scholarly journals Determining Persistence with an Inhaled Corticosteroid in Asthma: Assessment Using an Objective Measurement vs the Self-Reported Foster Score

2022 ◽  
Vol Volume 15 ◽  
pp. 25-33
Author(s):  
Britt Overgaard Hedegaard ◽  
Kjell Erik Julius Håkansson ◽  
Frodi Fridason Jensen ◽  
Charlotte Suppli Ulrik ◽  
Ulla Møller Weinreich
2018 ◽  
Vol 10 (5) ◽  
pp. 97 ◽  
Author(s):  
Hilal Al Shamsi ◽  
Abdullah Almutairi

Background: Health specialists and researchers usually collect information about chronic diseases from self-reports. However, the accuracy of self-reports has been questioned as it relies on the respondents’ understanding of pathological conditions and their ability to recall information. Accordingly, an objective diagnosis is generally regarded as a more precise indication of the presence of disease.Objective: The study objectives were to determine the extent of disagreement between self-reporting and objective diagnosis, identify contributory factors to the discrepancy, and examine the effects of the incongruity on quality of healthcare services and health status.Methods: Secondary data from the most recent Oman World Health Survey (OWHS), for which data were readily available (2008), were analysed in the current study. This was the most recent survey conducted in Oman to date as collection of the data for the subsequent survey only commenced in February 2017 and is still in progress. Agreement between the self-reporting of chronic disease (diabetes mellitus and hypertension) and the results of medical examinations was calculated using kappa (ϰ) statistics. Sociodemographic risk factors for the self-reported and objective measurement of disease were identified (second objective). Univariate analysis was measured initially to determine associations between the variables and the outcome. Thereafter, significant variables were included in multivariate analysis performed using logistic regression. The impact of disagreement on quality of healthcare service and health status (third objective) was also examined using the chi-square test in relation to health service quality and health status variables.Results: Of 3524 Oman adults, aged ≥ 20 years (48% males), agreement between the self-reported and objective measurement of chronic disease was found to be poor to moderate (ϰ = 0.001-0.141). The highest agreement was observed for diabetes mellitus (ϰ = 0.402) and the lowest was found for asthma (ϰ = 0.000). Socioeconomic or demographic characteristics were not significantly associated with the degree of agreement attained between the methods used to measure chronic disease (p = > 0.050), except for sex, age and region. The discrepancy did not significantly impact on familial support (i.e., financial, social, health, physical and personal), the responsiveness of the health system, and household income or expenditure. However, the disagreement was associated with significant effects for other healthcare service and health status variables, i.e., quality of life and health service utilisation (p = < 0.050). It was found that people with the chronic disease and aware of their health status (positive agreement), and those with negative objective measure but positive self-reported disease (negative disagreement), were more likely to access healthcare services (83% of who had a positive agreement for chronic lung disease) and to be satisfied with the quality of care provided (82% of who had a negative disagreement for hypertension), compared to those who assumed they were healthy but had a chronic disease.Conclusions and Recommendations: Although agreement between the self-reported and objective measurement of chronic disease was found to be poor to moderate, we found that some socioeconomic demographic characteristics, such as educational and economic level, did not affect the agreement of measure tools for hypertension and diabetes, except for sex, age and region. Contrary to our expectations, disagreement between objective and self-reported measures in chronic diseases appears not to significantly impact on the quality of healthcare services and health status. The high use of health care services in participants with positive disagreement may result in unnecessary healthcare service costs required to treat chronic diseases. The implications on health services use and planning of this disagreement in the diagnosis of chronic diseases have been scarcely addressed in the literature, therefore, the results from our study need to be taken as a first approximation to this issue. Provided the unexpected results, we recommend examining closely the integrity of the dataset before giving full value about the validity of them.


2019 ◽  
Vol 42 ◽  
Author(s):  
Lucio Tonello ◽  
Luca Giacobbi ◽  
Alberto Pettenon ◽  
Alessandro Scuotto ◽  
Massimo Cocchi ◽  
...  

AbstractAutism spectrum disorder (ASD) subjects can present temporary behaviors of acute agitation and aggressiveness, named problem behaviors. They have been shown to be consistent with the self-organized criticality (SOC), a model wherein occasionally occurring “catastrophic events” are necessary in order to maintain a self-organized “critical equilibrium.” The SOC can represent the psychopathology network structures and additionally suggests that they can be considered as self-organized systems.


