2SB-02 DESIGN, SYNTHESIS AND BIOLOGICAL APPLICATION OF MOLECULAR IMAGING PROBES WITH TUNABLE CHEMICAL SWITCHES(2SB Frontiers in chemical biology for in-cell biophysics,The 49th Annual Meeting of the Biophysical Society of Japan)

2011 ◽  
Vol 51 (supplement) ◽  
pp. S15
Author(s):  
Kazuya Kikuchi
Author(s):  
Rajasekharreddy Pala ◽  
Subhaswaraj Pattnaik ◽  
Yun Zeng ◽  
Siddhardha Busi ◽  
Surya M. Nauli ◽  
...  

2011 ◽  
Vol 10 (6) ◽  
pp. 7290.2011.00003 ◽  
Author(s):  
Fred Reynolds ◽  
Kimberly A. Kelly

Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.


2018 ◽  
Vol 61 (2) ◽  
pp. 68-76 ◽  
Author(s):  
Kusum Vats ◽  
Drishty Satpati ◽  
Rohit Sharma ◽  
Chandan Kumar ◽  
Haladhar Dev Sarma ◽  
...  

2011 ◽  
Vol 51 (supplement) ◽  
pp. S67
Author(s):  
Ryuta Okada ◽  
Katsuo Ichinomiya ◽  
Yasushi Fujimoto ◽  
Katsuyuki Abe ◽  
Yoshihiro Ue ◽  
...  

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