Regulation of Drosophila Visceral Muscle Contractions by Multiple, Indirect Octopaminergic and Glutamatergic Signaling Pathways

2021 ◽  
Author(s):  
Sonali A. Deshpande ◽  
Ethan Rohrbach ◽  
James Asuncion ◽  
Jenna Harrigan ◽  
Aditya Eamani ◽  
...  
Keyword(s):  
Signaling Pathways ◽  
Muscle Contractions ◽  
Visceral Muscle ◽  
Glutamatergic Signaling

scholarly journals Molecular Pathways: Dysregulated Glutamatergic Signaling Pathways in Cancer

2012 ◽  
Vol 18 (16) ◽  
pp. 4240-4246 ◽  
Author(s):  
Todd D. Prickett ◽  
Yardena Samuels
Keyword(s):  
Signaling Pathways ◽  
Molecular Pathways ◽  
Glutamatergic Signaling

scholarly journals High-frequency electrically stimulated skeletal muscle contractions increase p70s6k phosphorylation independent of known IGF-I sensitive signaling pathways

FEBS Letters ◽  
2010 ◽  
Vol 584 (13) ◽  
pp. 2891-2895 ◽  
Author(s):  
Sarah Witkowski ◽  
Richard M. Lovering ◽  
Espen E. Spangenburg
Keyword(s):  
Skeletal Muscle ◽  
Signaling Pathways ◽  
High Frequency ◽  
Muscle Contractions ◽  
Igf I

A compendium of G-protein–coupled receptors and cyclic nucleotide regulation of adipose tissue metabolism and energy expenditure

2020 ◽  
Vol 134 (5) ◽  
pp. 473-512 ◽  
Author(s):  
Ryan P. Ceddia ◽  
Sheila Collins
Keyword(s):  
Adipose Tissue ◽  
Energy Expenditure ◽  
Signaling Pathways ◽  
G Protein ◽  
Uncoupling Protein ◽  
Beige Adipocytes ◽  
Nucleotide Regulation ◽  
Ucp1 Expression ◽  
Thermogenic Adipocytes ◽  
G Protein Coupled

Abstract With the ever-increasing burden of obesity and Type 2 diabetes, it is generally acknowledged that there remains a need for developing new therapeutics. One potential mechanism to combat obesity is to raise energy expenditure via increasing the amount of uncoupled respiration from the mitochondria-rich brown and beige adipocytes. With the recent appreciation of thermogenic adipocytes in humans, much effort is being made to elucidate the signaling pathways that regulate the browning of adipose tissue. In this review, we focus on the ligand–receptor signaling pathways that influence the cyclic nucleotides, cAMP and cGMP, in adipocytes. We chose to focus on G-protein–coupled receptor (GPCR), guanylyl cyclase and phosphodiesterase regulation of adipocytes because they are the targets of a large proportion of all currently available therapeutics. Furthermore, there is a large overlap in their signaling pathways, as signaling events that raise cAMP or cGMP generally increase adipocyte lipolysis and cause changes that are commonly referred to as browning: increasing mitochondrial biogenesis, uncoupling protein 1 (UCP1) expression and respiration.

194: Influence of the Inhibition of Cyclic Nucleotide Phosphodiesterase type 4 on Human Detrusor Smooth Muscle Contractions

2006 ◽  
Vol 175 (4S) ◽  
pp. 63-63 ◽  
Author(s):  
Stephanie Oger ◽  
Delphine Behr-Roussel ◽  
Jacques Bernabe ◽  
Pierre Denys ◽  
Eva Camperat ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Cyclic Nucleotide ◽  
Muscle Contractions ◽  
Cyclic Nucleotide Phosphodiesterase ◽  
Detrusor Smooth Muscle ◽  
Phosphodiesterase Type ◽  
Smooth Muscle Contractions ◽  
Human Detrusor

Cell signaling pathways involved in enhanced cardiac repair mediated by TGF-β treated amnion epithelial cells

2013 ◽  
Vol 61 (S 01) ◽  
Author(s):  
R Roy ◽  
A Brodarac ◽  
H Stachelscheid ◽  
YH Choi ◽  
R Hetzer ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Cell Signaling ◽  
Signaling Pathways ◽  
Cardiac Repair ◽  
Cell Signaling Pathways ◽  
Amnion Epithelial Cells

Action of curcumin and its synthetic analog CDF on cancer related signaling pathways

Planta Medica ◽  
2014 ◽  
Vol 80 (10) ◽  
Author(s):  
P Balachandran ◽  
FH Sarkar ◽  
DS Pasco
Keyword(s):  
Signaling Pathways ◽  
Synthetic Analog
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