Dependability of Automated Breast Ultrasound (ABUS) in Assessing Breast Imaging Reporting and Data System (BI-RADS) Category and Size of Malignant Breast Lesions Compared with Handheld Ultrasound (HHUS) and Mammography (MG)

Abstract Objective The FUSION-X-US-II prototype was developed to combine 3D automated breast ultrasound (ABUS) and digital breast tomosynthesis in a single device. We evaluated the performance of ABUS and tomosynthesis in a single examination in a clinical setting. Methods In this prospective feasibility study, digital breast tomosynthesis and ABUS were performed using the FUSION-X-US-II prototype without any change of the breast position in patients referred for clarification of breast lesions with an indication for tomosynthesis. The tomosynthesis and ABUS images of the prototype were interpreted independently from the clinical standard by a breast diagnostics specialist. Any detected lesion was classified using BI-RADS® scores, and results of the standard clinical routine workup (gold standard) were compared to the result of the separate evaluation of the prototype images. Image quality was rated subjectively and coverage of the breast was measured. Results One hundred one patients received both ABUS and tomosynthesis using the prototype. The duration of the additional ABUS acquisition was 40 to 60 s. Breast coverage by ABUS was approximately 80.0%. ABUS image quality was rated as diagnostically useful in 86 of 101 cases (85.1%). Thirty-three of 34 malignant breast lesions (97.1%) were identified using the prototype. Conclusion The FUSION-X-US-II prototype allows a fast ABUS scan in combination with digital breast tomosynthesis in a single device integrated in the clinical workflow. Malignant breast lesions can be localized accurately with direct correlation of ABUS and tomosynthesis images. The FUSION system shows the potential to improve breast cancer screening in the future after further technical improvements. Key Points • The FUSION-X-US-II prototype allows the combination of automated breast ultrasound and digital breast tomosynthesis in a single device without decompression of the breast. • Image quality and coverage of ABUS are sufficient to accurately detect malignant breast lesions. • If tomosynthesis and ABUS should become part of breast cancer screening, the combination of both techniques in one device could offer practical and logistic advantages. To evaluate a potential benefit of a combination of ABUS and tomosynthesis in screening-like settings, further studies are needed.

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Application of a shear-wave elastography prediction model to distinguish between benign and malignant breast lesions and the adjustment of ultrasound Breast Imaging Reporting and Data System classifications

Clinical Radiology ◽

10.1016/j.crad.2021.10.016 ◽

2021 ◽

Author(s):

Y. Yu ◽

X. Ye ◽

J. Yang ◽

L. Chen ◽

M. Zhang ◽

...

Keyword(s):

Prediction Model ◽

Shear Wave ◽

Breast Imaging ◽

Shear Wave Elastography ◽

Data System ◽

Breast Lesions ◽

Malignant Breast

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Diagnostic Performance of Automated Breast Ultrasound in Differentiating Benign and Malignant Breast Masses in Asymptomatic Women: A Comparison Study With Handheld Ultrasound

Journal of Ultrasound in Medicine ◽

10.1002/jum.14991 ◽

2019 ◽

Vol 38 (11) ◽

pp. 2871-2880 ◽

Cited By ~ 4

Author(s):

Lin Niu ◽

Lingyun Bao ◽

Luoqian Zhu ◽

Yanjuan Tan ◽

Xiaojing Xu ◽

...

Keyword(s):

Diagnostic Performance ◽

Breast Ultrasound ◽

Comparison Study ◽

Breast Masses ◽

Malignant Breast ◽

Handheld Ultrasound ◽

Automated Breast Ultrasound ◽

Asymptomatic Women

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Magnetic Resonance Imaging Texture Analysis in Differentiating Benign and Malignant Breast Lesions of Breast Imaging Reporting and Data System 4

Journal of Computer Assisted Tomography ◽

10.1097/rct.0000000000000969 ◽

2020 ◽

Vol 44 (1) ◽

pp. 83-89

Author(s):

Yanfang Wang ◽

Xing Liao ◽

Feng Xiao ◽

Hanfei Zhang ◽

Jianyu Li ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Magnetic Resonance ◽

Texture Analysis ◽

Breast Imaging ◽

Data System ◽

Breast Lesions ◽

Resonance Imaging ◽

Malignant Breast

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Automated breast ultrasound system (ABUS): can it replace mammography as a screening tool?

Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1186/s43055-019-0051-6 ◽

2019 ◽

Vol 50 (1) ◽

Author(s):

Yasser I. Abd Elkhalek ◽

Ahmed M. Bassiouny ◽

Rasha Wessam Abdel Rahman Abdel Hamid

Keyword(s):

Breast Tissue ◽

Screening Tool ◽

Ultrasound Examination ◽

Breast Ultrasound ◽

Alternative Methods ◽

Breast Lesions ◽

Age Group ◽

Handheld Ultrasound ◽

Ultrasound System ◽

Automated Breast Ultrasound

Abstract Background Mammography is the most accepted, accurate, and effective modality in screening of breast cancer, yet its sensitivity is affected by the density of the breast tissue. Alternative methods for screening are the sonography and MRI but both had their limitations. A new option named ABUS (automated breast ultrasound system) is now proposed to overcome the breast US limitation as it is time-consuming and operator-dependent and to overcome the costly time-consuming MRI. The objectives of the study are to evaluate the accuracy of ABUS in the detection of different breast lesions as a substitution for mammography. This prospective study included 25 women outreached for digital mammography or handheld ultrasound examination at the period between January 2017 and February 2018. Women have no specific age group. Results Significant improvement in the detection of breast lesions by ABUS use with mammogram especially in dense breasts (ACR class C and D) Conclusion ABUS is a promising competitor to mammogram in screening of breast lesions

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Comparison of handheld ultrasound and automated breast ultrasound in women recalled after mammography screening

Acta Radiologica ◽

10.1177/0284185116665421 ◽

2016 ◽

Vol 58 (5) ◽

pp. 515-520 ◽

Cited By ~ 7

Author(s):

Roxanna Hellgren ◽

Paul Dickman ◽

Karin Leifland ◽

Ariel Saracco ◽

Per Hall ◽

...

Keyword(s):

Breast Cancer ◽

Mammography Screening ◽

Breast Ultrasound ◽

Breast Volume ◽

Large Area ◽

Mammographic Finding ◽

Automated Breast Volume Scanner ◽

Handheld Ultrasound ◽

Study Population ◽

Automated Breast Ultrasound

Background Automated breast volume scanner (ABVS) is an ultrasound (US) device with a wide scanner that sweeps over a large area of the breast and the acquired transverse images are sent to a workstation for reconstruction and review. Whether ABVS is as reliable as handheld US is, however, still not established. Purpose To compare the sensitivity and specificity of ABVS to handheld breast US for detection of breast cancer, in the situation of recall after mammography screening. Material and Methods A total of 113 women, five with bilateral suspicious findings, undergoing handheld breast US due to a suspicious mammographic finding in screening, underwent additional ABVS. The methods were assessed for each breast and each detected lesion separately and classified into two categories: breasts with mammographic suspicion of malignancy and breasts with a negative mammogram. Results Twenty-six cancers were found in 25 women. In the category of breasts with a suspicious mammographic finding (n = 118), the sensitivity of both handheld US and ABVS was 88% (22/25). The specificity of handheld US was 93.5% (87/93) and ABVS was 89.2% (83/93). In the category of breasts with a negative mammography (n = 103), the sensitivity of handheld US and ABVS was 100% (1/1). The specificity of handheld US was 100% (102/102) and ABVS was 94.1% (96/102). Conclusion ABVS can potentially replace handheld US in the investigation of women recalled from mammography screening due to a suspicious finding. Due to the small size of our study population, further investigation with larger study populations is necessary before the implementation of such practice.

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