scholarly journals The capability of chest computed tomography in the diagnosis of bronchopulmonary dysplasia outcomes in premature infants

2019 ◽  
pp. 28-32
Author(s):  
E. B. Pavlinova ◽  
I. A. Kirshina ◽  
G. A. Sakhipova ◽  
A. Yu. Gorlina ◽  
O. A. Savchenko ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Lung Tissue ◽  
Structural Changes ◽  
Late Childhood ◽  
Radiological Findings ◽  
Chest Computed Tomography ◽  
Infant Respiratory Distress Syndrome

Purpose of the study was to establish clinical and radiological features of bronchopulmonary dysplasia (BPD) outcomes in children. Materials and methods. A prospective follow-up study of 132 premature infants with infant respiratory distress syndrome (IRDS) was analyzed. BPD was developed in 66 cases. At a late childhood, clinical and radiological outcomes of the transferred conditions were diagnosed on the basis of anamnesis, clinical examination, and results of chest computed tomography (CT). Results. Clinical recovery was observed significantly more frequently in the outcome of IRDS without BPD development (69.6% versus 31.8% in the case of BPD development). In patients with BPD in the anamnesis, the odds ratio of asthma developed in the late childhood was 5.304 times higher than in children who had IRDS. The majority (62 cases, 93.9%) of children who had IRDS did not have structural changes in lung tissue according to CT (p = 0.000), 21 (31.8%) children with BPD had abnormal CT. In BPD, typical radiological findings were hypoattenuated lung areas (p = 0.020) and areas of pulmonary fibrosis (p = 0.016). Conclusion. Chest CT could be assigned to the patients with BPD in the anamnesis to assess lung tissue structural changes and diagnose outcomes of the disease.

scholarly journals Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma: A Report of 2 Cases and Literature Review

2021 ◽  
Vol 1 (1) ◽  
pp. 36-40
Author(s):  
Xiangting Xie ◽  
◽  
Ying Zhang ◽  
Xiaoyan Tan ◽  
Yun Luo ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Malt Lymphoma ◽  
Lymphoid Tissue ◽  
Relevant Literature ◽  
Complete Resection ◽  
The Other ◽  
Malignant Lymphomas ◽  
Chest Computed Tomography ◽  
Pulmonary Malt Lymphoma

Pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is indolent and progresses more slowly than other malignant lymphomas. The clinical features are not specific and the diagnosis can often be difficult. Here, we present two rare cases of pulmonary MALT lymphoma. Both patients were incidentally found lesions in the lungs with chest computed tomography during physical examination. They were finally diagnosed by pathological biopsy. One received complete resection, the other was treated with chemotherapy. There were no recurrence in the two patients during follow-up. We also review relevant literature to provide a better recognition of this disease.

scholarly journals Chest Computed Tomography and Clinical Follow-Up of Discharged Patients with COVID-19 in Wenzhou City, Zhejiang, China

2020 ◽  
Vol 17 (10) ◽  
pp. 1231-1237 ◽  
Author(s):  
Chenbin Liu ◽  
Ling Ye ◽  
Ruike Xia ◽  
Xudong Zheng ◽  
Cuiyun Yuan ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Chest Computed Tomography ◽  
Discharged Patients

Not just another large atrial septal defect: complex anatomy, challenging procedure, and an unusual complication

2020 ◽  
Vol 30 (7) ◽  
pp. 1052-1056
Author(s):  
Raymond N. Haddad ◽  
Tony Abdel Massih ◽  
Zakhia Saliba
Keyword(s):  
Computed Tomography ◽  
Pericardial Effusion ◽  
Atrial Septal Defect ◽  
Septal Defect ◽  
Clinical Findings ◽  
Clinical Judgement ◽  
Unusual Complication ◽  
Chest Computed Tomography ◽  
Complex Anatomy

AbstractWe report the case of a 59-year-old patient with a complex atrial septal defect in whom a 40-mm Amplatzer™ septal occluder was surgically extracted 50 days following implantation. Deployment manoeuvres were challenging leading to an immediate pericardial effusion that was closely monitored and uneventfully drained after 11 days. A dry pericardium was documented until 4 weeks of outpatient routine follow-up. However, the device was surgically explanted 2 weeks later, when an urgent chest computed tomography performed for worrisome symptoms showed pericardial effusion recurrence with peripheral contrast enhancement. Surprisingly, the surgical view showed a well-positioned device and an intact pericardium. We discuss the atypical sequence of clinical findings misleading our clinical judgement and precipitating surgery.

scholarly journals Spontaneous pneumothorax and subpleural bullae in a patient with COVID-19: a 92-day observation

