Co-expression of CD39 and CD103 identifies tumor-reactive CD8 tumor-infiltrating lymphocytes in human solid tumors

immuneACCESS ◽  
2018 ◽  
Author(s):  
T Duhen ◽  
R Duhen ◽  
R Montler ◽  
J Moses ◽  
T Moudgil ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Tumor Infiltrating Lymphocytes ◽  
Human Solid Tumors ◽  
Infiltrating Lymphocytes

The role of CD4+ tumor-infiltrating lymphocytes in human solid tumors

1995 ◽  
Vol 14 (2) ◽  
pp. 119-131 ◽  
Author(s):  
Peter S. Goedegebuure ◽  
Timothy J. Eberlein
Keyword(s):  
Solid Tumors ◽  
Tumor Infiltrating Lymphocytes ◽  
Human Solid Tumors ◽  
Infiltrating Lymphocytes

Separation of tumor-infiltrating lymphocytes from tumor cells in human solid tumors

1986 ◽  
Vol 90 (2) ◽  
pp. 221-233 ◽  
Author(s):  
Theresa L. Whiteside ◽  
Sylvia Miescher ◽  
H.R. MacDonald ◽  
V. Von Fliedner
Keyword(s):  
Solid Tumors ◽  
Tumor Cells ◽  
Tumor Infiltrating Lymphocytes ◽  
Human Solid Tumors ◽  
Infiltrating Lymphocytes

Role of tumor-infiltrating lymphocytes in patients with solid tumors: Can a drop dig a stone?

2019 ◽  
Vol 343 ◽  
pp. 103753 ◽  
Author(s):  
Giuseppe Badalamenti ◽  
Daniele Fanale ◽  
Lorena Incorvaia ◽  
Nadia Barraco ◽  
Angela Listì ◽  
...  
Keyword(s):  
Solid Tumors ◽  
Tumor Infiltrating Lymphocytes ◽  
Infiltrating Lymphocytes

Abstract 4953: Differential expression of ICOS on circulating immune cells and tumor infiltrating lymphocytes in patient with solid tumors

2019 ◽  
Author(s):  
Richard C. Sainson ◽  
Miha Kosmac ◽  
Rachael Kimber ◽  
Joana Carvalho ◽  
Gwenoline Bohris ◽  
...  
Keyword(s):  
Differential Expression ◽  
Solid Tumors ◽  
Immune Cells ◽  
Tumor Infiltrating Lymphocytes ◽  
Infiltrating Lymphocytes

Multiparameter study of the immunophenotype of tumor infiltrating lymphocytes, in cancer patients

2016 ◽  
Vol 21 (1-2) ◽  
pp. 51-54 ◽  
Author(s):  
Tat’yana N. Zabotina ◽  
O. V Korotkova ◽  
A. A Borunova ◽  
D. V Tabakov ◽  
I. I Bokin ◽  
...  
Keyword(s):  
Flow Cytometry ◽  
Solid Tumors ◽  
Squamous Carcinoma ◽  
Tumor Infiltrating Lymphocytes ◽  
Tissue Level ◽  
Main Role ◽  
Regulatory T Lymphocytes ◽  
The Difference ◽  
Infiltrating Lymphocytes ◽  
First Time

For the first time in Russia the immunophenotype of tumor infiltrated lymphocytes (TIL) was investigated with the use of a method of quantitative flow cytometry. Samples from 104 patients, suffering from solid tumors (such as breast cancer, ovarian cancer, melanoma and oral cavity squamous carcinoma), were analyzed in this investigation. In the difference of cytomorphological analysis, the method of flow cytometry identified TIL in 100% of cases. In the structure of CDS+Т- lymphocytes the ratio CD4/CD8 was equal to 1,1±0,1. Serial gating strategy allowed to assess minor subpopulations of regulatory T-lymphocytes CD45+CD4+CD127+low/neg and CD45+CD8+CD28-CD11b-. Regulatory mechanisms with involvement of CD8 T-cells played the main role in the generation of immune responses at the tissue level ofpatients, suffering from solid tumors, independent of nosological form of disease.

γ/δ T cell antigen receptors expressed on tumor-infiltrating lymphocytes from patients with solid tumors

1992 ◽  
Vol 22 (3) ◽  
pp. 679-687 ◽  
Author(s):  
Masanobu Nanno ◽  
Hidetoshi Seki ◽  
George Mathioudaki ◽  
Ryuzi Suzuki ◽  
Kyogo Itoh ◽  
...  
Keyword(s):  
T Cell ◽  
Solid Tumors ◽  
Tumor Infiltrating Lymphocytes ◽  
Antigen Receptors ◽  
Cell Antigen ◽  
T Cell Antigen Receptors ◽  
Infiltrating Lymphocytes
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