Population-Based Epidemiologic Study in Venous Diseases in Germany – Prevalence, Comorbidity, and Medical Needs in a Cohort of 19,104 Workers

We investigated the association between dietary micronutrient intakes and the risk of chronic kidney disease (CKD) in the Ansan-Ansung study of the Korean Genome and Epidemiologic Study (KoGES), a population-based prospective cohort study. Of 9079 cohort participants with a baseline estimate glomerular filtration rate (eGFR) ≥60 mL/min/1.73 m2 and a urine albumin to creatinine ratio (UACR) <300 mg/g and who were not diagnosed with CKD, we ascertained 1392 new CKD cases over 12 year follow-up periods. The risk of CKD according to dietary micronutrient intakes was presented using hazard ratios (HRs) and 95% confidence intervals (95% CIs) in a full multivariable Cox proportional hazard models, adjusted for multiple micronutrients and important clinico-epidemiological risk factors. Low dietary intakes of phosphorus (<400 mg/day), vitamin B2 (<0.7 mg/day) and high dietary intake of vitamin B6 (≥1.6 mg/day) and C (≥100 mg/day) were associated with an increased risk of CKD stage 3B and over, compared with the intake at recommended levels (HR = 6.78 [95%CI = 2.18–21.11]; HR = 2.90 [95%CI = 1.01–8.33]; HR = 2.71 [95%CI = 1.26–5.81]; HR = 1.83 [95%CI = 1.00–3.33], respectively). In the restricted population, excluding new CKD cases defined within 2 years, an additional association with low folate levels (<100 µg/day) in higher risk of CKD stage 3B and over was observed (HR = 6.72 [95%CI = 1.40–32.16]). None of the micronutrients showed a significant association with the risk of developing CKD stage 3A. Adequate intake of micronutrients may lower the risk of CKD stage 3B and over, suggesting that dietary guidelines are needed in the general population to prevent CKD.

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POPULATION-BASED EPIDEMIOLOGIC STUDY OF PSORIASIS WITH EMPHASIS ON QUALITY OF LIFE ASSESSMENT

Dermatologic Clinics ◽

10.1016/s0733-8635(05)70376-4 ◽

1996 ◽

Vol 14 (3) ◽

pp. 485-496 ◽

Cited By ~ 261

Author(s):

John Koo

Keyword(s):

Quality Of Life ◽

Epidemiologic Study ◽

Population Based ◽

Life Assessment ◽

Quality Of Life Assessment

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P211 MORTALITY IN INFLAMMATORY BOWEL DISEASE IN GIJÓN (ASTURIAS, SPAIN). A POPULATION-BASED EPIDEMIOLOGIC STUDY FROM 1954-2006

Journal of Crohn s and Colitis Supplements ◽

10.1016/s1873-9954(08)70222-2 ◽

2008 ◽

Vol 2 (1) ◽

pp. 67

Author(s):

C. Saro Gismera ◽

C. de la Coba ◽

M. Lacort Fernandez ◽

R. Garcia Lopez ◽

J. Perez Pariente ◽

...

Keyword(s):

Inflammatory Bowel Disease ◽

Bowel Disease ◽

Epidemiologic Study ◽

Population Based ◽

Inflammatory Bowel

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Epilepsy in Pakistan: Stigma and Psychosocial Problems. A Population-Based Epidemiologic Study

Epilepsia ◽

10.1111/j.1528-1157.1997.tb01195.x ◽

1997 ◽

Vol 38 (10) ◽

pp. 1069-1073 ◽

Cited By ~ 56

Author(s):

Hasan Aziz ◽

Syed Wasim Akhtar ◽

K. Zaki Hasan

Keyword(s):

Epidemiologic Study ◽

Psychosocial Problems ◽

Population Based

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Epidemiologic study of the C-3 epimer of 25-hydroxyvitamin D3 in a population-based sample

Clinical Nutrition ◽

10.1016/j.clnu.2013.06.005 ◽

2014 ◽

Vol 33 (3) ◽

pp. 421-425 ◽

Cited By ~ 23

Author(s):

Corinne D. Engelman ◽

Ronghai Bo ◽

Megan Zuelsdorff ◽

Hilary Steltenpohl ◽

Taylor Kirby ◽

...

Keyword(s):

Epidemiologic Study ◽

Population Based

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Comparison of adenocarcinoma (ACA) and squamous cell carcinoma (SCC) of the uterine cervix: A population-based epidemiologic study of 60,000 women in Brazil.

