scholarly journals Cardiac Complications in Infants of Diabetic Mothers in NICU, A Cross Sectional Prospective Study

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Dina Ali ◽  
Amira Hamed ◽  
Mohammed Aladawy ◽  
Ahmed Ismail
Keyword(s):  
Prospective Study ◽  
Cardiac Complications ◽  
Cross Sectional ◽  
Infants Of Diabetic Mothers ◽  
Diabetic Mothers

scholarly journals Glycemic status of infants of diabetic mothers; a study at the Children’s Hospital and Institute of Child Health, Multan.

2021 ◽  
Vol 28 (11) ◽  
pp. 1626-1632
Author(s):  
Abdur Rehman ◽  
Waqas Imran Khan ◽  
Ahmad Iqbal Quddusi ◽  
Aashee Nadeem ◽  
Nazia Fatima ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Child Health ◽  
Cross Sectional Study ◽  
Large For Gestational Age ◽  
Cross Sectional ◽  
Infants Of Diabetic Mothers ◽  
Children's Hospital ◽  
Increased Risk ◽  
Children’S Hospital ◽  
Diabetic Mothers

Objective: To find out the frequency of hypoglycemia among infants of diabetic mothers (IDMs) and factors affecting it. Study Design: Descriptive Cross Sectional study. Setting: Department of Neonatology, The Children’s Hospital and Institute of Child Health, Multan, Pakistan. Period: September 2019 t0 June 2020. Material & Methods: A total of 186 IDMs admitted to department of neonatology during the study period were enrolled. Bed side blood glucose (BG) was measured using “Accu Chek Performa Blood Glucose Meter” at 0, 2, 4, 6, 8, 12, 18 and 24 hours of life. All IDMs (Infants of Diabetic Mothers) were labeled either gestational diabetes mellitus (GDM) or pre GDM (pre-GDM). IDMs noted to have hypoglycemia during 1st 24 hours of life were described as hypoglycemic and others were labeled as normoglycemic IDMs. Results: Hypoglycemia was noted among 77 (41.4%) IDMs. Duration of disease was significantly more among mothers of hypoglycemic infants (27.62+28.8months vs. 19.69+24.41 months, p=0.0444). Significantly more large for gestational age (LGA) IDMs were found to be hypoglycemic in comparison to normoglycaemic ones (32.5% vs. 16.5%, p=0.0110). Among a total of 77 IDMs noted to have hypoglycemia, 34 (44.1%) were born to mothers who had GDM while remaining 43 (55.9%) were born to pre-GDM mothers. Significantly more IDMs were preterm among pre-GDM mothers when compared to GDM mothers (53.5% vs. 23.5%, p=0.0077). Conclusion: Hypoglycemia is frequent problem among IDMs. Increased duration of diabetes among mothers, LGA as well as preterm IDMs are found to have significantly increased risk of developing hypoglycemia.

scholarly journals Cardiovascular malformations in infants of diabetic mothers: a retrospective study

2019 ◽  
Vol 6 (5) ◽  
pp. 1998
Author(s):  
Poornima Shankar ◽  
Jayalalitha S. Marol ◽  
Shilpa Deborah Lysander ◽  
Abhishek Manohar
Keyword(s):  
Maternal Diabetes ◽  
Cardiac Anomaly ◽  
Cardiac Complications ◽  
Retrospective Case ◽  
Infants Of Diabetic Mothers ◽  
Significant Difference ◽  
Cardiovascular Anomalies ◽  
Control Study ◽  
Diabetic Mothers

Background: Despite improvements in medical care provided during pregnancy to diabetic mothers, the cardiac complications in their infants are still more frequent than in infants of general population.Methods: A retrospective case-control study was performed between the years 2017-2018 on two groups of newborns, recording details of outcome of live born babies born to diabetic and non-diabetic mothers.Results: Data were extracted from medical records, and the descriptive and analytical statistics of this information was duly applied. in a total of 50 studied infants, 40 cases (80%) of cardiovascular anomalies have been diagnosed. Most of the cardiac anomaly was hypertrophic cardiomyopathy. The incidence of cardiovascular anomalies in infants of diabetic mothers is significantly higher than the infants of non-diabetic mothers (P=0.002). The type of maternal diabetes (diabetes mellitus, overt or gestational diabetes) did not bring about any significant difference in the incidence of cardiac malformations in infants (P=0.406).Conclusions: The incidence of cardiovascular anomalies in infants of diabetic mothers is significantly higher than the infants of non-diabetic mothers. Many of the infants were asymptomatic and therefore clinical examination and follow up in infants of diabetic mothers is important.

scholarly journals Is head to chest circumference ratio a better detector of macrosomia in infants of diabetic mothers as compared to birth weight >4000g?

