Visual spatial gnosis and visual constructive activity in patients before and after embolization of intracranial aneurysms

2018 ◽  
Vol 22 (2) ◽  
pp. 47
Author(s):  
Vadim G. Postnov ◽  
Evgeny A. Levin ◽  
Kirill Yu. Orlov ◽  
Roman S. Kiselev

<p><strong>Aim.</strong> The study was aimed at examining visual spatial gnosis and visual constructive activity in patients with cerebral aneurysms of anterior circulation before and after endovascular embolization with flow-diverter stents.</p><p><strong>Methods.</strong> Nineteen patients were examined before and after embolization of aneurysms. Patients were asked to perform 5 tests: determining the time on an “empty” dial (without numbers); setting the clock hands on an “empty” dial for the given time; drawing a human figure using the left and right hands; copying the picture of a house from the sample; copying from memory the Rey–Taylor and the Rey–Osterrieth complex figures.</p><p><strong>Results.</strong> Group differences between single measures obtained before and after the surgery were not statistically significant in any of the tests. At the same time, dependency on the hand used for drawing was nearly significant for postoperative changes in human figure drawing quality: the quality of figures drawn using the right hand became on average better after surgery, while the figures drawn using the left hand got worse. Postoperative individual changes demonstrated a “mosaic” pattern for the whole set of the tests, i.e. in most patients the results improved in some test(s) but degraded in other(s) and patterns of these changes differed between the patients.</p><p><strong>Conclusion.</strong> Postoperative changes in visual spatial gnosis and visual constructive activity are of a “mosaic” nature, supposedly due to multiple brain microlesions without certain localizations. At the same time, the differences between changes in the quality of human figures drawn using the right and left hands could be a sign of relative prevalence of the right hemisphere lesions. But in general, there were no significant postoperative changes in the brain integrative activity within the visual-spatial modality after endovascular aneurysm surgery with flow-diverter stents.</p><p>Received 13 March 2018. Revised 17 April 2018. Accepted 20 April 2018.</p><p><strong>Funding:</strong> The study did not have sponsorship.</p><p><strong>Conflict of interest:</strong> The authors declare no conflict of interest.</p><p><strong>Author contributions</strong><br />Conception and study design: V.G. Postnov, K.Yu. Orlov<br />Data collection: V.G. Postnov, R.S. Kiselev<br />Data analysis: V.G. Postnov, E.A. Levin<br />Drafting the article: V.G. Postnov, E.A. Levin, R.S. Kiselev<br />Final approval of the version to be published: V.G. Postnov, E.A. Levin, K.Yu. Orlov, R.S. Kiselev<br /><br /></p>

2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
Chiharu Niki ◽  
Takashi Maruyama ◽  
Yoshihiro Muragaki ◽  
Takatsune Kumada

Background. Perseveration has been observed in a number of behavioural contexts, including speaking, writing, and drawing. However, no previous report describes patients who show perseveration only for drawing a human figure.Objective. The present report describes a group of patients who show body awareness-related cognitive impairment during a human figure drawing task, a different presentation from previously described neuropsychological cases.Methods. Participants were 15 patients who had a frontal lobe brain tumour around the insula cortex of the right hemisphere and had subsequently undergone a neurosurgical resective operation. Participants were asked to draw a human figure in both “hands-down” and “hands-up” configurations.Results. Eight of the 15 patients drew a human figure with six fingers during the “hands-up” and the “hands-down” human figure drawing tasks (one patient drew eight fingers). A statistical analysis of potential lesion areas revealed damage to the right anterior frontal insula and operculum in this group of patients relative to the five-finger drawing group.Conclusions. Our findings reveal a newly described neuropsychological phenomenon that could reflect impairment in attention directed towards body representations.


2021 ◽  
Vol 92 (8) ◽  
pp. A18-A18
Author(s):  
Maria Teixeira-Dias ◽  
Amber Kaur Dadwal ◽  
Graham Blackman

