Quality of Life Among Breast Cancer Patients Attending Hawassa University Comprehensive Specialized Hospital Cancer Treatment Center

Abstract Background Breast cancer is the second most prevalent malignancy in Ethiopia and severely affects patients’ health-related quality of life (HRQOL). We aimed to assess HRQoL, factors influencing HRQoL, and utilities among breast cancer patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Methods A hospital-based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital from December 2017 to February, 2018. A total of 404 breast cancer patients were interviewed using the validated Amharic version of the European Organization for Research and Treatment of Cancer module (EORTC QLQ-C30), EORTC QLQ-BR23, and Euro Quality of Life Group’s 5-Domain Questionnaires 5 Levels (EQ-5D-5 L) instruments. Mean scores and mean differences of EORTC- QLQ-C30 and EORTC- QLQ-BR23 were calculated. One-way ANOVA test was employed to determine the significance of mean differences among dependent and independent variables while stepwise multivariate logistic regression was used to identify factors associated with the global quality of life (GQOL). Coefficients and level specific utility values obtained from a hybrid regression model for the Ethiopian population were used to compute utility values of each health state. Data was analyzed using SPSS version 23. Results The mean age of patients was 43.94 ± 11.72 years. The mean score for GQoL and visual analog scale was 59.32 ± 22.94 and 69.94 ± 20.36, respectively while the mean utility score was 0.8 ± 0.25. Predictors of GQoL were stage of cancer (AOR = 7.94; 95% CI: 1.83–34.54), cognitive functioning (AOR = 2.38; 95% CI: 1.32–4.31), pain (AOR = 7.99; 95% CI: 4.62–13.83), financial difficulties (AOR = 2.60; 95% CI: 1.56–4.35), and future perspective (AOR = 2.08; 95% CI: 1.24–3.49). Conclusions The overall GQoL of breast cancer patients was moderate. Targeted approaches to improve patients’ HRQoL should consider stage of cancer, cognitive functioning, pain, financial status and worries about the patient’s future health. This study also provides estimates of EQ-5D utility scores that can be used in economic evaluations.

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Social support and quality of life among female breast cancer patients at Tikur Anbessa Specialized Hospital, Ethiopia 2019:Cross-sectional study

10.21203/rs.3.rs-33300/v1 ◽

2020 ◽

Author(s):

Rahel Aberaraw ◽

Jemal Hussien ◽

Abdisa Boka ◽

Roza Teshome ◽

Addisu Yeshambel

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Social Support ◽

Cancer Patients ◽

Female Breast Cancer ◽

P Value ◽

Breast Cancer Patients ◽

Female Breast ◽

Specialized Hospital

Abstract Background Breast cancer is a major life-threatening public health problem worlwide. It is the most common form of cancer among women in many developing countries including Ethiopia. Social support could change the course of cancer and can influence the quality of life among breast cancer patients. Therefore, purpose of this study was to assess social support and quality of life among female breast cancer patients attending in Tikur Anbassa Specialized Hospital, Addis Ababa, Ethiopia 2019.Methods A Hospital-based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital, Ethiopia from March to April 2019. A total of 214 female breast cancer patients were included and a systematic sampling method was used. A structured and pre-tested questionnaire was used. Data entry was done using epi data manager version 4.2. Data analysis was done using Statistical Package for Social Sciences version 25. Binary and multiple logistic regression was used to show the association of social support and quality of life. Variables significantly associated were declared at P-value <0.05 and 95%CI was used.Result A total of 214 women with breast cancer were recruited. Of the total participants, 124(58%) had good social support. It was found that participants who were college graduated (AOR=3, 95%CI: 1.5, 5.9 COR=3.2) and who had high monthly income(AOR=2.3, 95% CI: 1.2,8.5, COR= 5.39) were more likely to have good social support. It was also found that participants who were illiterate (AOR=3, 95%CI: 1.3,6.9, COR=4.8, p-value=0.008), who had systematic therapy side effects(AOR=3.8, 95%CI: 1.1,13, COR=4, p-value=0.035)and participants who had problem of appetite loss(AOR=3.5, 95%CI: 1.02,12COR=4, p-value= 0.047) were more likely to have affected QoL. Conclusion In this study finding, social support and, quality of life in breast cancer patients was low. Healthcare providers should enhance social support which may help to improve the quality of life of women with breast cancer.