2017 ◽  
Vol 4 (6) ◽  
pp. 2120
Author(s):  
Priya Jose ◽  
Jenifer Vani ◽  
Peter Prasanth Kumar Kommu ◽  
Satish Korah Kuruvila ◽  
Lalitha Krishnan
Keyword(s):  
Birth Weight ◽  
Pearson Correlation ◽  
Cross Sectional Study ◽  
Chest Circumference ◽  
College Hospital ◽  
Cross Sectional ◽  
Infants Of Diabetic Mothers ◽  
Medical College ◽  
Index Ratio ◽  
Diabetic Mothers

Background: In populations with a high incidence of low birth weight, a macrosomia index (ratio of head /chest circumference) may better detect infants of diabetic mothers rather than a birth weight of ≥4000g. The objective of this study was to correlate Macrosomia Index ≤1 (MI) with maternal HbA1c at delivery.Methods: Prospective cross-sectional study in a Medical College Hospital in South India from November 2012 to March 2014.  Study subjects were 715 term consecutive, mother/neonate pairs, booked, inborn and singleton deliveries. Birth weight, head and chest circumference of neonates, and maternal HbA1c at delivery were measured. The calculated macrosmia index (MI) was correlated with maternal HbA1c. Pearson correlation and odd’s ratio were calculated.Results: Of 715 mothers, 68.3% (488/715) had HbA1c >5.4% (range 4.2 to 10.5%), although only 32.7% (234/715) were categorized as gestational diabetics in pregnancy. Odds of Macrosomia Index ≤1 in neonates with maternal HbA1c > 5.4% was 7 times (95%CI: 3.2-15.4) as compared to that of neonates of mothers with HbA1c ≤ 5.4 (p<0.001). 13.4% (96/715) of neonates had MI ≤1 but only 1.4% (10/715) had birth weight of ≥4000g.Conclusions: MI ≤1 correlated with an HbA1c of >5.4% at delivery. Hence, in addition to birth weight ≥4000g, MI ≤1 should also be used to detect macrosomia in infants of diabetic mothers. 

Anthropometric data, fetal and neonatal complications in infants of diabetic mothers. Results of a 10-year retrospective study

2013 ◽  
Vol 154 (5) ◽  
pp. 172-177 ◽  
Author(s):  
Katalin H. Nagy ◽  
János Pomucz ◽  
Richárd Varga ◽  
Edit Szabó ◽  
Gyula Soltész
Keyword(s):  
Congenital Malformations ◽  
Distress Syndrome ◽  
Diabetes Management ◽  
Neonatal Unit ◽  
Cardiac Complications ◽  
Anthropometric Data ◽  
Neonatal Complications ◽  
Infants Of Diabetic Mothers ◽  
Adverse Neonatal Outcomes ◽  
Diabetic Mothers

Introduction: Disturbances in carbohydrate metabolism during pregnancy may result in harmful fetal and neonatal consequences. Objectives: To assess the fetal and neonatal complications of pregnancy in mothers with gestational and pregestational diabetes during a 10-year period in a county hospital in Hungary. Methods: Retrospective analysis of infants of diabetic mothers admitted to the neonatal unit between 2001 and 2010. Results: 32% of the infants were transferred to the neonatal unit. Neonatal macrosomia (birth weight >90 centile) was observed in one quarter of the infants. 39% of the infants developed hypoglycemia (blood glucose <2.6 mmol/l), in the majority of the cases within the first 8 hours. Hypoglycaemia was symptomatic in 55% of the infants. Hypocalcemia was observed in 17%, hyperviscosity in 23%, hyperbilirubinaemia in 32%, respiratory distress syndrome and/or transient tachypnoe in 22% and cardiac complications in 13% of the infants. 10% of the inafnts were affected with birth injuries. Congenital anomalies were seen in 17% of the cases, and severe malformations were present in 4% of the infants. Conclusions: Despite modern diabetes management, there is still a higher incidence of fetal macrosomia, adverse neonatal outcomes and a higher rate of severe congenital malformations in neonates of diabetic mothers. Orv. Hetil., 2013, 154, 172–177.

scholarly journals Incidence and Glycemic Status of Infants of Diabetic Mothers among 189 Hospitalized Low Birth Weight Babies

2017 ◽  
Vol 5 (1) ◽  
pp. 4-8
Author(s):  
Ashith Chandra Das ◽  
Md Tarek Azad ◽  
Nure Ishrat Nazme ◽  
Jannatul Ferdush Chowdhury ◽  
Zainab Rahman ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Cross Sectional Study ◽  
College Hospital ◽  
Cross Sectional ◽  
Infants Of Diabetic Mothers ◽  
Diabetic Mothers

