scholarly journals Transarterial Chemoembolization and Sorafenib Combined with Microwave Ablation for Advanced Primary Hepatocellular Carcinoma: A Preliminary Investigation of Safety and Efficacy

2019 ◽  
Vol Volume 11 ◽  
pp. 9939-9950
Author(s):  
Jia-Yan Ni ◽  
Hong-Liang Sun ◽  
Jiang-Hong Luo ◽  
Xiong-Ying Jiang ◽  
Dong Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Transarterial Chemoembolization ◽  
Microwave Ablation ◽  
Preliminary Investigation ◽  
Primary Hepatocellular Carcinoma ◽  
Safety And Efficacy

scholarly journals Clinical Characteristics of Transarterial Chemoembolization in Treatment of Primary Hepatocellular Carcinoma Complicated With Respiratory Distress Syndrome

2020 ◽  
Vol 19 ◽  
pp. 153303382097067
Author(s):  
Ji-Yin Ruan ◽  
Jia-Tian Lin ◽  
Yu Xiong ◽  
Zai-Zhong Chen ◽  
Jun-Hui Chen ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Respiratory Distress Syndrome ◽  
Respiratory Distress ◽  
Hormone Therapy ◽  
Transarterial Chemoembolization ◽  
Clinical Characteristics ◽  
Pathogenic Bacteria ◽  
Distress Syndrome ◽  
Lateral Lobe ◽  
Primary Hepatocellular Carcinoma

Objective: The present study aims to analyze the clinical characteristics and etiology of transarterial chemoembolization (TACE) in the treatment of hepatocellular carcinoma (HCC) complicated with acute respiratory distress syndrome (ARDS), in order to improve the early diagnosis rate and cure rate. Methods: A total of 816 patients with primary HCC received 2,200 TACE treatments from January 2014 to May 2018. Among these patients, 6 patients developed ARDS after TACE. The clinical data, lesion characteristics, laboratory tests, treatment process and prognosis of 6 patients were retrospectively analyzed. Results: The longest lesion diameter ranged within 5.0-10.2 cm (mean: 6.6 cm) in the 6 patients with primary HCC. Among these patients, 4 patients had lesions mainly located in the left lateral lobe of the liver, while 5 patients had no hepatic arteriovenous fistula detected before TACE. Nedaplatin, epirubicin and iodinated oil suspension chemoembolization were used in all 6 patients during TACE, and all of them experienced ARDS symptoms within 24-48 hours after TACE. However, no clear pathogenic bacteria were incubated in the sputum culture after the onset of the disease. Diffused exudative changes of both lungs were found in the chest X-ray, and the oxygenation index (PaO2/FiO2) was within 100-300 mmHg. The symptoms of 6 patients improved after 3-6 days of hormone therapy. Conclusion: In this study, we found that although the incidence of ARDS after TACE was low in the treatment for HCC, the symptoms after onset were serious, and the early hormone therapy may be beneficial to improve the prognosis and reduce mortality. Further research with larger samples is still needed to confirm the pathogenesis of ARDS after TACE in the treatment for HCC.

Combination transarterial chemoembolization and microwave ablation improves local tumor control for 3- to 5-cm hepatocellular carcinoma when compared with transarterial chemoembolization alone

2018 ◽  
Vol 43 (9) ◽  
pp. 2497-2504 ◽  
Author(s):  
Amanda R. Smolock ◽  
Mircea M. Cristescu ◽  
Audrey Hinshaw ◽  
Kaitlin M. Woo ◽  
Shane A. Wells ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Transarterial Chemoembolization ◽  
Microwave Ablation ◽  
Local Tumor Control ◽  
Tumor Control ◽  
Local Tumor
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