scholarly journals TEN-YEAR FOLLOW-UP OF PRELIMINARY BICEPS BRACHIAL MUSCLE CONTRACTION IN THE REHABILITATION AND PROPHYLAXIS OF RECURRENT SHOULDER PAIN DUE TO TENDON DEGENERATION

2021 ◽  
Vol 9 (03) ◽  
pp. 792-802
Author(s):  
A. Aleksiev ◽  
◽  
V. Matsanova-Simova ◽  
S. Nikolova-Shopova ◽  
V. Dimitrova ◽  
...  

Introduction:- One of the overlooked facilitating factors of recurrent shoulder pain due to tendon degeneration is the periarticular muscle latency (M1, M2, and M3). It leads to a lack of muscle protection against the external loads on the shoulder during the initiation of every shoulder movement. This creates multiple repetitive micro-traumas, gradually accumulating to tendon degeneration. The only way to overtake the periarticular muscle latency and its consequences is the preliminary biceps brachial muscle contraction. Aim:- To study the effect of the preliminary biceps brachial muscle contraction on the short-term rehabilitation and the long-term prophylaxis of recurrent shoulder pain due to tendon degeneration. Material and Methods:- For 10 years were followed 44 outpatients (age 50.1 ± 14.8 years) with recurrent shoulder pain due to tendon degeneration. They were randomized into two groups – standard (n=22) and maneuver (n=22). Both groups received prophylactic recommendations and were treated for two weeks with exercise, interferential current, and laser. The maneuver group received an additional recommendation to perform preliminary biceps brachial muscle contraction before every movement of the shoulder during the daily activities. Pain intensity, shoulder mobility, periarticular muscle strength, number of recurrences, number of rehabilitation courses, and success rate of the maneuver were followed-up for two weeks and ten consecutive years. For the statistical analysis, ANOVA with Bonferronis tests and Pearsons correlation with regression tests were used. Results:- The pain decreased significantly after the first day in the maneuver group (P<0.05), and after the fifth day in the standard group (P<0.05). All results improved significantly after two weeks (P<0.05) and after one year (P<0.05) in both groups. The maneuver group showed superior results versus the standard group after two weeks (P<0.05) and after 10 consecutive years (P<0.05). With increasing the maneuver success rate, the short-term treatment effect and the long-term prophylactic effect increased in the maneuver group (P<0.05). There were no dropouts, side effects, or complications. Conclusion:- The preliminary biceps muscle contraction is appropriate an important additional recommendation in short-term treatment and long-term prophylaxis of recurrent shoulder pain due to tendon degeneration. It is simple, quick, effective, and without side effects or complications. It requires no allocation of space, time, or resources. This maneuver protects the shoulder before the initial external forces, avoiding the repetitive micro-traumas during the muscle latency, which is otherwise inevitable in daily activities. Another protecting factor is the increased muscle strength and co-contraction of all periarticular muscles, as a result of this bracing maneuver, leading to lesser pain with higher shoulder stability and mobility.

CNS Spectrums ◽  
1998 ◽  
Vol 3 (9) ◽  
pp. 64-71 ◽  
Author(s):  
Gary A. Christenson ◽  
Scott J. Crow ◽  
James E. Mitchell ◽  
Thomas B. Mackenzie ◽  
Ross D. Crosby ◽  
...  

AbstractThis short-term, open-label study investigates short- and long-term effects of the selective serotonin reuptake inhibitor (SSRI) fluvoxamine for the treatment of trichotillomania (TTM). Additionally, this study aimed to test the hypothesis that the presence of hair pulling compulsiveness is predictive of SSRI response. Nineteen subjects meeting the Diagnostic and Statistical Manual of Mental Disorders, Third Edition Revised, (DSM-III-R) criteria for TTM were treated with fluvoxamine at doses up to 300 mg/day. Random regression analysis of change across time for patients who completed the study (n=14) and those who dropped out (n=5) revealed statistically significant improvements in Physician Rating Scale, hair-pulling episodes, Trichotillomania Impairment Scale, and Trichotillomania Symptom Severity Scale, but not in estimated amount of hair pulled. In addition, the percentage of patients' focused or compulsive hair-pulling symptoms was predictive of treatment response. Unfortunately, all three subjects who entered long-term treatment displayed substantial movement back toward baseline by the end of 6 months. We concluded that fluvoxamine produces moderate reductions in symptoms during the short-term treatment of TTM and that the presence of focused or compulsive hair pulling may be predictive of treatment response. However, responses may be short lived when treatment is extended.