Objectives/AimsFregoli syndrome is a rare delusion characterised by the misidentification of an individual, typically of someone who the patient has an emotional link towards. The pathoaetiology of Fregoli syndrome remains largely a mystery, however, it has been described in patients experiencing either a primary or secondary (organic) psychosis. We sought to compare the neuropsychiatric features of Fregoli syndrome in primary and secondary psychosis.MethodsA patient-level meta-analysis was conducted. Five databases were searched for any descriptions of Fregoli syndrome. The patients and the psychotic episodes details alongside the co-occurring neuropsychiatric features and treatment responses were extracted. A risk of bias assessment was carried by scoring the methodological quality of all case studies. Random-effects models were used to pool the data and odds ratios and 95% confidence intervals were estimated for each of the neuropsychiatric features extracted between primary and secondary psychoses groups.ResultsA total of 119 patients (62 with primary psychosis, 50 with secondary psychosis and 7 with mixed or unknown aetiology) with Fregoli syndrome were identified in the English literature. Persecutory features were more likely to occur in patients with primary Fregoli syndrome (OR = 0.26, 95% CI[0.10;0.67], p < 0.01). In addition, Fregoli syndrome in the context of a first-episode psychosis (OR = 11.00, 95% CI [2.45;49.39], p < 0.01) and in the presence of neuroimaging abnormalities (OR = 20.19, 95% CI [4.36; 93.47], p < 0.01) was significantly associated with secondary aetiology. Patients in the secondary psychosis group (n=14) showed more right hemisphere lesions than patients in the primary psychosis group (n=1), however this trend was not significant (p = 0.10). Furthermore, no statistical differences between psychoses groups were found for the demographic, clinical and neurophysiological features analysed.ConclusionsThis is the first meta-analysis investigating the features of Fregoli syndrome in primary and secondary psychosis.Findings suggest that secondary causes of Fregoli syndrome are associated with a first-episode of psychosis and that neuroimaging abnormalities, particularly in the right hemisphere, are associated with a secondary organic cause.


Author(s):  
Susan A. Leon ◽  
Amy D. Rodriguez

Abstract Aprosodia is a deficit in comprehending or expressing variations in tone of voice used to express both linguistic and emotional information. Affective aprosodia refers to a specific deficit in producing or comprehending the emotional or affective tones of voice. Aprosodia is most commonly associated with right hemisphere strokes; however, it may also result from other types of brain damage such as traumatic brain injury. Although research investigating hemispheric lateralization of prosody continues, there is strong evidence that most aspects of affective prosody are directed by the right hemisphere. Disorders of emotional communication can have a significant impact on quality of life for those affected and their families. However, there has been relatively little research regarding treatment for this disorder. Recently, 14 individuals were treated for affective aprosodia using two treatments, one based on cognitive-linguistic cues and the other on imitation of prosodic modeling. Most of the participants responded to at least one of the two treatments, and a refinement of the treatments are currently underway. Because researchers are finding support for the hypothesis that expressive aprosodia can result from a motor deficit, the refined treatment incorporates principles of motor learning to enhance imitation of prosodic models, as well as cognitive-linguistic cues.


2015 ◽  
Vol 17 (suppl 5) ◽  
pp. v190.4-v191
Author(s):  
Christian Iorio-Morin ◽  
Philippe Goffaux ◽  
Maxime Descoteau ◽  
Kevin Whittingstall ◽  
David Fortin

2021 ◽  
Author(s):  
Meytal Wilf ◽  
Celine Dupuis ◽  
Davide Nardo ◽  
Diana Huber ◽  
Sibilla Sander ◽  
...  

Our everyday life summons numerous novel sensorimotor experiences, to which our brain needs to adapt in order to function properly. However, tracking plasticity of naturalistic behaviour and associated brain modulations is challenging. Here we tackled this question implementing a prism adaptation training in virtual reality (VRPA) in combination with functional neuroimaging. Three groups of healthy participants (N=45) underwent VRPA (with a spatial shift either to the left/right side, or with no shift), and performed fMRI sessions before and after training. To capture modulations in free-flowing, task-free brain activity, the fMRI sessions included resting state and free viewing of naturalistic videos. We found significant decreases in spontaneous functional connectivity between large-scale cortical networks, namely attentional and default mode/fronto-parietal networks, only for adaptation groups. Additionally, VRPA was found to bias visual representations of naturalistic videos, as following rightward adaptation, we found upregulation of visual response in an area in the parieto-occipital sulcus (POS) in the right hemisphere. Notably, the extent of POS upregulation correlated with the size of the VRPA induced after-effect measured in behavioural tests. This study demonstrates that a brief VRPA exposure is able to change large-scale cortical connectivity and correspondingly bias the representation of naturalistic sensory inputs.


2017 ◽  
Author(s):  
Helle Stangeland ◽  
Vasiliki Orgeta ◽  
Vaughan Bell

Aims and objectives: A pre-registered systematic review of post-stroke psychosis examining clinical characteristics, prevalence, diagnostic procedures, lesion location, treatments, risk factors, and long-term outcomes.Background: Neuropsychiatric outcomes following stroke are common and severely impact quality of life. Previous reviews have focused on anxiety, depression and cognitive impairment in stroke but no systematic review has yet focused on post-stroke psychosis despite clear clinical need.Methods: CINAHL, MEDLINE and PsychINFO were searched for studies on post-stroke psychosis published between 1975 and 2016. Reviewers independently selected studies for inclusion, extracted data, and rated study quality.Results: Out of 2442 references, 75 met the inclusion criteria. Average age for post-stroke psychosis was 60.8 years with slightly more males than females affected. Average psychosis onset was 7.1 months after stroke. Neurological presentation was typical for stroke but a significant minority had ‘silent strokes’. The most common psychosis was delusional disorder, followed by schizophrenia-like psychosis and mood disorder with psychotic features. Mean prevalence was 4.1% (range 0.2% – 9.9%). 12 year incidence was 6.7%. Antipsychotic medication was commonly prescribed and the most frequent outcome was complete remission. Lesions were typically right hemisphere, particularly frontal, temporal and parietal regions, as well as the right caudate nucleus. Post-stroke psychosis was associated with poor functional outcomes and high mortality. Methodological quality of the studies was poor.Conclusion: Psychosis considerably adds to illness burden of stroke. Delayed onset suggests a window for early detection and intervention. Studies on the safety and efficacy of antipsychotics in this population are urgently needed.


