Growth Hormone Therapy and Quality of Life in Adults and Children

2004 ◽  
Vol 22 (8) ◽  
pp. 499-524 ◽  
Author(s):  
Deborah J Radcliffe ◽  
Joseph S Pliskin ◽  
J B Silvers ◽  
Leona Cuttler
Keyword(s):  
Quality Of Life ◽  
Growth Hormone ◽  
Hormone Therapy ◽  
Growth Hormone Therapy ◽  
Adults And Children

Quality of Life after Growth Hormone Therapy and Induced Puberty in Women with Turner Syndrome

2006 ◽  
Vol 148 (1) ◽  
pp. 95-101 ◽  
Author(s):  
Ellen M.N. Bannink ◽  
Hein Raat ◽  
Paul G.H. Mulder ◽  
Sabine M.P.F. de Muinck Keizer-Schrama
Keyword(s):  
Quality Of Life ◽  
Growth Hormone ◽  
Hormone Therapy ◽  
Turner Syndrome ◽  
Growth Hormone Therapy

scholarly journals Ocena satysfakcji rodziców z leczenia ludzkim rekombinowanym hormonem wzrostu dzieci z somatotropinową niedoczynnością przysadki

2020 ◽  
Vol 5 (4) ◽  
pp. 38-53
Author(s):  
Lech Grzelak ◽  
◽  
Anna Wiśniewska ◽  
Robert Ślusarz ◽  
◽  
...  
Keyword(s):  
Quality Of Life ◽  
Growth Hormone ◽  
Hormone Therapy ◽  
Growth Hormone Therapy ◽  
Duration Of Treatment ◽  
Recombinant Growth Hormone ◽  
Screen Questionnaire ◽  
Treat Ment ◽  
Satisfaction With Treatment

Introduction. Short stature is a term for a child's height below two standard deviations from the norms adopted for sex and age. In Poland, treatment with recombinant growth hormone of somatotropin hypopituitarism is reimbursed under the National Health Fund drug programs. Administration of growth hormone in the form of daily injections is cumbersome and requires the in-volvement of the whole family in the treatment process. The multidirectional action of GH improves the quality of life of small patients. Aim. The aim of the study is to analyze parents' satisfaction with growth hor-mone treatment in children with somatotropin hypopituitarism. Materiał and methods. The study involved 69 parents of children with so-matotropin hypopituitarism treated with growth hormone at the Department of Pediatrics, Endocrinology, Diabetology and Pediatric Neurology at the Chil-dren"s Hospital in Torun. The research used the own questionnaire and KID-SCREEN questionnaire for parents. Results. Parents of children with somatotropin hypopituitarism are satisfied with the treatment with recombinant growth hormone and evaluate the treat-ment positively. During growth hormone therapy, they highly estimate the quality of their children’s lives. There is a correlation between parents' as-sessment of growth hormone therapy and the change in their children's quality of life. Conclusions. Satisfaction with treatment recombinant growth hormone de-pends on the duration of treatment, achieved growth results and the child's age.

scholarly journals Growth hormone therapy and Quality of Life: possibilities, pitfalls and mechanisms

2003 ◽  
Vol 179 (3) ◽  
pp. 311-333 ◽  
Author(s):  
KL Hull ◽  
S Harvey
Keyword(s):  
Quality Of Life ◽  
Growth Hormone ◽  
Metabolic Pathways ◽  
Intrauterine Growth Retardation ◽  
Growth Hormone Therapy ◽  
Intrauterine Growth ◽  
Pulmonary Physiology ◽  
Short Children ◽  
The Relationship

The actions of growth hormone (GH) are not restricted to growth: GH modulates metabolic pathways as well as neural, reproductive, immune, cardiovascular, and pulmonary physiology. The importance of GH in most physiological systems suggests that GH deficiency at any age would be associated with significant morbidity. However, prior to the advent of recombinant GH, cadaver-derived GH was only used therapeutically to correct the height deficit, and thereby hypothetically improve quality of life (QoL), in GH-deficient children. Physicians now have access to unlimited, albeit expensive, supplies of recombinant GH, and are considering the advisability of GH replacement or supplementation in other patient populations. This paper analyses studies investigating the relationship between GH and QoL in GH-deficient children or adults, in GH-replete short children suffering from idiopathic short stature, Turner syndrome, or intrauterine growth retardation and in GH-deficient or replete elderly adults. Possible mechanisms by which GH might improve QoL at neural and somatic sites are also proposed.

Growth Hormone Therapy in Adults and Children

1999 ◽  
Vol 341 (16) ◽  
pp. 1206-1216 ◽  
Author(s):  
Mary Lee Vance ◽  
Nelly Mauras
Keyword(s):  
Growth Hormone ◽  
Hormone Therapy ◽  
Growth Hormone Therapy ◽  
Adults And Children

scholarly journals Diagnosis and Management of Neuroendocrine Disorders of Survivors of Brain Tumors

2021 ◽  
pp. 1-9
Author(s):  
Dana Erickson ◽  
Diane Donegan
Keyword(s):  
Quality Of Life ◽  
Growth Hormone ◽  
Brain Tumors ◽  
Hormone Deficiency ◽  
Adult Growth ◽  
Adults And Children ◽  
Receive Treatment ◽  
High Level

Advances in the treatment of brain tumors have led to an increase in the number of survivors of this disease. Consequently, the long-term complications associated with past and current treatments are becoming more apparent. Of relevance to patients who receive treatment of brain tumors are the potential neuroendocrine complications that develop either acutely or several years following treatment. Presentation may differ between adults and children (e.g., short stature or adult growth hormone deficiency) but in both settings can complicate treatment and impact quality of life. The risk for the development of these complications depends on the location of the tumor (proximity to the pituitary/hypothalamus) and/or the treatment delivered (chemotherapy/surgery/radiation). Given the potential overlap in symptoms attributable to the underlying brain tumor and neuroendocrine dysfunction, a high level of suspicion, appropriate investigation, and administration of treatment may reduce morbidity and mortality for patients with brain tumors experiencing neuroendocrine dysfunction.

Sign in / Sign up

Export Citation Format

Share Document