Effect of nonsurgical periodontal therapy with additional photodynamic therapy on the level of MMP-9 and TIMP-1 in GCF in chronic periodontitis patients.

2018 ◽  
Author(s):  
Ewa Dolińska
Keyword(s):  
Photodynamic Therapy ◽  
Chronic Periodontitis ◽  
Periodontal Therapy ◽  
Nonsurgical Periodontal Therapy

scholarly journals Evaluation of efficacy of photodynamic therapy as an adjunct to nonsurgical periodontal therapy in treatment of chronic periodontitis patients: A clinico-microbiological study

2016 ◽  
Vol 27 (5) ◽  
pp. 483 ◽  
Author(s):  
KRavi Raj ◽  
SVVS Musalaiah ◽  
M Nagasri ◽  
PAravind Kumar ◽  
PIndeevar Reddy ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Chronic Periodontitis ◽  
Periodontal Therapy ◽  
Microbiological Study ◽  
Nonsurgical Periodontal Therapy

scholarly journals The Effect of Nonsurgical Periodontal Therapy on HNP1-3 Level in Gingival Crevicular Fluid of Chronic Periodontitis Patients

2017 ◽  
Vol 65 (4) ◽  
pp. 355-361 ◽  
Author(s):  
Ewa Dolińska ◽  
Anna Skurska ◽  
Małgorzata Pietruska ◽  
Violetta Dymicka-Piekarska ◽  
Robert Milewski ◽  
...  
Keyword(s):  
Chronic Periodontitis ◽  
Gingival Crevicular Fluid ◽  
Periodontal Therapy ◽  
Nonsurgical Periodontal Therapy ◽  
Crevicular Fluid

scholarly journals Effect of nonsurgical periodontal therapy on serum levels of interleukin-1β and interleukin-8 in smokers and nonsmokers with chronic periodontitis

2020 ◽  
Vol 12 (5) ◽  
pp. 313
Author(s):  
Steffi Vijayakumar ◽  
Elizabeth Koshi ◽  
Arun Sadasivan ◽  
RS Indhuja ◽  
ChitraG Vallabhan
Keyword(s):  
Chronic Periodontitis ◽  
Serum Levels ◽  
Periodontal Therapy ◽  
Interleukin 8 ◽  
Interleukin 1Β ◽  
Nonsurgical Periodontal Therapy

scholarly journals Effect of Nonsurgical Periodontal Therapy on Crevicular Fluid and Serum Glutathione Peroxidase Levels

2012 ◽  
Vol 32 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Swati Pradeep Patel ◽  
Nishanth S. Rao ◽  
A. R. Pradeep
Keyword(s):  
Oxidative Stress ◽  
Glutathione Peroxidase ◽  
Periodontal Disease ◽  
Chronic Periodontitis ◽  
Periodontal Diseases ◽  
Periodontal Therapy ◽  
Enzyme Linked Immunosorbent Assay ◽  
Pocket Depth ◽  
Nonsurgical Periodontal Therapy ◽  
Crevicular Fluid

Background: Plasma glutathione peroxidase (eGPx) is an important selenium containing antioxidant in human defense against oxidative stress. While crevicular fluid (GCF) eGPx levels and its association with periodontal disease is well documented, there is no data on correlation of GCF and serum eGPx levels in chronic periodontitis. Hence this study was undertaken to further probe into the role of oxidative stress in periodontal diseases and effect of nonsurgical periodontal therapy (NSPT) by correlating GCF and serum levels of eGPx.Materials and methods: Thirty subjects (16-Males and 14-Females; age: 30–38 years) participated in the study. The subjects were divided, based on gingival index, probing pocket depth and clinical attachment level into: Healthy (group-1,n=10), Gingivitis (group-2,n=10) and Periodontitis (group-3,n=10). Chronic periodontitis patients after NSPT constituted group 4. GCF and serum samples collected from each subject were quantified for eGPx levels using Enzyme linked Immunosorbent Assay.Results: The mean eGPx concentrations increased from health (14.01 ng/μl and 78.26 ng/ml) to gingivitis (22.86 ng/μl and 90.44 ng/ml) and then to periodontitis (29.89 ng/μl and 103.43 ng/ml), in GCF and serum respectively. After NSPT, there was statistically significant reduction in eGPx concentration in GCF and serum (19.41 ng/μl and 85.21 ng/ml). Further, all the GCF eGPx values showed a positive correlation to that of serum eGPx level.Conclusion: Thus, increased eGPx concentration in GCF can be considered as an indicator of local increase in oxidative stress. While, increase in serum eGPx levels indicates that periodontal disease can also lead to increased oxidative stress at the systemic level.

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