2020 ◽  
Vol 58 (4) ◽  
pp. 858-860
Author(s):  
Qianqian Fan ◽  
Feng Pan ◽  
Lian Yang
Keyword(s):  
Computed Tomography ◽  
Spontaneous Pneumothorax ◽  
Sudden Increase ◽  
Alveolar Pressure ◽  
Chest Computed Tomography ◽  
Computed Tomography Images

Abstract This report describes a patient with COVID-19 who developed spontaneous pneumothorax and subpleural bullae during the course of the infection. Consecutive chest computed tomography images indicated that COVID-19-associated pneumonia had damaged the subpleural alveoli and distal bronchus. Coughing might have induced a sudden increase in intra-alveolar pressure, leading to the rupture of the subpleural alveoli and distal bronchus and resulting in spontaneous pneumothorax and subpleural bullae. At the 92-day follow-up, the pneumothorax and subpleural bullae had completely resolved, which indicated that these complications had self-limiting features.

scholarly journals Functionalized synchrotron in-line phase-contrast computed tomography: a novel approach for simultaneous quantification of structural alterations and localization of barium-labelled alveolar macrophages within mouse lung samples

2015 ◽  
Vol 22 (1) ◽  
pp. 143-155 ◽  
Author(s):  
Christian Dullin ◽  
Simeone dal Monego ◽  
Emanuel Larsson ◽  
Sara Mohammadi ◽  
Martin Krenkel ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Lung Tissue ◽  
Alveolar Macrophages ◽  
Phase Contrast ◽  
Phase Retrieval ◽  
Cell Tracking ◽  
Structural Changes ◽  
Mouse Lung ◽  
X Ray ◽  
Novel Approach

Functionalized computed tomography (CT) in combination with labelled cells is virtually non-existent due to the limited sensitivity of X-ray-absorption-based imaging, but would be highly desirable to realise cell tracking studies in entire organisms. In this study we applied in-line free propagation X-ray phase-contrast CT (XPCT) in an allergic asthma mouse model to assess structural changes as well as the biodistribution of barium-labelled macrophages in lung tissue. Alveolar macrophages that were barium-sulfate-loaded and fluorescent-labelled were instilled intratracheally into asthmatic and control mice. Mice were sacrificed after 24 h, lungs were keptin situ, inflated with air and scanned utilizing XPCT at the SYRMEP beamline (Elettra Synchrotron Light Source, Italy). Single-distance phase retrieval was used to generate data sets with ten times greater contrast-to-noise ratio than absorption-based CT (in our setup), thus allowing to depict and quantify structural hallmarks of asthmatic lungs such as reduced air volume, obstruction of airways and increased soft-tissue content. Furthermore, we found a higher concentration as well as a specific accumulation of the barium-labelled macrophages in asthmatic lung tissue. It is believe that XPCT will be beneficial in preclinical asthma research for both the assessment of therapeutic response as well as the analysis of the role of the recruitment of macrophages to inflammatory sites.

scholarly journals Inhaled nitric oxide (iNO) for preventing prematurity-related bronchopulmonary dysplasia (BPD): 7-year follow-up of the European Union Nitric Oxide (EUNO) trial

2021 ◽  
Vol 49 (1) ◽  
pp. 104-110
Author(s):  
Anne Greenough ◽  
Fabrice Decobert ◽  
David Field ◽  
Mikko Hallman ◽  
Helmut D. Hummler ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Bronchopulmonary Dysplasia ◽  
Premature Infants ◽  
Oxygen Therapy ◽  
Well Being ◽  
Inhaled Nitric Oxide ◽  
Current Evidence ◽  
Home Oxygen Therapy

AbstractObjectivesMost studies of inhaled nitric oxide (iNO) for prevention of bronchopulmonary dysplasia (BPD) in premature infants have focused on short-term mortality and morbidity. Our aim was to determine the long-term effects of iNO.MethodsA 7-year follow-up was undertaken of infants entered into a multicenter, double-blind, randomized, placebo-controlled trial of iNO for prevention of BPD in premature infants born between 24 and 28 weeks plus six days of gestation. At 7 years, survival and hospital admissions since the 2-year follow-up, home oxygen therapy in the past year, therapies used in the previous month and growth assessments were determined. Questionnaires were used to compare general health, well-being, and quality of life.ResultsA total of 305 children were assessed. No deaths were reported. Rates of hospitalization for respiratory problems (6.6 vs. 10.5%, iNO and placebo group, respectively) and use of respiratory medications (6.6 vs. 9.2%) were similar. Two patients who received iNO and one who received placebo had received home oxygen therapy. There were no significant differences in any questionnaire-documented health outcomes.ConclusionsiNO for prevention of BPD in very premature infants with respiratory distress did not result in long-term benefits or adverse long-term sequelae. In the light of current evidence, routine use of iNO cannot be recommended for prevention of BPD in preterm infants.

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