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Social networks and quality of life among female breast cancer patients at Tikur Anbessa Specialzed Hospital, Addis Ababa, Ethiopia 2019

10.21203/rs.2.12540/v1 ◽

2019 ◽

Author(s):

Rahle Aberaraw ◽

Addisu Yeshambel ◽

Abdisa Boka ◽

Roza Teshome

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Social Networks ◽

Cancer Patients ◽

Addis Ababa ◽

Female Breast Cancer ◽

Breast Cancer Patients ◽

Female Breast ◽

Specialized Hospital

Abstract Background Breast cancer is a major life-threatening public health problem in the world. It is the most common form of cancer among women in many developing countries including Ethiopia. Social networks could change the course of cancer and can influence the quality of life among breast cancer patients. Therefore, the purpose of this study was to assess social networks and quality of life among female breast cancer patients attending in Tikur Anbassa Specialized Hospital, Addis Ababa, Ethiopia 2019. Methods An institutional based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital Addis Ababa, Ethiopia from March to April 2019. A total of 214 female breast cancer patients were included and systematic sampling method was used. A structured and pre-tested questionnaire was used. Data entry was done using epi data-manager version 4.2. Data analysis was done using Statistical Package for the Social Sciences version 25. Binary and multiple logistic regression was used to show the association of social networks and quality of life. The strength of association was declared P-value <0.05 and 95%CI was used. Result A total of 214 women with breast cancer were recruited. The mean age was 41.85. Among total participants, 13(6%), 65(30%) and 136(64%) had limited, medium and diverse social networks respectively. Whereas, 198(92.52%) of them had affected quality of life. Participants who were illiterate were more likely to have affected quality of life by 3 times than who were more educated (AOR=3, 95%CI: 1.3,6.9, COR=4.8) and who had systematic therapy side effects were more likely to have affected QoL by 3.8 times than who had no systemic therapy side effect (AOR=3.8, 95%CI: 1.1,13, COR=4). Conclusion and recommendation In this study finding quality of life in breast cancer was low. Healthcare providers especially working at oncology department need to focus on addressing side effects of therapy and social networks which may help to improve quality of life of women with breast cancer.

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Social networks and quality of life among female breast cancer patients at Tikur Anbessa Specialzed Hospital, Addis Ababa, Ethiopia 2019

10.21203/rs.2.12540/v4 ◽

2020 ◽

Author(s):

Rahle Aberaraw ◽

Abdisa Boka ◽

Roza Teshome ◽

Addisu Yeshambel

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Social Networks ◽

Cancer Patients ◽

Addis Ababa ◽

Female Breast Cancer ◽

Breast Cancer Patients ◽

Female Breast ◽

Specialized Hospital

Abstract Background: Breast cancer is a major life-threatening global public health problem. It is the most common form of cancer in females in many developing countries including Ethiopia. Social networks could change the course of cancer and can influence the quality of life among breast cancer patients. Therefore, the purpose of this study was to assess social networks and quality of life among female breast cancer patients attending in Tikur Anbassa Specialized Hospital, Addis Ababa, Ethiopia 2019. Methods: An institutional-based cross-sectional study was conducted in Tikur Anbessa Specialized Hospital Addis Ababa, Ethiopia from March 1 to April 30/2019. A total of 214 female breast cancer patients were included Binary and multiple logistic regression was used to show the association of social networks and quality of life. Result: A total of 214 females with breast cancer were recruited with a mean age of 41.85. Participants who had children (AOR=5, 95%CL: 1.3,21 COR=6), and other relatives (AOR=6, 95%CI: 1.2,30, COR=7), were more likely to have good social networks. Participants who were not married (AOR=0.02, 95%CI: 0.03, 0.28), had no parents living (AOR=0.1, 95%CI: 0.02, 0.4), no close friends (AOR=0.06, 95%CI: 0.01, 0.4), and no neighbors (AOR=0.09, 95%CI: 0.03, 0.5) had poor social networks. Conclusion: The quality of life was relatively low and social networks were found to be poor in women with breast cancer. Health-care providers in oncology departments need to focus on addressing the side effects of therapy and social networks which may help to improve the quality of life of females with breast cancer.

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The Effect of Interpersonal Psychotherapy on Quality of Life Among Breast Cancer Patients With Common Mental health Disorder: A Randomized Control Trial At Tikur Anbessa Specialized Hospital

10.21203/rs.3.rs-602596/v1 ◽

2021 ◽

Author(s):

Winini Belay ◽

Mirgissa Kaba ◽

Wajana Lako Labisso ◽

Wondemagegnehu Tigeneh ◽

Zekariyas Sahle ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Mental Health ◽

Cancer Patients ◽

Interpersonal Psychotherapy ◽

Mental Health Disorder ◽

Breast Cancer Patients ◽

Specialized Hospital ◽

Tikur Anbessa Specialized Hospital

Abstract Purpose: To determine the effect of interpersonal psychotherapy on anxiety, depression, and quality of life among breast cancer patients with mental health disorders at Tikur Anbessa Specialized Hospital, Ethiopia.Methods: A two-arm parallel randomized controlled trial study was conducted among 114 (n=57 intervention, and n= 57 control group) breast cancer patients with common mental health disorder at the oncology center of Tikur Anbessa Specialized Hospital. The hospital anxiety and depression measurement scale was used to assess depression and anxiety disorder and a 30-item quality of life questionnaire was used to assess the quality of life. General Linear Model analysis was done, confounding factors were controlled, and P<0.05 was used to declare statistical significance. Results: Patients in the intervention group showed a significant improvement in the anxiety (coefficient -3.68; 95% CI -5.67,-1.69; P<0.001), depression (coefficient -3.22; 95% CI -4.7,-1.69; P<0.001), physical functioning (coefficient 10.55; 95% CI 3.13, 17.98; P=0.006), health related quality of life (coefficient 21.85; 95% CI 14.1, 29.59; P<0.001), Insomnia (coefficient -19.56; 95% CI -31.87, -7.25; P=0.002), and fatigue (coefficient -11.37; 95% CI -21.49, -1.24; P=0.028) respectively. Conclusions: The adapted Ethiopian version of interpersonal psychotherapy had improved anxiety, depression, and some domains of health-related quality of life. Hence, health programmers should consider incorporating it as a treatment option in oncology centers.Trial registration number: PACTR202011629348967 granted on 20 November 2020 which was retrospectively registered.

