ASSESSMENT OF LV AND RV SYSTOLIC FUNCTIONS IN PATIENTS WITH CONNECTIVE TISSUE DISEASES BY 2D SPECKLE TRACKING ECHOCARDIOGRAPHY

Background and objectives: Childhood obesity has reached epidemic levels in the world. Obesity in children is defined as a body mass index (BMI) equal to or above the 95th percentile for age and sex. The aim of this study was to determine early changes in cardiac structure and function in obese children by comparing them with their nonobese peers, using echocardiography methods. Materials and methods: The study enrolled 35 obese and 37 age-matched nonobese children. Standardized 2-dimensional (2D), pulsed wave tissue Doppler, and 2D speckle tracking echocardiography were performed. The z-score BMI and lipid metabolism were assessed in all children. Results: Obese children (aged 13.51 ± 2.15 years; 20 boys; BMI z-score of 0.88 ± 0.63) were characterized by enlarged ventricular and atrial volumes, a thicker left ventricular posterior wall, and increased left ventricular mass. Decreased LV and RV systolic and diastolic function was found in obese children. Atrial peak negative (contraction) strain (−2.05% ± 2.17% vs. −4.87% ± 2.97%, p < 0.001), LV and RV global longitudinal strain (−13.3% ± 2.88% vs. −16.87% ± 3.39%; −12.51% ± 10.09% vs. −21.51% ± 7.42%, p < 0.001), and LV global circumferential strain (−17.0 ± 2.7% vs. −19.5 ± 2.9%, p < 0.001) were reduced in obese children. LV torsion (17.94° ± 2.07° vs. 12.45° ± 3.94°, p < 0.001) and normalized torsion (2.49 ± 0.4°/cm vs. 1.86 ± 0.61°/cm, p = 0.001) were greater in obese than nonobese children. A significant inverse correlation was found between LV and RV global longitudinal strain and BMI (r = −0.526, p < 0.01; r = −0.434, p < 0.01) and total cholesterol (r = −0.417, p < 0.01). Multivariate analysis revealed that the BMI z-score was independently related to LV and RV global longitudinal strain as well as LV circumferential and radial strain. Conclusion: 2D speckle tracking echocardiography is beneficial in the early detection of regional LV systolic and diastolic dysfunctions, with preserved ejection fraction as well as additional RV and atrial involvement, in obese children. Obesity may negatively influence atrial and ventricular function, as measured by 2D speckle tracking echocardiography. Obese children, though they are apparently healthy, may have subclinical myocardial dysfunction.

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Left ventricular 2D speckle tracking echocardiography for detection of systolic dysfunction in genetic, dilated cardiomyopathies

European Heart Journal - Cardiovascular Imaging ◽

10.1093/ehjci/jey169 ◽

2018 ◽

Vol 20 (6) ◽

pp. 694-699 ◽

Cited By ~ 8

Author(s):

Pieter van der Bijl ◽

Marianne Bootsma ◽

Yasmine L Hiemstra ◽

Nina Ajmone Marsan ◽

Jeroen J Bax ◽

...

Keyword(s):

Speckle Tracking ◽

Speckle Tracking Echocardiography ◽

Systolic Dysfunction ◽

Left Ventricular ◽

2D Speckle Tracking

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MECHANISMS OF LEFT VENTRICULAR THROMBUS FORMATION IN HEART FAILURE WITH REDUCED EJECTION FRACTION: NOVEL INSIGHTS FROM 2D SPECKLE-TRACKING ECHOCARDIOGRAPHY

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(18)31457-8 ◽

2018 ◽

Vol 71 (11) ◽

pp. A916

Author(s):

Dhruv Chawla ◽

Laura Johnson ◽

Tadele Mengesha ◽

Vinay Thohan

Keyword(s):

Heart Failure ◽

Ejection Fraction ◽

Speckle Tracking ◽

Speckle Tracking Echocardiography ◽

Thrombus Formation ◽

Left Ventricular ◽

Left Ventricular Thrombus ◽

Reduced Ejection Fraction ◽

Ventricular Thrombus ◽

2D Speckle Tracking

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Comparison of left ventricular systolic function by 2D speckle-tracking echocardiography between normal pregnant women and pregnant women with preeclampsia

Journal of Cardiovascular and Thoracic Research ◽

10.15171/jcvtr.2019.50 ◽

2019 ◽

Vol 11 (4) ◽

pp. 309-313

Author(s):

Atoosa Mostafavi ◽

Yaser Tase Zar ◽

Farahnaz Nikdoust ◽

Seyed Abdolhossein Tabatabaei

Keyword(s):

Pregnant Women ◽

Speckle Tracking ◽

Circumferential Strain ◽

Speckle Tracking Echocardiography ◽

Systolic Function ◽

Left Ventricular ◽

Ventricular Systolic Function ◽

2D Speckle Tracking ◽

The Mean ◽

The Right

Introduction: In light of previous studies reporting the significant effects of preeclampsia on cardiac dimensions, we sought to evaluate changes in the left ventricular (LV) systolic and diastolic functions in patients with preeclampsia with a view to investigating changes in cardiac strain. <br /> Methods: This cross-sectional study evaluated healthy pregnant women and pregnant women suffering from preeclampsia who were referred to our hospital for routine healthcare services. LV strain was measured by 2D speckle-tracking echocardiography. <br /> Results: Compared with the healthy group, echocardiography in the group with preeclampsia showed a significant increase in the LV end-diastolic diameter (47.43 ± 4.94 mm vs 44.84 ± 4.30 mm; P = 0.008), the LV end-systolic diameter (31.16 ± 33.3 mm vs 29.20 ± 3.75 mm; P = 0.008), and the right ventricular diameter (27.93 ± 1.71 mm vs 24.53 ± 23.3; P = 0.001). The mean global longitudinal strain was -18.69 ± 2.8 in the group with preeclampsia and -19.39 ± 3.49 in the healthy group, with the difference not constituting statistical significance (P = 0.164). The mean global circumferential strain in the groups with and without preeclampsia was -20.4 ± 12.4 and -22.68 ± 5.50, respectively, which was significantly lower in the preeclampsia group (P = 0.028).<br /> Conclusion: The development of preeclampsia was associated with an increase in the right and left ventricular diameters, as well as a decrease in the ventricular systolic function, demonstrated by a decline in global circumferential strain.

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