scholarly journals Association between APE1 Asp148Glu polymorphism and the risk of urinary cancers: a meta-analysis of 18 case–control studies

2016 ◽  
pp. 1499
Author(s):  
Jue-Yu Zhou ◽  
Jie hui Zhong ◽  
Zheng Zhao ◽  
Jie Liu ◽  
Hai-Lang Yu ◽  
...  
Keyword(s):  



Tumor Biology ◽  
2014 ◽  
Vol 35 (5) ◽  
pp. 4727-4734 ◽  
Author(s):  
Zhiyong Zhao ◽  
Chuan Liu ◽  
Yong Zeng ◽  
Lei Gu ◽  
Mingzhen Ying ◽  
...  


Tumor Biology ◽  
2014 ◽  
Vol 35 (12) ◽  
pp. 12775-12776
Author(s):  
Fei Liu ◽  
Yong-Gang Wei ◽  
Wen-Tao Wang ◽  
Bo Li


Tumor Biology ◽  
2013 ◽  
Vol 35 (3) ◽  
pp. 2529-2535 ◽  
Author(s):  
Erdong Shen ◽  
Chuan Liu ◽  
Li Wei ◽  
Jianbing Hu ◽  
Jie Weng ◽  
...  


Tumor Biology ◽  
2013 ◽  
Vol 35 (4) ◽  
pp. 3597-3603 ◽  
Author(s):  
Wen Chen ◽  
Qin Wang ◽  
Mang Liu ◽  
Xiao-bing Ding


2010 ◽  
Vol 38 (7) ◽  
pp. 4537-4543 ◽  
Author(s):  
Ya-Nan Ji ◽  
Ping Zhan ◽  
Jing Wang ◽  
Li-Xin Qiu ◽  
Li-Ke Yu


2012 ◽  
Vol 40 (1) ◽  
pp. 171-176 ◽  
Author(s):  
Chuan Liu ◽  
Qinghua Yin ◽  
Lian Li ◽  
Ying-zhi Zhuang ◽  
Xuyu Zu ◽  
...  


2020 ◽  
Vol 43 (4) ◽  
pp. E24-34
Author(s):  
Caizhao Lin ◽  
Yuewei Jin ◽  
Shaobing Cheng ◽  
Weibing Wang

Background: Colorectal cancer (CRC) is recognized as one of the most common cancer globally. The association between CRC and apurinic endonuclease 1 (APE1) Asp148Glu polymorphism remains unclear; thus, this meta-analysis aimed to explore whether APE1 Asp148Glu polymorphism is related to CRC risk. Methods: Embase, PubMed, Cochrane library, CNKI and Wanfang databases were subject to a systematic search until April, 17, 2020 to evaluate the effect of APE1 Asp148Glu polymorphism on CRC risk. The associated strength was used to evaluate with odds ratios (ORs) with 95% confidence intervals (CIs) between Asp148Glu polymorphism and CRC risk. Subgroup analyses were also performed. Results: In total, 11 articles including 8,136 subjects (3,836 cases and 4,300 controls) were included. Five genetic models were analyzed, including the additive model (G vs. T), the heterozygote comparison (TG vs. TT), the homozygote comparison (GG vs. TT), the dominant model (TG+GG vs. TT), and the recessive model (GG vs. TG+TT). In these models, T refers to thymine and G refers to guanine. The APE1 Asp148Glu polymorphism in heterozygote comparison [OR (95%CI) = 1.36 (1.05, 1.75), P=0.019] and dominant model [OR (95%CI) =1.31 (1.07, 1.61), P=0.010] significantly increased CRC risk. No significant association was seen for the additive model [OR (95%CI) = 1.14 (1.00, 1.31), P=0.057], recessive model [OR (95%CI) = 0.97 (0.71, 1.31), P=0.826] or in homozygote comparison [OR (95%CI) = 1.15 (0.88, 1.52), P=0.309]. Moreover, CRC risk indicated a remarkable association with APE1 Asp148Glu polymorphism in the PCR-RFLP additive model, homozygote comparison and recessive model (PG) may be a potential risk factor for CRC.



2021 ◽  
Author(s):  
Yali Wei ◽  
Yan Meng ◽  
Na Li ◽  
Qian Wang ◽  
Liyong Chen

The purpose of the systematic review and meta-analysis was to determine if low-ratio n-6/n-3 long-chain polyunsaturated fatty acid (PUFA) supplementation affects serum inflammation markers based on current studies.



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