scholarly journals Liposomes functionalized to overcome the blood–brain barrier and to target amyloid-β peptide: the chemical design affects the permeability across an in vitro model

2013 ◽  
pp. 1749 ◽  
Author(s):  
Francesca Re ◽  
Salvati ◽  
Sesana ◽  
Cambianica ◽  
Giulio Sancini ◽  
...  
Keyword(s):  
Amyloid Beta ◽  
In Vitro Model ◽  
Brain Barrier ◽  
Amyloid Beta Peptide ◽  
Beta Peptide ◽  
Chemical Design ◽  
Vitro Model

Fluorescent amyloid β-peptide ligand derivatives as potential diagnostic tools for Alzheimer’s disease

2013 ◽  
Vol 85 (9) ◽  
pp. 1813-1823 ◽  
Author(s):  
Cristina Airoldi ◽  
Francisco Cardona ◽  
Erika Sironi ◽  
Laura Colombo ◽  
Mario Salmona ◽  
...  
Keyword(s):  
In Vitro Model ◽  
Peptide Ligands ◽  
Amyloid Beta Peptide ◽  
Diagnostic Tools ◽  
Peptide Ligand ◽  
Binding Ability ◽  
Amyloid Peptides ◽  
Beta Peptide ◽  
Vitro Model

Aβ-peptide ligands based on a cis-glycofused benzopyran structure have been fluorescently labeled using coumarine derivatives. Among the synthesized compounds, two conserved their binding ability to β-amyloid peptides, as shown by NMR experiments. Moreover, exploiting its fluorescent property, it was demonstrated that one of such compounds was able to cross an in vitro model of blood–brain barrier (BBB) and to stain Aβ‑deposits.

Permeability of an In Vitro Model of Blood Brain Barrier (BBB)

2009 ◽  
pp. 81-84 ◽  
Author(s):  
Rashid Amin ◽  
Temiz A. Artmann ◽  
Gerhard Artmann ◽  
Philip Lazarovici ◽  
Peter I. Lelkes
Keyword(s):  
Blood Brain Barrier ◽  
In Vitro Model ◽  
Brain Barrier ◽  
Blood Brain ◽  
Vitro Model

A Neurovascular Blood–Brain Barrier In Vitro Model

2014 ◽  
pp. 403-413 ◽  
Author(s):  
Christoph M. Zehendner ◽  
Robin White ◽  
Jana Hedrich ◽  
Heiko J. Luhmann
Keyword(s):  
Blood Brain Barrier ◽  
In Vitro Model ◽  
Brain Barrier ◽  
Blood Brain ◽  
Vitro Model

Dynamic In Vitro Model of the Blood–Brain Barrier: Gene Profiling Using cDNA Microarray Analysis

2003 ◽  
pp. 419-434 ◽  
Author(s):  
Matteo Marroni ◽  
Kelly M. Kight ◽  
Mohammed Hossain ◽  
Luca Cucullo ◽  
Shailesh Y. Desai ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
Microarray Analysis ◽  
Cdna Microarray ◽  
In Vitro Model ◽  
Gene Profiling ◽  
Brain Barrier ◽  
Cdna Microarray Analysis ◽  
Blood Brain ◽  
Vitro Model

scholarly journals A Reconfigurable In Vitro Model for Studying the Blood–Brain Barrier

2019 ◽  
Vol 48 (2) ◽  
pp. 780-793 ◽  
Author(s):  
Monica L. Moya ◽  
Michael Triplett ◽  
Melinda Simon ◽  
Javier Alvarado ◽  
Ross Booth ◽  
...  
Keyword(s):  
Blood Brain Barrier ◽  
In Vitro Model ◽  
Brain Barrier ◽  
Blood Brain ◽  
Vitro Model
Sign in / Sign up

Export Citation Format

Share Document