Journal of Clinical Oncology ◽

10.1200/jco.2013.31.15_suppl.1587 ◽

2013 ◽

Vol 31 (15_suppl) ◽

pp. 1587-1587

Author(s):

Angelica Noguelra Rodrigues ◽

Luiz Claudio Santos Thuler ◽

Anke Bergmann ◽

Suzana Sales de Aguiar ◽

Carlos Gil Moreira Ferreira

Keyword(s):

Uterine Cervix ◽

Epidemiologic Study ◽

Tumor Stage ◽

Population Based ◽

Response To Treatment ◽

Inadequate Response ◽

Chi Square ◽

Cervical Cancers ◽

Increased Risk ◽

Screening Strategies

1587 Background: Most cancers of the uterine cervix are SCC, but the relative and absolute incidence of ACA has risen in recent years, particularly in younger patients, and ACA now accounts for about 20% of invasive cervical cancers in screened populations worldwide. However, the developing world, with sub-optimally screened women, accounts for more than 80% of incident cervical cancers. Our objective was to compare epidemiological, clinical characteristics, and treatment outcome of ACA with those of SCC of the cervix, with respect to ethnic group, age and stage at diagnosis, and pattern of response to first treatment in a sub-optimally screened population. Methods: Data of cervical cancer patients with SCC and ACA (adenosquamous + adenocarcinoma) treated from 2000 through 2009 were obtained from the Brazilian Hospital Cancer Register databases. Summary odds ratios and chi-square tests were estimated. Results: A total of 60,883 patients were analyzed: 54,425 (89.4%) cases of SCC, and 6,458 (10.6%) of ACA. Compared to ACA, the SCC cohort were younger (49.37 x 51.83 years, p<0.001), more frequently black (58.1% x 49.2%, p<0.001), presented higher degree of illiteracy (22.7 x 16.1%, p<0.001), and alcohol (13 x 9.8%, p<0.001) and tobacco dependence (41.5 x 31%, p<0.001). Tumor stage at the time of diagnosis was also significantly different (p<0.01). Considering prognostic factors, in both subtypes, more than 60% of the patients were stage II or inferior and ACA was associated with a significantly increased risk of inadequate response after the first course of treatment (crude OR=1.14 CI95%=1.07-1.21; adjusted OR=0.94 CI95%=0.87-1.01) and of death (crude OR=1.26 CI95%=1.15-1.38; adjusted OR=1.1 CI95%=1.00-1.23). Conclusions: Differences between ACA and SCC were found in age at diagnosis, extent of disease and ethnic distribution. In spite of these differences, the inadequate response to treatment seems to be mainly the result of more advanced stage, rather than cell type. Screening strategies with higher sensitivity are necessary, and irrespectively of histological subtype, quality of treatment must be improved in developing countries.

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Epidemiologic study of risk factors for meningioma in the Mayo Clinic Study of Aging.

Journal of Clinical Oncology ◽

10.1200/jco.2017.35.15_suppl.2067 ◽

2017 ◽

Vol 35 (15_suppl) ◽

pp. 2067-2067

Author(s):

Alissa Butts ◽

Jeremy A. Syrjanen ◽

Jeremiah Aakre ◽

Paul D. Brown ◽

Clifford R. Jack ◽

...

Keyword(s):

Risk Factors ◽

Mayo Clinic ◽

Large Population ◽

Epidemiologic Study ◽

Significant Risk ◽

Female Gender ◽

Population Based ◽

Continuous Variable ◽

Health Study ◽

Clinic Study

2067 Background: An estimated 2% of the general population has a meningioma (Vernooij et al. 2007), which accounts for about 36% of all primary intracranial tumors (Ostrom et al. 2015). The most established risk factors are older age and female gender. One small study identified gender but no other risk factors with meningioma (Krampla et al 2004). A larger study using the Iowa Women’s Health study data found lower levels of physical activity, greater body mass index (BMI), greater height and uterine fibroids were associated with meningioma (Johnson et al. 2011). We sought to replicate these findings and to identify additional risk factors related to meningioma in a large population-based sample. Methods: Study participants were enrolled in the Mayo Clinic Study of Aging (MCSA), a population-based sample of Olmsted County, Minnesota residents used to study prevalence, incidence, and risk-factors for Mild Cognitive Impairment and dementia and includes a variety of medical factors. Using a text search of radiologists’ notes of 2,402 MCSA individuals, mean age 77±8 years and scanned between 2004-2014.We identified 52 subjects who had at least one meningioma. We estimated the association of selected potential risk factors with presence of meningioma using odds ratios and 95% confidence intervals from logistic regression models adjusted for age and gender, which informed the multivariable models. Results: In the initial models, significant risk factors identified included BMI (as a continuous variable) (OR = 1.06 95%CI 1.01 to 1.12), taking NSAIDS (OR = 2.11, 95%CI 1.13 to 3.95), aspirin (OR = 1.90, 95%CI 1.04 to 3.46), and blood pressure lowering medication (OR = 2.06, 95%CI 1.07 to 3.99). Protective factors included male gender (OR = 0.51, 95%CI 0.29 to 0.90), coronary artery disease (CAD; OR = 0.46, 95%CI 0.22 to 0.97) and higher Beck Anxiety Inventory (BAI) total score (OR = 0.88, 95%CI 0.78 to 0.98). Simultaneous adjustment for these factors in a multivariable model did not attenuate these associations. Conclusions: Findings reveal gender and BMI as risk factors for meningioma. Additionally, certain medications such as NSAIDS and BP lowering medications warrant follow up as potential factors related to development of meningioma.

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