Comparative Study between Fixed Dose of Hyperbaric Bupivacaine and Dose Related to Height Used in Spinal Anesthesia for Caesarean Section in Normal and Pre-Eclamptic Patients

This research is a method review type, comparative study between the effects of General anesthesia versus those of spinal anesthesia during caesarean section on the newborns and the mother undergoing cesarean section. The variables considered in the study included patient family history, patient medical history, status of patient during pregnancy, age of patient, and emergency or planned cesarean. Both general and spinal methods of anesthesia had differing results in multiple aspects and effects both during and after the surgery. However, pros of spinal anesthesia topped those of general anesthesia and is therefore the more favorable method of anesthesia.

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The effect of height and weight adjusted dose of intrathecal hyperbaric bupivacaine for elective caesarean section

Journal of Nepal Medical Association ◽

10.31729/jnma.17 ◽

2011 ◽

Vol 51 (181) ◽

Cited By ~ 3

Author(s):

A Subedi ◽

M Tripathi ◽

BK Bhattarai ◽

PK Gupta ◽

K Pokharel ◽

...

Keyword(s):

Caesarean Section ◽

Spinal Anesthesia ◽

Elective Caesarean Section ◽

Onset Time ◽

Distinct Advantage ◽

Spinal Block ◽

Hyperbaric Bupivacaine ◽

Number Of Patients ◽

Block Level ◽

Adjusted Dose

Introduction: The study compared spinal anesthesia using intrathecal hyperbaric bupivacaine between height and weight adjusted dose and fi xed dose during caesarean section. Methods: A hundred parturients, who had given their consent and were scheduled for elective caesarean section under spinal anesthesia, were randomly assigned into two groups. We adjusted the intrathecal dose of heavy bupivacaine (0.5 %) according to the height and weight of patients (Group AD) from Harten’s dose chart developed from the Caucasian parturients and the fi xed dose (2.2 ml) was used in Group FD patients. Keeping the observer blinded to the study groups, the onset time to sensory block up to T5, haemodynamic changes, side effects, and fetal outcome were observed. Results: The median onset time of spinal block in Group FD was faster than in Group AD (6 min vs. 4 min; p = 0.01). The spinal block level extended above T3 level in a signifi cantly (p < 0.05) larger number of patients 12 (24 %) in Group FD than in one (2 %) patient in Group AD. A signifi cantly (p < 0.05) larger number of patients, 32, (64 %) in Group FD had hypotension than in 15 (30 %) patients in Group AD. The lowest recorded SAP (101 ± 6 mm Hg) in Group AD was higher than in Group FD (96 ± 6.7 mm Hg). Nausea and vomiting were more pronounced in Group FD patients. Conclusions: The bupivacaine dose was signifi cantly reduced on its dose adjustment for the body weight and height of patients for cesearean section. This adjusted-dose use suitably restricted spinal block level for cesarean section with a distinct advantage of less hypotension and with a similar neonatal outcome as fi xed compared with the dose use. keywords: caesarean section; low-dose hyperbaric bupivacaine; spinal anesthesia.

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Comparison of Efficacy of Intrathecal Fentanyl versus Nalbuphine with Ropivacaine in Spinal Anesthesia for Postoperative Analgesic Effect following Lower Segment Caesarean Section- A Randomized Comparative Study

Journal of Medical Science And clinical Research ◽

10.18535/jmscr/v9i10.04 ◽

2021 ◽

Vol 09 (10) ◽

Author(s):

Dr Neha Khatri ◽

Keyword(s):

Caesarean Section ◽

Comparative Study ◽

Spinal Anesthesia ◽

Analgesic Effect ◽

Lower Segment ◽

Lower Segment Caesarean Section

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763 ROLE OF MIDAZOLAM ADDED TO LOW DOSE HYPERBARIC BUPIVACAINE IN SUB-ARACHNOID BLOCK FOR LOWER UTERINE CAESAREAN SECTION - A COMPARATIVE STUDY

European Journal of Pain ◽

10.1016/s1090-3801(06)60766-0 ◽

2006 ◽

Vol 10 (S1) ◽

pp. S199-S199

Author(s):

A.K.M. Akhtaruzzaman ◽

A.K. Agarwal ◽

K.M. Iqbal

Keyword(s):

Caesarean Section ◽

Comparative Study ◽

Low Dose ◽

Hyperbaric Bupivacaine

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Comparison of commonly used vasopressors for treating hypotension after spinal anaesthesia in elective lower abdominal surgery: a randomized, observational, case-control study

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20191546 ◽

2019 ◽

Vol 7 (5) ◽

pp. 1479

Author(s):

Pradeep Kumari ◽

Sifna Tahir ◽

Haveena Kumari ◽

Altaf Ahmad Mir

Keyword(s):

Blood Pressure ◽

Caesarean Section ◽

Spinal Anesthesia ◽

Elective Caesarean Section ◽

Spinal Block ◽

Hyperbaric Bupivacaine ◽

Time Intervals ◽

Significant Difference ◽

Single Bolus Dose ◽

The Mean

Background: During caesarean section hypotension due to spinal block is secondary to the sympathetic blockade and aorto-caval compression by the uterus. It can have important consequences for the mother and may affect neonatal outcome. The present study was aimed to compare intravenous bolus doses of phenylephrine and ephedrine to treat maternal hypotension during spinal block for elective caesarean section.Methods: After fulfilling the inclusion criteria, 100 parturient were randomly allocated into two groups of fifty each. For spinal anesthesia lumber puncture was done and 12.5mg, 0.5% hyperbaric bupivacaine was given intra-thecally. In this observational study, patients who developed hypotension under spinal anesthesia were selected for the study. According to their group, patients received either ephedrine 6mg (Group E) or phenylephrine 75µg (Group P) as vasopressor. During the study, number of vasopressor boluses, hemodynamic response and time taken to recover from hypotension was noted.Results: Ephedrine and phenylephrine were used in the mean doses of 6.72±1.97mg and 91.5±31.38µg respectively. In 88% parturient single bolus dose of ephedrine was effective in treating hypotension while phenylephrine was effective in 78% parturient. There was no significant difference observed in total number of boluses used. No significant difference was seen in mean systolic blood pressure, mean diastolic blood pressure and mean arterial pressure over a given period of time in Group E and Group P. Mean systolic BP was less than 20% when compared to baseline in both the groups at different time intervals. In Group P the mean heart rate was significantly lower as compared to the Group E (p<0.05).Conclusions: Intravenous phenylephrine and ephedrine are both similar in performance in treating hypotension after spinal anesthesia for elective caesarean section and the hypotensive control offered is comparable.

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