Jump Bidding in Online Auctions: An in Vivo Experiment

2021 ◽  
Author(s):  
Joyce Delnoij ◽  
Sarah Rezaei ◽  
Arnout van de Rijt
Keyword(s):  
Online Auctions ◽  
In Vivo Experiment ◽  
Jump Bidding

The Antimicrobial and Tissue Healing Efficacy of the Atmospheric Pressure Cold Plasma on Grade III Infected Pressure Ulcer: Randomized Controlled In Vivo Experiment

2020 ◽  
Author(s):  
Ayşe Akbiyik ◽  
Dilek Sari ◽  
Utku Kürşat Ercan ◽  
Yiğit Uyanikgil ◽  
Hüseyin Taşli ◽  
...  
Keyword(s):  
Pressure Ulcer ◽  
Atmospheric Pressure ◽  
Cold Plasma ◽  
Randomized Controlled ◽  
In Vivo Experiment ◽  
Tissue Healing ◽  
Grade Iii

The Dependence of the Mutagenic Effect on the Dose of X-Ray Irradiation in an In Vivo Experiment on Female (CBA×C57Bl/6)F1 Mice

2018 ◽  
Vol 166 (1) ◽  
pp. 43-45 ◽  
Author(s):  
L. P. Sycheva ◽  
R. A. Shchegoleva ◽  
N. I. Lisina ◽  
A. V. Gordeev ◽  
L. M. Rozhdestvenskii
Keyword(s):  
Mutagenic Effect ◽  
X Ray ◽  
In Vivo Experiment

scholarly journals The Effects of miR-195-5p/MMP14 on Proliferation and Invasion of Cervical Carcinoma Cells Through TNF Signaling Pathway Based on Bioinformatics Analysis of Microarray Profiling

2018 ◽  
Vol 50 (4) ◽  
pp. 1398-1413 ◽  
Author(s):  
Min Li ◽  
Chun-Xia Ren ◽  
Jian-Mei Zhang ◽  
Xiao-Yan Xin ◽  
Teng Hua ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Signaling Pathway ◽  
Microarray Analysis ◽  
Cervical Carcinoma ◽  
Carcinoma Cells ◽  
Gene Set Enrichment Analysis ◽  
Qrt Pcr ◽  
In Vivo Experiment ◽  
Proliferation And Invasion

Background/Aims: This study is aimed at identification of miR-195-5p/MMP14 expression in cervical cancer (CC) and their roles on cell proliferation and invasion profile of CC cells through TNF signaling pathway in CC. Methods: Microarray analysis, gene set enrichment analysis (GSEA) and DAVID were used to analyze differentially expressed miRNAs, mRNAs and signaling pathways. MiR-195-5p and MMP14 expression levels in CC cell were determined by qRT-PCR. Western blot was employed to measure MMP14 and TNF signaling pathway-relating protein level. Luciferase reporter system was used to confirm the targeting relationship between MMP14 and miR-195-5p. Cell proliferation and invasion was respectively deeded by CCK8, transwell. In vivo experiment was carried out to study the impact of MMP14 and miR-195-5p on CC development in mice. Results: The microarray analysis and the results of qRT-PCR determined that miR-195-5p was under-expressed and MMP14 was over-expressed in CC cells. GSEA and DAVID analysis showed that TNF signaling pathway was regulated by miR-195-5p/MMP14 and activated in cervical carcinoma cells. The miR-195-5p and MMP14 have a negative regulation relation. In vivo experiment found that down-regulated MMP14 and up-regulated miR-195-5p suppressed the tumor development. Conclusion: Our results suggest that MMP14 is a direct target of miR-195-5p, and down-regulated MMP14 and up-regulated miR-195-5p suppressed proliferation and invasion of CC cells by inhibiting TNF signaling pathway.

Investigation of the effect of blackcurrant alcohol-based mors in the composition of an alcoholic beverage on the degree of intoxication of laboratory animals with ethyl alcohol

2021 ◽  
pp. 29-31
Author(s):  
Анна Георгиевна Калинина ◽  
Ирина Михайловна Абрамова ◽  
Наталья Евгеньевна Головачёва ◽  
Светлана Семеновна Морозова ◽  
Любовь Павловна Галлямова
Keyword(s):  
Ethyl Alcohol ◽  
Alcoholic Beverage ◽  
Laboratory Animals ◽  
Negative Consequences ◽  
Chronic Intoxication ◽  
In Vivo Experiment

Результаты исследования в опыте in vivo подтвердили снижение негативных последствий при хронической интоксикации животных для образцов настойки сладкой крепостью 20 %, содержащей черносмородиновый спиртованный морс, по сравнению с раствором этилового спирта аналогичной крепости. The results of the study in the in vivo experiment confirmed a reduction in the negative consequences of chronic intoxication of animals for samples of tincture with a sweet strength of 20 %, containing blackcurrant alcoholic mors, compared with a solution of ethyl alcohol of a similar strength.