Author(s):  
M. Kessel ◽  
R. MacColl

The major protein of the blue-green algae is the biliprotein, C-phycocyanin (Amax = 620 nm), which is presumed to exist in the cell in the form of distinct aggregates called phycobilisomes. The self-assembly of C-phycocyanin from monomer to hexamer has been extensively studied, but the proposed next step in the assembly of a phycobilisome, the formation of 19s subunits, is completely unknown. We have used electron microscopy and analytical ultracentrifugation in combination with a method for rapid and gentle extraction of phycocyanin to study its subunit structure and assembly.To establish the existence of phycobilisomes, cells of P. boryanum in the log phase of growth, growing at a light intensity of 200 foot candles, were fixed in 2% glutaraldehyde in 0.1M cacodylate buffer, pH 7.0, for 3 hours at 4°C. The cells were post-fixed in 1% OsO4 in the same buffer overnight. Material was stained for 1 hour in uranyl acetate (1%), dehydrated and embedded in araldite and examined in thin sections.


Author(s):  
Xiaorong Zhu ◽  
Richard McVeigh ◽  
Bijan K. Ghosh

A mutant of Bacillus licheniformis 749/C, NM 105 exhibits some notable properties, e.g., arrest of alkaline phosphatase secretion and overexpression and hypersecretion of RS protein. Although RS is known to be widely distributed in many microbes, it is rarely found, with a few exceptions, in laboratory cultures of microorganisms. RS protein is a structural protein and has the unusual properties to form aggregate. This characteristic may have been responsible for the self assembly of RS into regular tetragonal structures. Another uncommon characteristic of RS is that enhanced synthesis and secretion which occurs when the cells cease to grow. Assembled RS protein with a tetragonal structure is not seen inside cells at any stage of cell growth including cells in the stationary phase of growth. Gel electrophoresis of the culture supernatant shows a very large amount of RS protein in the stationary culture of the B. licheniformis. It seems, Therefore, that the RS protein is cotranslationally secreted and self assembled on the envelope surface.


2020 ◽  
Vol 29 (4) ◽  
pp. 2097-2108
Author(s):  
Robyn L. Croft ◽  
Courtney T. Byrd

Purpose The purpose of this study was to identify levels of self-compassion in adults who do and do not stutter and to determine whether self-compassion predicts the impact of stuttering on quality of life in adults who stutter. Method Participants included 140 adults who do and do not stutter matched for age and gender. All participants completed the Self-Compassion Scale. Adults who stutter also completed the Overall Assessment of the Speaker's Experience of Stuttering. Data were analyzed for self-compassion differences between and within adults who do and do not stutter and to predict self-compassion on quality of life in adults who stutter. Results Adults who do and do not stutter exhibited no significant differences in total self-compassion, regardless of participant gender. A simple linear regression of the total self-compassion score and total Overall Assessment of the Speaker's Experience of Stuttering score showed a significant, negative linear relationship of self-compassion predicting the impact of stuttering on quality of life. Conclusions Data suggest that higher levels of self-kindness, mindfulness, and social connectedness (i.e., self-compassion) are related to reduced negative reactions to stuttering, an increased participation in daily communication situations, and an improved overall quality of life. Future research should replicate current findings and identify moderators of the self-compassion–quality of life relationship.


2012 ◽  
Vol 21 (4) ◽  
pp. 136-143
Author(s):  
Lynn E. Fox

Abstract The self-anchored rating scale (SARS) is a technique that augments collaboration between Augmentative and Alternative Communication (AAC) interventionists, their clients, and their clients' support networks. SARS is a technique used in Solution-Focused Brief Therapy, a branch of systemic family counseling. It has been applied to treating speech and language disorders across the life span, and recent case studies show it has promise for promoting adoption and long-term use of high and low tech AAC. I will describe 2 key principles of solution-focused therapy and present 7 steps in the SARS process that illustrate how clinicians can use the SARS to involve a person with aphasia and his or her family in all aspects of the therapeutic process. I will use a case study to illustrate the SARS process and present outcomes for one individual living with aphasia.


2017 ◽  
Vol 2 (9) ◽  
pp. 3-9 ◽  
Author(s):  
Kristina M. Blaiser ◽  
Mary Ellen Nevins

Interprofessional collaboration is essential to maximize outcomes of young children who are Deaf or Hard-of-Hearing (DHH). Speech-language pathologists, audiologists, educators, developmental therapists, and parents need to work together to ensure the child's hearing technology is fit appropriately to maximize performance in the various communication settings the child encounters. However, although interprofessional collaboration is a key concept in communication sciences and disorders, there is often a disconnect between what is regarded as best professional practice and the self-work needed to put true collaboration into practice. This paper offers practical tools, processes, and suggestions for service providers related to the self-awareness that is often required (yet seldom acknowledged) to create interprofessional teams with the dispositions and behaviors that enhance patient/client care.


2006 ◽  
Vol 40 (3) ◽  
pp. 39
Author(s):  
SHARON WORCESTER

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