scholarly journals Regulatory Effects of Damaged Renal Epithelial Cells After Repair by Porphyra yezoensis Polysaccharides with Different Sulfation Degree on the Calcium Oxalate Crystal–Cell Interaction

2021 ◽  
Vol Volume 16 ◽  
pp. 8087-8102
Author(s):  
Xin-Yuan Sun ◽  
Hui Zhang ◽  
Ji-Wang Deng ◽  
Bang-Xian Yu ◽  
Yi-Han Zhang ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Calcium Oxalate ◽  
Porphyra Yezoensis ◽  
Cell Interaction ◽  
Calcium Oxalate Crystal ◽  
Renal Epithelial Cells ◽  
Crystal Cell ◽  
Regulatory Effects

scholarly journals MP03-10 EFFECT OF A BACTERIAL URINARY INFECTION ISOLATE ON CALCIUM OXALATE CRYSTAL ADHERENCE TO RENAL EPITHELIAL CELLS

2019 ◽  
Vol 201 (Supplement 4) ◽  
Author(s):  
Jennifer Bjazevic* ◽  
Kaitlin F. Al ◽  
Jaswanth Gorla ◽  
Hassan Razvi ◽  
Jeremy P. Burton
Keyword(s):  
Epithelial Cells ◽  
Calcium Oxalate ◽  
Urinary Infection ◽  
Calcium Oxalate Crystal ◽  
Renal Epithelial Cells ◽  
Crystal Adherence

scholarly journals Protective Effect of Degraded Porphyra yezoensis Polysaccharides on the Oxidative Damage of Renal Epithelial Cells and on the Adhesion and Endocytosis of Nanocalcium Oxalate Crystals

2021 ◽  
Vol 2021 ◽  
pp. 1-15
Author(s):  
Qian-Long Peng ◽  
Chuang-Ye Li ◽  
Yao-Wang Zhao ◽  
Xin-Yuan Sun ◽  
Hong Liu ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Epithelial Cells ◽  
Oxidative Damage ◽  
Protective Effect ◽  
Calcium Oxalate ◽  
Kidney Stone ◽  
Stone Formation ◽  
Porphyra Yezoensis ◽  
Renal Epithelial Cells ◽  
Kidney Stone Formation

The protective effects of Porphyra yezoensis polysaccharides (PYPs) with molecular weights of 576.2 (PYP1), 105.4 (PYP2), 22.47 (PYP3), and 3.89 kDa (PYP4) on the oxidative damage of human kidney proximal tubular epithelial (HK-2) cells and the differences in adherence and endocytosis of HK-2 cells to calcium oxalate monohydrate crystals before and after protection were investigated. Results showed that PYPs can effectively reduce the oxidative damage of oxalic acid to HK-2 cells. Under the preprotection of PYPs, cell viability increased, cell morphology improved, reactive oxygen species levels decreased, mitochondrial membrane potential increased, S phase cell arrest was inhibited, the cell apoptosis rate decreased, phosphatidylserine exposure reduced, the number of crystals adhered to the cell surface reduced, but the ability of cells to endocytose crystals enhanced. The lower the molecular weight, the better the protective effect of PYP. The results in this article indicated that PYPs can reduce the risk of kidney stone formation by protecting renal epithelial cells from oxidative damage and reducing calcium oxalate crystal adhesion, and PYP4 with the lowest molecular weight may be a potential drug for preventing kidney stone formation.

scholarly journals Gallotannin Suppresses Calcium Oxalate Crystal Binding and Oxalate-Induced Oxidative Stress in Renal Epithelial Cells

2012 ◽  
Vol 35 (4) ◽  
pp. 539-544 ◽  
Author(s):  
Hyo-Jung Lee ◽  
Soo-Jin Jeong ◽  
Moon Nyeo Park ◽  
Michael Linnes ◽  
Hee Jeoung Han ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Epithelial Cells ◽  
Calcium Oxalate ◽  
Calcium Oxalate Crystal ◽  
Renal Epithelial Cells ◽  
Crystal Binding

Aqueous extract of Costus arabicus inhibits calcium oxalate crystal growth and adhesion to renal epithelial cells

Urolithiasis ◽  
2015 ◽  
Vol 43 (2) ◽  
pp. 119-124 ◽  
Author(s):  
Mitra R. de Cógáin ◽  
Michael P. Linnes ◽  
Hyo Jung Lee ◽  
Amy E. Krambeck ◽  
Julio Cezar de Mendonça Uchôa ◽  
...  
Keyword(s):  
Crystal Growth ◽  
Epithelial Cells ◽  
Calcium Oxalate ◽  
Aqueous Extract ◽  
Calcium Oxalate Crystal ◽  
Renal Epithelial Cells
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