2020 ◽  
Vol 15 (2) ◽  
pp. 110-124
Author(s):  
Joy E. Ikekpeazu ◽  
Oliver C. Orji ◽  
Ikenna K. Uchendu ◽  
Lawrence U.S. Ezeanyika

Background and Objective: There may be a possible link between the use of HAART and oxidative stress-related mitochondrial dysfunction in HIV patients. We evaluated the mitochondrial and oxidative impacts of short and long-term administration of HAART on HIV patients attending the Enugu State University Teaching (ESUT) Hospital, Enugu, Nigeria following short and long-term therapy. Methods: 96 patients categorized into four groups of 24 individuals were recruited for the study. Group 1 comprised of age-matched, apparently healthy, sero-negative individuals (the No HIV group); group 2 consisted of HIV sero-positive individuals who had not started any form of treatment (the Treatment naïve group). Individuals in group 3 were known HIV patients on HAART for less than one year (Short-term treatment group), while group 4 comprised of HIV patients on HAART for more than one year (Long-term treatment group). All patients were aged between 18 to 60 years and attended the HIV clinic at the time of the study. Determination of total antioxidant status (TAS in nmol/l), malondialdehyde (MDA in mmol/l), CD4+ count in cells/μl, and genomic studies were all done using standard operative procedures. Results: We found that the long-term treatment group had significantly raised the levels of MDA, as well as significantly diminished TAS compared to the Short-term treatment and No HIV groups (P<0.05). In addition, there was significantly elevated variation in the copy number of mitochondrial genes (mtDNA: D-loop, ATPase 8, TRNALEU uur) in the long-term treatment group. Interpretation and Conclusion: Long-term treatment with HAART increases oxidative stress and causes mitochondrial alterations in HIV patients.


2017 ◽  
Vol 22 (6) ◽  
pp. 518-524 ◽  
Author(s):  
Marco P Donadini ◽  
Francesco Dentali ◽  
Samuela Pegoraro ◽  
Fulvio Pomero ◽  
Chiara Brignone ◽  
...  

Isolated distal deep vein thrombosis (IDDVT) is a common clinical manifestation of venous thromboembolism (VTE). However, there are only scant and heterogeneous data available on the long-term risk of recurrent VTE after IDDVT, and the optimal therapeutic management remains uncertain. We carried out a retrospective cohort study of consecutive patients diagnosed with symptomatic IDDVT between 2004 and 2011, according to a predefined short-term treatment protocol (low molecular weight heparin (LMWH) for 4–6 weeks). The primary outcome was the occurrence of recurrent VTE. A total of 321 patients were enrolled. IDDVT was associated with a transient risk factor or cancer in 165 (51.4%) and 56 (17.4%) patients, respectively. LMWH was administered for 4–6 weeks to 280 patients (87.2%), who were included in the primary analysis. Overall, during a mean follow-up of 42.3 months, 42 patients (15%) developed recurrent VTE, which occurred as proximal DVT or PE in 21 cases. The recurrence rate of VTE per 100 patient-years was 3.5 in patients with transient risk factors, 7.2 in patients with unprovoked IDDVT, and 5.9 in patients with cancer ( p=0.018). At multivariable analysis, unprovoked IDDVT and previous VTE were significantly associated with recurrent VTE (HR 2.16, 95% CI 1.12–4.16 and HR 1.97, 95% CI 1.01–3.86, respectively). In conclusion, the long-term risk of recurrent VTE after IDDVT treated for 4–6 weeks is not negligible, in particular in patients with unprovoked IDDVT or cancer. Further studies are needed to clarify whether a longer, but definite treatment duration effectively prevents these recurrences.


Heart ◽  
1992 ◽  
Vol 67 (6) ◽  
pp. 491-497 ◽  
Author(s):  
M Zehender ◽  
S Hohnloser ◽  
A Geibel ◽  
A Furtwangler ◽  
M Olschewski ◽  
...  

1994 ◽  
Vol 180 (2) ◽  
pp. 231-234 ◽  
Author(s):  
Cordian Beyer ◽  
Walter Kolbinger ◽  
Ingrid Reisert ◽  
Christof Pilgrim

Sign in / Sign up

Export Citation Format

Share Document