scholarly journals Determination of acute oral toxicity of tetrahydropyridone and hexahydroquinoline individual derivatives, derivatives of α-cyanothioacetamide

2019 ◽  
pp. 96-103
Author(s):  
Igor V. Bibik ◽  
Mikhail V. Korokin ◽  
Sergey G. Krivokolysko ◽  
Elena Yu. Bibik ◽  
Konstantin A. Frolov ◽  
...  
Keyword(s):  
Acute Oral Toxicity ◽  
Oral Toxicity ◽  
Derivatives Of

Investigation of antiulcer activity of Pergularia extensa Linn

2020 ◽  
Vol 9 (2) ◽  
pp. 23-26
Author(s):  
Pavani C H
Keyword(s):  
Cardiac Glycosides ◽  
Methanol Extract ◽  
Methanolic Extract ◽  
Antiulcer Activity ◽  
Acute Oral Toxicity ◽  
Gastric Lesions ◽  
Oral Toxicity ◽  
Control Groups ◽  
Dose Dependent

This study was based on determination of the antiulcer activity from methanol extract was prepared by using barks of pergularia extensa linn.. Priliminary investigations showed presence of saponins, terpenes, cardiac glycosides, alkaloids and sterols. Based on OECD-423 Guidelines, the pharmacology and acute oral toxicity studies were conducted by using methanolic extract. Ulcer development was prevented by Tannins because of their vasoconstriction effects and due to protein precipitation. Similarly, the Methanolic extract of Pergularia extensa Linn shows triterpenoids and saponins. The phytoconstituents are present in the extract and these could be possible agents which are involved in order to prevent gastric lesions induced by aspirin. When compared to ulcerative control groups, this Pergularia extensa Linn., shows a dose dependent curative ratio. The extracts exhibited an inhibition percentage of 27.18, 45.47 and 61.28 at doses of 100, 200 and 400mg/kg doses respectively. 

Acute Oral Toxicity Determination of Methyl Pyridyl Ketone in the Rat

1992 ◽  
Vol 11 (6) ◽  
pp. 681-681 ◽  
Author(s):  
A. C. Costello ◽  
R. C. Myers ◽  
C. E. Manderfield ◽  
T. G. Osimitz
Keyword(s):  
Acute Oral Toxicity ◽  
Oral Toxicity

Determination of the acute oral toxicity of theophylline in conscious dogs

1988 ◽  
Vol 11 (4) ◽  
pp. 381-389 ◽  
Author(s):  
I.J. MUNSIFF ◽  
B.C. MCKIERNAN ◽  
C. A. NEFF-DAVIS ◽  
G. D. KORITZ
Keyword(s):  
Conscious Dogs ◽  
Acute Oral Toxicity ◽  
Oral Toxicity

Acute Oral Toxicity Determination of Acetylcyclopentanone in the Rat

1992 ◽  
Vol 11 (6) ◽  
pp. 680-680
Author(s):  
A. C. Costello ◽  
R. C. Myers ◽  
C. E. Manderfield ◽  
T. G. Osimitz
Keyword(s):  
Acute Oral Toxicity ◽  
Oral Toxicity

scholarly journals Acute Oral Toxicity of Tetrodotoxin in Mice: Determination of Lethal Dose 50 (LD50) and No Observed Adverse Effect Level (NOAEL)

Toxins ◽  
2017 ◽  
Vol 9 (3) ◽  
pp. 75 ◽  
Author(s):  
Paula Abal ◽  
M. Louzao ◽  
Alvaro Antelo ◽  
Mercedes Alvarez ◽  
Eva Cagide ◽  
...  
Keyword(s):  
Adverse Effect ◽  
Lethal Dose ◽  
Acute Oral Toxicity ◽  
Oral Toxicity ◽  
Adverse Effect Level ◽  
Effect Level

scholarly journals Determination of Acute Oral Toxicity of Flumethrin in Honey Bees

2012 ◽  
Vol 105 (6) ◽  
pp. 1890-1894 ◽  
Author(s):  
H. H. Oruc ◽  
J. M. Hranitz ◽  
A. Sorucu ◽  
M. Duell ◽  
I. Cakmak ◽  
...  
Keyword(s):  
Honey Bees ◽  
Acute Oral Toxicity ◽  
Oral Toxicity
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