scholarly journals Tumor-to-Gland Volume Ratio versus Tumor-to-Breast Ratio as Measured on CBBCT: Possible Predictors of Breast-Conserving Surgery

2021 ◽  
Vol Volume 13 ◽  
pp. 4463-4471
Author(s):  
Jiawei Li ◽  
Guobin Zhong ◽  
Keqiong Wang ◽  
Wei Kang ◽  
Wei Wei
2019 ◽  
Vol 10 (4) ◽  
pp. 668-672
Author(s):  
Tarek Hashem ◽  
Ahmed Morsi ◽  
Ahmed Farahat ◽  
Tarek Zaghloul ◽  
Amira Hamed

2020 ◽  
Vol 47 (6) ◽  
pp. 574-582
Author(s):  
Seok Kyung In ◽  
Yoon Soo Kim ◽  
Ho Sung Kim ◽  
Jin Hyung Park ◽  
Hong Il Kim ◽  
...  

Background Several oncoplastic approaches have been implemented in recent years to enhance cosmetic results and to reduce complications. The round block technique is a volume displacement technique for breast reconstruction after breast-conserving surgery (BCS). However, its indications are currently limited according to tumor location, and its cosmetic results and complications have not been clearly established. We hypothesized that the round block technique could produce favorable cosmetic results without major complications regardless of tumor location or nipple-tumor distance, below a certain resected tumor volume and tumor-breast volume ratio.Methods All breast reconstructions using the round block technique after BCS were included in this analysis. Patients’ data were reviewed retrospectively to investigate complications during follow-up, and clinical photos were used to evaluate cosmetic results. The relationships of tumor location, nipple-tumor distance, tumor volume, and the tumor-breast volume ratio with cosmetic results were investigated.Results In total, 108 breasts were reconstructed. The mean resected tumor volume was 30.2±15.0 mL. The cosmetic score was 4.5±0.6 out of 5. Tumor location, nipple-tumor distance, tumor volume, tumor-breast volume ratio, radiotherapy, and chemotherapy had no significant effects on cosmetic results or complications. There were no major complications requiring reoperation.Conclusions Breast reconstruction using the round block technique after BCS can lead to good cosmetic results without major complications regardless of the tumor location, nipple-tumor distance, radiotherapy, or chemotherapy. Below the maximum tumor volume (79.2 mL) and the maximum tumor-breast volume ratio (14%), favorable results were consistently obtained.


2015 ◽  
Vol 1102 ◽  
pp. 173-182
Author(s):  
Lawrence Gyansah ◽  
A.M. Abd El-Aty

A bstract. This paper investigates the deformation behavior of reinforced fresh bamboo subjected to static-compressive loading condition. Crushing strength test was performed using Uniaxial Compression Machine with maximum loading capacity of 1500 kN. The data is plotted as strength to weight ratio versus height, strength to volume ratio versus height, failure stress versus height, load versus time of failure and load to height ratio versus time of failure. Result shows that increase in height of the fresh reinforced bamboo increases the strength and vice versa. The moisture content also has significant influence on the strength of the fresh reinforced bamboo. The moisture content reduced the strength of the fresh reinforced bamboo by 21.8 %. This percentage is really significant in structural analysis since it can cause catastrophic failure to structures. Concrete is significant in reinforcing bamboo structures for a better strength. The crushing stresses for fresh reinforced bamboo of heights 250 , 210 ,170 , 130 and 90 mm were found to be 26.09 , 25.52 , 24.85 , 21.97 , 21.86 MPa respectively. The failure stress of the bamboo is about say 1.26 M times the weight of the bamboo per square meter. The specific compressive strength which explains the bending moment per kilogram of the bamboo specimen also increases with increases in height. Failure stress to weight ratio decreases with increases with the height of the bamboo. Strength to volume ratio also decreases with increases with the height from the bamboo.


2021 ◽  
Author(s):  
Zhuifeng Guo ◽  
Fan Yang ◽  
Xuwei Lu ◽  
Jiawen Wu ◽  
Chang He ◽  
...  