Background: The prevalence of gestational diabetes mellitus (GDM) is 9.7% in Bangladesh. Infants of diabetic mothers (IDM) have a significant chance to develop various complications including glucose instability.Objective: To find out the incidence of IDM among low birth weight (LBW) babies and their relation with blood glucose level during 1st 48 hours of life.Materials and method: This cross sectional study was conducted from July 2012 to June 2013 on 189 LBW babies with birth weight <2500 gram up to 1000 gram admitted within 3 hours of life in the neonatal unit of Jalalabad Ragib Rabeya Medical College Hospital, Sylhet, Bangladesh. Detailed history including maternal history of GDM was taken. Blood glucose level was done during admission and at 3 to <6 hours of age, 6 to <24 hours of age and 24-48 hours of age.Results: Among 189 cases, male baby were 136 and female baby were 53. Preterm babies were 49.2% and term babies were 50.8%. Most of the newborn babies were delivered at hospital (78.3%) and by vaginal delivery (75.1%). Among LBW babies, 5% were infants of diabetic mothers. Hypoglycemia was present in 33.3% of infants of diabetic mothers which was significantly higher than infants of non-diabetic mothers (5.6%) within 3 hours of age.Conclusion: Infants of diabetic mothers may present as LBW and may be delivered prematurely and they have high incidence of hypoglycemia during early periods of life.Delta Med Col J. Jan 2017 5(1): 4-8

scholarly journals Assessment of Subtle Myocardial Dysfunction in Asymptomatic Infants of Diabetic Mothers

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
A A Kotby ◽  
W M Elguindy ◽  
N M S Soliman ◽  
S A Aboelmaati
Keyword(s):  
Myocardial Function ◽  
Heart Diseases ◽  
Myocardial Dysfunction ◽  
Tissue Doppler ◽  
Doppler Imaging ◽  
Cross Sectional ◽  
Infants Of Diabetic Mothers ◽  
Cardiac Functions ◽  
Hospital Pediatric ◽  
Diabetic Mothers

Abstract Background Cardiovascular abnormalities in infants of diabetic mothers (IDMS) occur in the form of congenital heart diseases (CHD), and hypertrophic cardiomyopathy (HCM). Aim of the Work We hypothesized that two dimensional speckle tracking imaging and pulsed wave tissue Doppler imaging (TM) may uncover subtle myocardial dysfunction in asymptomatic IDMs. Patients and Methods This study was a cross sectional descriptive study conducted at Ain shams University Children’s Hospital Pediatric cardiology unit during the period from June 2017 till January 2018. Thirty IDMs were recruited. IDMs with CHD and HCM were excluded. We further subdivided them into 2 groups; Infants of gestational diabetic mothers (IGDM) and infants of pregestational diabetic mothers (IPGDM). They were all examined using TDI and STI echocardiography in the first week of life. This group was compared to a group of age and sex matched healthy controls. Results All IDMs had normal cardiac dimensions and global cardiac functions as controls, IVS (P = 0.434), LVED (P = 0.318), EF (P = 0.291), LVFS(P = 0.644) and GLS(P = 0.240). However, evidence of LV dysfunction proved by increased Tei index (p = 0.018). This subtle affection of myocardial function was more prominent in infants of IPGDM when compared to IGDMs (P = 0.004). Conclusion Subtle affection of myocardial functions may occur in IDMs even in the absence of morphological cardiac changes. This was detected by TDI. Neither conventional assessment of myocardial functions, nor STI are sensitive tools in detecting these changes. IPGDMs are at risk of more profound affection of myocardial function than infants of IGDMs.

FAMILIAL DIABETES AND PERINATAL MORTALITY IN INFANTS OF DIABETIC MOTHERS

1961 ◽  
Vol 37 (3) ◽  
pp. 441-444
Author(s):  
A. Nygaard ◽  
M. Felbo ◽  
J. Pedersen
Keyword(s):  
Perinatal Mortality ◽  
High Mortality ◽  
Term Treatment ◽  
Infants Of Diabetic Mothers ◽  
Long Term Treatment ◽  
Diabetic Mothers

ABSTRACT In a study of 173 pregnancies in 130 diabetic mothers of White's groups B, C and D who had received long-term treatment during pregnancy, the authors found cases of diabetes – in addition to the mother – in the maternal family, in the father and his family, or in the maternal as well as paternal family in a total of 100 pregnancies (57 %). The perinatal mortality was only slightly – and not significantly – higher among infants whose families included other diabetics than the mother. This higher mortality was found only among male infants of whom there was a preponderance in pregnancies with familial diabetes, but this was also not statistically significant. Thus, the result indirectly indicates that the primary cause of the high mortality among the infants of diabetic women must be the fact that the foetus develops in a diabetic environment.

Sign in / Sign up

Export Citation Format

Share Document