scholarly journals Understanding the Psychological, Physiological, and Genetic Factors Affecting Precision Pain Medicine: A Narrative Review

2021 ◽  
Vol Volume 14 ◽  
pp. 3145-3161
Author(s):  
Andrea Chadwick ◽  
Andrew Frazier ◽  
Talal W Khan ◽  
Erin Young
Keyword(s):  
Genetic Factors ◽  
Narrative Review ◽  
Pain Medicine ◽  
Factors Affecting

scholarly journals Genetic predictors of participation in optional components of UK Biobank

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Jessica Tyrrell ◽  
Jie Zheng ◽  
Robin Beaumont ◽  
Kathryn Hinton ◽  
Tom G. Richardson ◽  
...  
Keyword(s):  
Sensitivity Analysis ◽  
Genetic Variants ◽  
Genetic Factors ◽  
Mendelian Randomization ◽  
Genetic Correlations ◽  
Mr Studies ◽  
Uk Biobank ◽  
Factors Affecting ◽  
Participation Bias ◽  
Genetic Predictors

AbstractLarge studies such as UK Biobank are increasingly used for GWAS and Mendelian randomization (MR) studies. However, selection into and dropout from studies may bias genetic and phenotypic associations. We examine genetic factors affecting participation in four optional components in up to 451,306 UK Biobank participants. We used GWAS to identify genetic variants associated with participation, MR to estimate effects of phenotypes on participation, and genetic correlations to compare participation bias across different studies. 32 variants were associated with participation in one of the optional components (P < 6 × 10−9), including loci with links to intelligence and Alzheimer’s disease. Genetic correlations demonstrated that participation bias was common across studies. MR showed that longer educational duration, older menarche and taller stature increased participation, whilst higher levels of adiposity, dyslipidaemia, neuroticism, Alzheimer’s and schizophrenia reduced participation. Our effect estimates can be used for sensitivity analysis to account for selective participation biases in genetic or non-genetic analyses.

Genetic factors affecting intelligence: Symposium

1954 ◽  
Vol 1 (1) ◽  
pp. 44-52 ◽  
Author(s):  
S. C. Reed ◽  
W. Reed ◽  
J. D. Palm
Keyword(s):  
Genetic Factors ◽  
Factors Affecting

The Nature and Origin of Common Phobic Fears

1979 ◽  
Vol 134 (4) ◽  
pp. 343-351 ◽  
Author(s):  
Svenn Torgersen
Keyword(s):  
Environmental Factors ◽  
Social Adjustment ◽  
Twin Study ◽  
Genetic Factors ◽  
Factor Analyses ◽  
Factors Affecting ◽  
Five Factors

SummaryBy means of a twin study an attempt was made to throw light upon the aetiology and nosology of phobic fears. Factor analyses revealed five factors, namely separation fears, animal fears, mutilation fears, social fears and nature fears. The study demonstrated that, apart from separation fears, genetic factors play a part in the strength as well as content of phobic fears. Environmental factors, affecting the development of dependence, reserve and neurotic traits generally, seemed also to be of some importance. It was further demonstrated that phobic fears were related to emotional and social adjustment and this was true to an even greater extent for separation fears.

scholarly journals Environmental and genetic factors affecting the weaning-estrus interval in sows

2011 ◽  
Vol 10 (4) ◽  
pp. 2692-2701 ◽  
Author(s):  
C.D.S. Leite ◽  
J.F. Lui ◽  
L.G. Albuquerque ◽  
D.N.M. Alves
Keyword(s):  
Genetic Factors ◽  
Factors Affecting

scholarly journals Predictors of Blood Pressure in Iranian Women- A Narrative Review

2020 ◽  
Author(s):  
Maryam Etaat ◽  
Zohre Tabatabaye ◽  
Samaneh Motamed Jahromi ◽  
Poneh Yosefi ◽  
Sadegh Sedigh ◽  
...  
Keyword(s):  
Blood Pressure ◽  
High Stress ◽  
Narrative Review ◽  
Iranian Women ◽  
Related Factors ◽  
Factors Affecting ◽  
Waist Size ◽  
Age Related ◽  
Diet And Exercise ◽  
Important Health

Introduction: hypertension is one of the most important health problems in the world and in developing countries, including Iran. The prevalence of hypertension among Iranian women is higher than men. This study aimed to investigate the predictive causes of hypertension among Iranian women. This study was a narrative review that was conducted by searching related studies and resources in databases of Google Scholar, SID, Pubmed, Magiran, Web of Science, and Scopus. Finally, 49 qualified articles were analyzed and the texts were reviewed. Based on the obtained data, the predictors of hypertension among Iranian women included the underlying factors of obesity (diet and exercise), psychosocial factors (stress, occupation and addiction) and age-related factors. Conclusion:  Obesity and increased waist size had a greater role in high blood pressure in Iranian women. After obesity, age and factors affecting them, lack of exercise, high stress, occupational factors, education, and addiction can also influence high blood pressure.As a result, it can be predicted that by identifying the risk factors, hypertension can be reduced among Iranian women; by teaching the causes and methods of preventing hypertension to the Iranian women as well as screening for timely diagnose and treatment, hypertension could be decreased among Iranian women.

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