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Short and long term impact of financial toxicity on quality of life in the Carolina Breast Cancer study.

Journal of Clinical Oncology ◽

10.1200/jco.2017.35.15_suppl.e18299 ◽

2017 ◽

Vol 35 (15_suppl) ◽

pp. e18299-e18299 ◽

Cited By ~ 3

Author(s):

Jennifer Spencer ◽

Katherine Elizabeth Reeder-Hayes ◽

Laura C Pinheiro ◽

Lisa A. Carey ◽

Andrew F Olshan ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Treatment ◽

Cancer Patients ◽

Cancer Diagnosis ◽

White Women ◽

Financial Burden ◽

Financial Toxicity ◽

Breast Cancer Patients

e18299 Background: High cancer treatment costs are associated with considerable distress and worse outcomes in cancer patients, a phenomenon known as “financial toxicity”. We examined changes in health-related quality of life (HRQoL) among women experiencing financial toxicity after cancer diagnosis compared to cancer patients without financial toxicity in a racially diverse cohort of breast cancer patients. Methods: HRQoL was self-reported at approximately 5 and 25 months post-diagnosis using the Functional Assessment of Cancer Treatment (FACT-G) in a prospective, population-based, cohort study with oversampling of Black and young (<50 years old) women. Women reported on the financial burden of their breast cancer, including whether they had declined or delayed care due to cost or transportation barriers and whether they lost a job, experienced a reduction in household income, or lost insurance coverage after their cancer diagnosis. We assessed changes in HRQoL from 5 to 25 months according to financial toxicity experience. Results: 2,432 women completed 5- and 25-month HRQoL surveys and were included in analyses. Forty-nine percent were non-Hispanic Black and 51% were non-Hispanic White; other minorities were excluded due to small numbers. Overall, 49% of women reported at least one indicator of financial toxicity (59% Black vs. 39% White). Women who reported any financial toxicity had significantly lower scores on the FACT-G at baseline (75.5 vs 87.2, p<0.001) and reported significantly less improvement in HRQoL from 5- to 25-months than women who did not report financial toxicity (incremental difference: +1.4 vs +3.8, p=.01). Black women reported lower overall HRQoL than White women (p=0.03), but impact of financial toxicity on HRQOL was similar among black and white women in stratified analyses. Conclusions: Financial toxicity is associated with lower HRQoL and with less improvement in HRQoL in the two years following breast cancer diagnosis. [Table: see text]

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The effect of psychological group intervention on emotional problems, event impact and quality of life in breast cancer patients under radiotherapy: a pilot study

Journal of Evidence-Based Psychotherapies ◽

10.24193/jebp.2017.2.8 ◽

2017 ◽

Vol 17 (2) ◽

pp. 133-146 ◽

Cited By ~ 2

Author(s):

Mihaela Iancu ◽

◽

Florina Pop ◽

Raluca Ioana Farcaș ◽

Amfiana Gherman ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Pilot Study ◽

Cancer Patients ◽

Group Intervention ◽

Emotional Problems ◽

Breast Cancer Patients

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PSYCHOLOGICAL REHABILITATION AND SCREENING OF EMOTIONAL STRESS IN CANCER PATIENTS

Problems in oncology ◽

10.37469/0507-3758-2017-63-2-316-319 ◽

2017 ◽

Vol 63 (2) ◽

pp. 316-319 ◽

Cited By ~ 2

Author(s):

Valentina Chulkova ◽

Tatyana Semiglazova ◽

Margarita Vagaytseva ◽

Andrey Karitskiy ◽

Yevgeniy Demin ◽

...

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Cancer Patient ◽

Cancer Patients ◽

Emotional Stress ◽

Self Esteem ◽

Breast Cancer Patients ◽

Psychological Study ◽

Psychological Assistance

Psychological rehabilitation is an integral part of rehabilitation of a cancer patient. Psychological rehabilitation is aimed at a patient adaptation in the situation of the disease and improvement his quality of life. Understanding of an oncological disease is extreme and (or) crisis situation and monitoring dynamics of the psychological statement of a patient allows using differentiated approach in the provision of professional psychological assistance. The modified scale of self-esteem level of distress (IPOS) was used for screening of mental and emotional stress of cancer patients. There were selected groups of cancer patients who were most in need of professional psychological assistance. Results of a psychological study of one of these groups - breast cancer patients - are presented.

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