Abstract Objective: To explore the significance of the prostate central gland to total gland volume ratio in the diagnosis of PSA 4-10ng/ml prostate cancer (PCa) patients. Method: A retrospective analysis was performed on patients who had undergone prostate biopsy in our hospital from July 2015 to December 2020.The anteroposterior, transverse and axial diameters of the prostate and the central prostate gland were measured using multiparametric magnetic resonance imaging (mpMRI). The differences in PSA, f/tPSA, PSAD and PVc/PV between the PCa group and the non-PCa group were compared. ROC curves for PCa and clinically significant PCa (csPCa) diagnosis were drawn according to PSA, f/tPSA, PSAD and PVc/PV respectively. Corresponding PSA was used as the reference standard for comparison.Results: There was no statistically significant difference in PSA and f/tPSA between the two groups (P>0.05), while there were statistically significant differences in PSAD and PVc/PV between the two groups (P<0.05). By comparing the AUC values of the ROC curve for any PCa or csPCa, the AUC value of PVc/PV was 0.876 and 0.933, and PSAD was 0.705 and 0.790. This is significantly different from that of the PSA curve (P<0.05), whereas f/tPSA was 0.589 and 0.692 showing no significant difference from the PSA curve (P>0.05).Conclusion: Low volume ratio of central prostate gland PVc/PV has a higher incidence of PCa and csPCa, which can be used as an important reference index for the diagnosis of PCa in PSA 4-10 ng/ml patients.


2020 ◽  
Vol 47 (6) ◽  
pp. 583-589
Author(s):  
Min Wook Kim ◽  
Won Seok Oh ◽  
Jae Woo Lee ◽  
Hyun Yul Kim ◽  
Youn Joo Jung ◽  
...  

Background Reduction mammoplasty or mastopexy is performed as an additional balancing procedure in patients with large or ptotic breasts who undergo breast-conserving surgery (BCS). Radiation therapy on breasts that have undergone surgery may result in changes in the volume. This study presents a comparative analysis of patients who received post-BCS balancing procedures to determine whether volume changes were larger in breasts that received radiation therapy than on the contralateral side.Methods Thirty-six participants were selected among patients who received BCS using the inverted-T scar technique between September 2012 and July 2017, were followed up for 2 or more years, and had pre-radiation therapy computed tomography images and post-radiation therapy images taken between 12 and 18 months after completion. The average age of the participants was 53.5 years, their average body mass index was 26.62 kg/m<sup>2</sup>.Results The pre- and post-radiation therapy volumes of the breasts receiving BCS were 666.08±147.48 mL and 649.33±130.35 mL, respectively. In the contralateral breasts, the volume before radiation therapy was 637.69±145.72 mL, which decreased to 628.14±166.41 mL after therapy. The volume ratio of the affected to the contralateral breasts was 1.05±0.10 before radiation therapy and 1.06±0.12 after radiation therapy.Conclusions The ratio of the volume between the two breasts immediately after surgery and at roughly 18 months postoperatively was not significantly different (P=0.98). For these reasons, we recommend a simultaneous single-stage balancing procedure as a reasonable option for patients who require radiation therapy after BCS without concerns regarding volume change.


Diagnostics ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 204
Author(s):  
Andrea Cozzi ◽  
Simone Schiaffino ◽  
Gianmarco Della Pepa ◽  
Serena Carriero ◽  
Veronica Magni ◽  
...  

