoactive elastomers is proposed. The experimental data are in qualitative agreement with the results of the simulation of the particle magnetization process obtained using a model comprised of two magnetically soft particles embedded in an elastic environment.



Neurology ◽  
1967 ◽  
Vol 17 (4) ◽  
pp. 337-337 ◽  
Author(s):  
T. Yanagihara ◽  
N. P. Goldstein ◽  
H. J. Svien ◽  
R. C. Bahn


2016 ◽  
Vol 43 (1) ◽  
pp. 40-45 ◽  
Author(s):  
Hong Bae Jeon ◽  
Dong Hee Kang ◽  
Ja Hea Gu ◽  
Sang Ah Oh


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