Cadmium Chloride Induces Memory Deficits and Hippocampal Damage by Activating the JNK/p66Shc/NADPH Oxidase Axis

2020 ◽  
Vol 39 (5) ◽  
pp. 477-490
Author(s):  
Attalla Farag El-kott ◽  
Ali S. Alshehri ◽  
Heba S. Khalifa ◽  
Abd-El-karim M. Abd-Lateif ◽  
Mohammad Ali Alshehri ◽  
...  
Keyword(s):  
Nadph Oxidase ◽  
Cadmium Chloride ◽  
Nicotinamide Adenine Dinucleotide Phosphate ◽  
Male Rats ◽  
Hippocampal Damage ◽  
Vitro Experiment ◽  
In Vitro Experiment ◽  
In Vivo Experiment

This study investigated whether the mechanism underlying the neurotoxic effects of cadmium chloride (CdCl2) in rats involves p66Shc. This study comprised an initial in vivo experiment followed by an in vitro experiment. For the in vivo experiment, male rats were orally administered saline (vehicle) or CdCl2 (0.05 mg/kg) for 30 days. Thereafter, spatial and retention memory of rats were tested and their hippocampi were used for biochemical and molecular analyses. For the in vitro experiment, control or p66Shc-deficient hippocampal cells were treated with CdCl2 (25 µM) in the presence or absence of SP600125, a c-Jun N-terminal kinase (JNK) inhibitor. Cadmium chloride impaired the spatial learning and retention memory of rats; depleted levels of glutathione and manganese superoxide dismutase; increased reactive oxygen species (ROS), tumor necrosis factor α, and interleukin 6; and induced nuclear factor kappa B activation. Cadmium chloride also decreased the number of pyramidal cells in the CA1 region and induced severe damage to the mitochondria and endoplasmic reticulum of cells in the hippocampi of rats. Moreover, CdCl2 increased the total unphosphorylated p66Shc, phosphorylated (Ser36) p66Shc, phosphorylated JNK, nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, cytochrome c, and cleaved caspase-3. A dose–response increase in cell death, ROS, DNA damage, p66Shc, and NADPH oxidase was also observed in cultured hippocampal cells treated with CdCl2. Of note, all of these biochemical changes were attenuated by silencing p66Shc or inhibiting JNK with SP600125. In conclusion, CdCl2 induces hippocampal ROS generation and apoptosis by promoting the JNK-mediated activation of p66Shc.

Minimal Invasive Surgery in Spine, New Development of Injectable Cereamic MBCP for Vertebral Body Bone Filling: In Vivo Experiment

2005 ◽  
pp. 803-806
Author(s):  
Guy Daculsi ◽  
Hugues Mousselard ◽  
Eric Goyenvalle ◽  
Paul Pilet ◽  
Séverine Delplace ◽  
...  
Keyword(s):  
Vertebral Body ◽  
Invasive Surgery ◽  
Minimal Invasive Surgery ◽  
Minimal Invasive ◽  
In Vivo Experiment ◽  
New Development ◽  
Bone Filling ◽  
Body Bone

scholarly journals In Vivo Experiment on the Metabolism of Cesium in Human Blood with Reference to Rubidium and Potassium

1966 ◽  
Vol 7 (1) ◽  
pp. 29-46 ◽  
Author(s):  
Noboru YAMAGATA ◽  
Kiyoshi IWASHIMA ◽  
Teruo NAGAI ◽  
Kazuo WATARI ◽  
Takeshi A. IINUMA
Keyword(s):  
Human Blood ◽  
In Vivo Experiment

Thromboembolic Events with Enterprise Versus Pipeline: Porcine In Vivo Experiment

2019 ◽  
Vol 122 ◽  
pp. e1405-e1411
Author(s):  
Andrew Griffin ◽  
Eduardo Chaparro ◽  
Ekaterina Fedorova ◽  
Christie Holmes ◽  
Roberto J. Manson ◽  
...  
Keyword(s):  
Thromboembolic Events ◽  
In Vivo Experiment

The sialidase inhibitor, DANA, reduces Porphyromonas gingivalis pathogenicity and exerts anti‐inflammatory effects: An in vitro and in vivo experiment

2020 ◽  
Author(s):  
Shiwen Yu ◽  
Xiaomiao Fan ◽  
Shaowen Zheng ◽  
Li Lin ◽  
Jingbo Liu ◽  
...  
Keyword(s):  
Porphyromonas Gingivalis ◽  
In Vivo Experiment ◽  
Sialidase Inhibitor ◽  
Anti Inflammatory
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