Clinical Experience of Clozapine†-Induced Neutropenia in the UK

Drug Safety ◽  
1992 ◽  
Vol 7 (Supplement 1) ◽  
pp. 26-32 ◽  
Author(s):  
P. A. Veys ◽  
S. Wilkes ◽  
S. Shah ◽  
R. Noyelle ◽  
A. V. Hoffbrand
Keyword(s):  
BMJ Open ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. e034692
Author(s):  
Mitesh Patel ◽  
Siang Ing Lee ◽  
Nick J Levell ◽  
Peter Smart ◽  
Joe Kai ◽  
...  

ObjectivesTo explore healthcare professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis.SettingUK nationwide.Participants20 qualified HCPs, who had a minimum of 2 years clinical experience as an HCP in the national health service and had managed a clinical case of suspected cellulitis of the lower limb in the UK. HCPs were recruited from departments of dermatology (including a specialist cellulitis clinic), general practice, tissue viability, lymphoedema services, general surgery, emergency care and acute medicine. Purposive sampling was employed to ensure that participants included consultant doctors, trainee doctors and nurses across the specialties listed above. Participants were recruited through national networks, HCPs who contributed to the cellulitis priority setting partnership, UK Dermatology Clinical Trials Network, snowball sampling where participants helped recruit other participants and personal networks of the authors.Primary and secondary outcomesPrimary outcome was to describe the key clinical features which inform the diagnosis of lower limb cellulitis. Secondary outcome was to explore the difficulties in making a diagnosis of lower limb cellulitis.ResultsThe presentation of lower limb cellulitis changes as the episode runs its course. Therefore, different specialties see clinical features at varying stages of cellulitis. Clinical experience is essential to being confident in making a diagnosis, but even among experienced HCPs, there were differences in the clinical rationale of diagnosis. A group of core clinical features were suggested, many of which overlapped with alternative diagnoses. This emphasises how the diagnosis is challenging, with objective aids and a greater understanding of the mimics of cellulitis required.ConclusionCellulitis is a complex diagnosis and has a variable clinical presentation at different stages. Although cellulitis is a common diagnosis to make, HCPs need to be mindful of alternative diagnoses.


2010 ◽  
Vol 7 (4) ◽  
pp. 423-425 ◽  
Author(s):  
Thumuluru Kavitha Madhuri ◽  
Dimitri Papatheodorou ◽  
Anil Tailor ◽  
Christopher Sutton ◽  
Simon Butler-Manuel

Thorax ◽  
2000 ◽  
Vol 55 (12) ◽  
pp. 1052-1057 ◽  
Author(s):  
S R Johnson
Keyword(s):  

2014 ◽  
Vol 96 (6) ◽  
pp. 198-201 ◽  
Author(s):  
GM Tierney ◽  
S Tou ◽  
J Hender ◽  
JN Lund

The number of emergency admissions to hospital in the UK has been increasing for many years. The cause is multifactorial and relates to increasing population age and associated comorbidity, changes in community medical emergency cover, patient expectations and decreased clinical experience of junior medical staff. Beds occupied by emergency patients within a constrained total lead inevitably to cancellation of procedures for elective patients.


Thorax ◽  
2012 ◽  
Vol 67 (Suppl 2) ◽  
pp. A48.2-A49 ◽  
Author(s):  
H Parfrey ◽  
C Leonard ◽  
MA Gibbons ◽  
E Harris ◽  
R Frank ◽  
...  

2019 ◽  
Vol 20 (4) ◽  
pp. 207-216 ◽  
Author(s):  
Manuel Gomez Serrano ◽  
Sharmila Patel ◽  
Robert Harris ◽  
David Selvadurai
Keyword(s):  

1998 ◽  
Vol 2 (3) ◽  
pp. 195-201 ◽  
Author(s):  
David Baldwin ◽  
Chris Hawley ◽  
Elemer Szabadi ◽  
Judith Burgess ◽  
Joan Thomson ◽  
...  

2013 ◽  
Vol 95 (2) ◽  
pp. 93-95 ◽  
Author(s):  
C Richards ◽  
J Barrett

Introduction In the UK, funding for a bilateral mastectomy (BLM) and associated chest recontouring for female-to-male transsexuals (trans men) has been rejected by some funding authorities on a number of unsustainable grounds. Methods As funding is increasingly an important area for both surgeons and referrers, we undertook a review of the small amount of literature pertaining to this issue and considered it in light of our clinical experience of this group. Findings The literature showed that BLM is necessary for trans men to live safely and effectively in their reassigned gender role, and further that it acts as a prophylaxis against distress, ameliorates extant distress as well as providing improved quality of life and global functioning for this patient group.


Sign in / Sign up

Export Citation Format

Share Document