The tumour-to-breast volume ratio (TBVR) is a metric that may help surgical decision making. In this retrospective Ethics-Committee–approved study, we assessed the correlation between magnetic resonance imaging (MRI)-derived TBVR and the performed surgery. The TBVR was obtained using a fully manual method for the segmentation of the tumour volume (TV) and a growing region semiautomatic method for the segmentation of the whole breast volume (WBV). Two specifically-trained residents (R1 and R2) independently segmented T1-weighted datasets of 51 cancer cases in 51 patients (median age 57 years). The intraobserver and interobserver TBVR reproducibility were calculated. Mann-Whitney U, Spearman correlations, and Bland-Altman statistics were used. Breast-conserving surgery (BCS) was performed in 31/51 cases (61%); mastectomy was performed in 20/51 cases (39%). The median TBVR was 2.08‰ (interquartile range 0.70–9.13‰) for Reader 1, and 2.28‰ (interquartile range 0.71–9.61‰) for Reader 2, with an 84% inter-reader reproducibility. The median segmentation times were 54 s for the WBV and 141 s for the TV. Significantly-lower TBVR values were observed in the breast-conserving surgery group (median 1.14‰, interquartile range 0.49–2.55‰) than in the mastectomy group (median 10.52‰, interquartile range 2.42–14.73‰) for both readers (p < 0.001). Large scale prospective studies are needed in order to validate MRI-derived TBVR as a predictor of the type of breast surgery.


2021 ◽  
Vol 49 (7) ◽  
pp. 030006052110198
Author(s):  
Zhui-Feng Guo ◽  
Fan Yang ◽  
Xu-Wei Lu ◽  
Jia-Wen Wu ◽  
Chang He ◽  
...  

Objective To explore the significance of the prostate central gland to total gland volume ratio (PVc/PV) in the diagnosis of prostate cancer (PCa) in patients with prostate specific antigen (PSA) levels in the grey zone (4–10 ng/ml). Methods This retrospective study enrolled patients that had undergone prostate biopsy. The volume of the prostate and the central prostate gland were measured. The differences in PSA, the ratio of free to total PSA (f/tPSA), PSA density (PSAD) and PVc/PV between the PCa and non-PCa groups were compared. Receiver operating characteristic curve analysis for PCa and clinically significant PCa (csPCa) diagnosis were calculated according to PSA (reference), f/tPSA, PSAD and PVc/PV. Results This study enrolled 136 patients. There was no significant difference in PSA and f/tPSA between the PCa and non-PCa groups, while there were significant differences in PSAD and PVc/PV. The area under the curve values of PVc/PV for PCa or csPCa diagnosis were 0.876 and 0.933, respectively; and for PSAD, they were 0.705 and 0.790, respectively. These were significantly different compared with the PSA curve, whereas f/tPSA showed no significant difference from the PSA curve. Conclusion PVc/PV could be a predictor of PCa when PSA is between 4–10 ng/ml.


Author(s):  
H. Mori ◽  
Y. Murata ◽  
H. Yoneyama ◽  
H. Fujita

Recently, a new sort of nano-composites has been prepared by incorporating such fine particles as metal oxide microcrystallites and organic polymers into the interlayer space of montmorillonite. Owing to their extremely large specific surface area, the nano-composites are finding wide application[1∼3]. However, the topographic features of the microstructures have not been elucidated as yet In the present work, the microstructures of iron oxide-pillared montmorillonite have been investigated by high-resolution transmission electron microscopy.Iron oxide-pillared montmorillonite was prepared through the procedure essentially the same as that reported by Yamanaka et al. Firstly, 0.125 M aqueous solution of trinuclear acetato-hydroxo iron(III) nitrate, [Fe3(OCOCH3)7 OH.2H2O]NO3, was prepared and then the solution was mixed with an aqueous suspension of 1 wt% clay by continuously stirring at 308 K. The final volume ratio of the latter aqueous solution to the former was 0.4. The clay used was sodium montmorillonite (Kunimine Industrial Co.), having a cation exchange capacity of 100 mequiv/100g. The montmorillonite in the mixed suspension was then centrifuged, followed by washing with deionized water. The washed samples were spread on glass plates, air dried, and then annealed at 673 K for 72 ks in air. The resultant film products were approximately 20 μm in thickness and brown in color.


2007 ◽  
Vol 177 (4S) ◽  
pp. 568-568 ◽  
Author(s):  
Jack Groskopf ◽  
Ina L. Deras ◽  
Amy Blase ◽  
Sheila M.J. Aubin ◽  
Seongjoon Koo ◽  
...  

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