The Effects of Nonsurgical Periodontal Therapy on Serum Levels of Procalcitonin in Patients with Chronic and Aggressive Periodontitis

Introduction: Chronic periodontitis is a multifactorial disease resulting in the inflammation and destruction of the supporting structures. Early detection of periodontal changes, prognosis and efficacy of treatment have been monitored by Alkaline Phosphatase Levels (ALP) levels. Objective: This study was carried out to determine level of ALP in saliva and serum before and after periodontal therapy. Methods: This pretest posttest study included 22 patients with generalised chronic periodontitis (GCP). The patients received nonsurgical periodontal therapy (NSPT). Saliva and serum levels of ALP were measured at baseline and after two months of periodontal therapy. Results: Twenty-two patients of mean age 44 years were analysed. Participants had significantly better periodontal parameters after two months. Salivary ALP levels, which were high at baseline, decreased after periodontal treatment. A significant positive correlation (0.0001) was found between the salivary levels of ALP and periodontal inflammatory conditions. Gingival index was found directly proportional with salivary ALP level but not with serum ALP. Conclusion: Periodontal therapy lowered the levels of ALP saliva in GCP patients with high ALP levels. Biochemical analysis of enzymes found in saliva may help in patients’ evaluation to determine the control and progression of periodontal destruction and aid in a correct diagnosis, prognosis and, consequently, better treatment.

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Outcomes of nonsurgical periodontal therapy in severe generalized aggressive periodontitis

Journal of Periodontal & Implant Science ◽

10.5051/jpis.2014.44.4.201 ◽

2014 ◽

Vol 44 (4) ◽

pp. 201

Author(s):

Amal Bouziane ◽

Latifa Benrachadi ◽

Redouane Abouqal ◽

Oumkeltoum Ennibi

Keyword(s):

Aggressive Periodontitis ◽

Periodontal Therapy ◽

Nonsurgical Periodontal Therapy

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09 / A Clinical and Microbiological Comparison of Er:YAG Laser and Mechanical Debridement For The Nonsurgical Periodontal Therapy: A Randomized Controlled Clinical Study

10.26226/morressier.5ac383212afeeb00097a4538 ◽

2018 ◽

Author(s):

Tuğba Zengin Çelik

Keyword(s):

Clinical Study ◽

Er:Yag Laser ◽

Periodontal Therapy ◽

Randomized Controlled ◽

Nonsurgical Periodontal Therapy ◽

Controlled Clinical Study

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Effect of nonsurgical periodontal therapy with additional photodynamic therapy on the level of MMP-9 and TIMP-1 in GCF in chronic periodontitis patients.

10.26226/morressier.5ac3831d2afeeb00097a3f0a ◽

2018 ◽

Author(s):

Ewa Dolińska

Keyword(s):

Photodynamic Therapy ◽

Chronic Periodontitis ◽

Periodontal Therapy ◽

Nonsurgical Periodontal Therapy

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Antibiotic Use in Periodontal Therapy among French Dentists and Factors Which Influence Prescribing Practices

Antibiotics ◽

10.3390/antibiotics10030303 ◽

2021 ◽

Vol 10 (3) ◽

pp. 303

Author(s):

Kevimy Agossa ◽

Kadiatou Sy ◽

Théo Mainville ◽

Marjolaine Gosset ◽

Sylvie Jeanne ◽

...

Keyword(s):

Antibiotic Use ◽

Aggressive Periodontitis ◽

Periodontal Therapy ◽

Research Network ◽

Prescribing Practices ◽

French Society ◽

Private Practitioners ◽

First Line Therapy ◽

Practice Based Research ◽

Systemic Antibiotics

The aim of the present survey is to investigate the use of antibiotics during periodontal therapy among French dentists with a focus on exploring potential differences between various groups of practitioners. A self-administered questionnaire was distributed to different groups of practitioners including members of (i) the French Society of Periodontology and Implantology; (ii) the College of University Teachers in Periodontology and, (iii) private practitioners participating in the French general dental practice-based research network. 272 questionnaires were included in the analysis. Prescription patterns were globally in line with the current recommendations. Systemic antibiotics are most frequently used as a first-line therapy in necrotizing periodontitis (92%) and aggressive periodontitis (53.3% to 66.1%). However, malpractice still exists, including in the management of periodontal abscesses. Antibiotics are prescribed (i) less frequently for periodontal abscesses and (ii) more frequently for generalized aggressive periodontitis by members of the periodontal society and University college (p < 0.05). Amoxicillin (59.9%) and the amoxicillin + metronidazole (59.6%) combination were the most frequently prescribed molecules. Providing a high number of periodontal treatments per week, being more recently graduated, having a post-graduate certificate in periodontology and holding or having held an academic position/hospital practice were all factors associated with a better knowledge of and/or more adequate antibiotic use.

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Adjunctive air-polishing with erythritol in nonsurgical periodontal therapy: a randomized clinical trial

BMC Oral Health ◽

10.1186/s12903-020-01363-5 ◽

2020 ◽

Vol 20 (1) ◽

Author(s):

Holger F. R. Jentsch ◽

Christian Flechsig ◽

Benjamin Kette ◽

Sigrun Eick

Keyword(s):

Test Group ◽

Nonparametric Tests ◽

Periodontal Therapy ◽

Periodontal Pocket ◽

Control Group ◽

Clinical Variables ◽

Air Polishing ◽

Probing Depth ◽

Nonsurgical Periodontal Therapy ◽

Attachment Level

Abstract Background This study was aimed to investigate if the adjunctive use of erythritol air-polishing powder applied with the nozzle-system during subgingival instrumentation (SI) has an effect on the outcome of non-surgical periodontal treatment in patients with moderate to severe periodontitis. Methods Fourty-two individuals with periodontitis received nonsurgical periodontal therapy by SI without (controls, n = 21) and with adjunctive air-polishing using nozzle + erythritol powder (test, n = 21). They were analyzed for the clinical variables BOP (primary outcome at six months), probing depth (PD), attachment level, four selected microorganisms and two biomarkers at baseline, before SI as well as three and six months after SI. Statistical analysis included nonparametric tests for intra- and intergroup comparisons. Results In both groups, the clinical variables PD, attachment level and BOP significantly improved three and six months after SI. The number of sites with PD ≥ 5 mm was significantly lower in the test group than in the control group after six months. At six months versus baseline, there were significant reductions of Tannerella forsythia and Treponema denticola counts as well as lower levels of MMP-8 in the test group. Conclusions Subgingival instrumentation with adjunctive erythritol air-polishing powder does not reduce BOP. But it may add beneficial effects like reducing the probing depth measured as number of residual periodontal pocket with PD ≥ 5 mm when compared with subgingival instrumentation only. Clinical relevance The adjunctive use of erythritol air-polishing powder applied with the nozzle-system during SI may improve the clinical outcome of SI and may reduce the need for periodontal surgery. Trial registration The study was retrospectively registered in the German register of clinical trials, DRKS00015239 on 6th August 2018, https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL.

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