2019 ◽  
Author(s):  
Selene Schintu ◽  
Michael Freedberg ◽  
Stephen J. Gotts ◽  
Catherine A. Cunningham ◽  
Zaynah M. Alam ◽  
...  

ABSTRACTPrism adaptation (PA) alters spatial cognition according to the direction of visual displacement by temporarily modifying sensorimotor mapping. Right-shifting prisms (right PA) improve neglect of left space in patients, possibly by decreasing activity in the left hemisphere and increasing it in the right. Left PA shifts attention to the right in healthy individuals by an opposite mechanism. However, functional imaging studies of PA are inconsistent, perhaps because of differing activation tasks. We measured resting-state functional connectivity (RSFC) in healthy individuals before and after PA. Right, vs. left, PA decreased RSFC in the navigation network defined by the right posterior parietal cortices (PPCs), hippocampus, and cerebellum. Right PA, relative to baseline, increased RSFC between regions within both PPCs and between the PPCs and the right middle frontal gyrus, whereas left PA decreased RSFC between these regions. These results show that right PA modulates connectivity within the right-hemisphere navigation network and shifts attention leftward by increasing connectivity in the right frontoparietal network and left PA produces essentially opposite effects, consistent with the interhemispheric competition model. These finding explain the action of PA on intact cognition and will help optimize interventions in neglect patients.


2015 ◽  
Vol 34 (1) ◽  
pp. 1-10
Author(s):  
Sri Rejeki Indah Astiani ◽  
Djamaluddin Ramelan

PT Budi Makmur is one of the made leather industry that located in Yogyakarta. It processing a raw leather which from goat leather that processed into wolves, shoes, etc. PT Budi Makmur also produce water waste that flows to the river and if the waste is not produced in the right way, the waste will be very dangerous for the ecosystem in that river.The aim of this research are to know the process of the liquid waste producing leather tanning, the parameter of the liquid waste before and after through the producing process (COD, BOD, TSS dan pH) , and the condition of the liquid waste producing leather tanning.The kind of this research is descriptive. The research done by collecting the field data an laboratorium, and then analyzed and compared with the existing theory and quality of the liquid waste producing leather tanning.The result show that the source of the waste produce from the leather tranning. Liquid waste that produced is about 8.000-12.000 gallon per 1.000 wet leather pond that produced. The quality of the influent is BOD 1.946mg/lt, COD 1965mg/lt, TSS 1.774mg/ltd and pH 7.50. The quality of the effluent is BOD 98.61mg/lt, COD 100mg/lt, TSS 1130mg/lt and pH 7,49. The step of the liquid waste processing are: filtering ink, equalitation ink, sedimentation, aeration and active mud.The writer conclude that PT Budi Makmur has already optimal to decrease the content that contained in the leather-liquid waste producing but the effluent that is produced still exceed the exsisting standart quality. The suggestion to PT Budi Makmur is to more care about the liquid waste producing.


2021 ◽  
Vol 11 (12) ◽  
pp. 1644
Author(s):  
Guido Gainotti

This review evaluated if the hypothesis of a causal link between the left lateralization of language and other brain asymmetries could be supported by a careful review of data gathered in patients with unilateral brain lesions. In a short introduction a distinction was made between brain activities that could: (a) benefit from the shaping influences of language (such as the capacity to solve non-verbal cognitive tasks and the increased levels of consciousness and of intentionality); (b) be incompatible with the properties and the shaping activities of language (e.g., the relations between language and the automatic orienting of visual-spatial attention or between cognition and emotion) and (c) be more represented on the right hemisphere due to competition for cortical space. The correspondence between predictions based on the theoretical impact of language on other brain functions and data obtained in patients with lesions of the right and left hemisphere was then assessed. The reviewed data suggest that different kinds of hemispheric asymmetries observed in patients with unilateral brain lesions could be subsumed by common mechanisms, more or less directly linked to the left lateralization of language.


2021 ◽  
Author(s):  
Nicolas Bedo ◽  
Dikla Ender-Fox ◽  
Janet Chow ◽  
Linda Siegel ◽  
Urs Ribary ◽  
...  

We examined the brain networks and oscillatory dynamics, inferred from EEG recordings during a word-reading task, of a group of children in grades 4 and 5 (ages 9–11), some of whom were dyslexic. We did this in order to characterize the differences in these dynamics between typical and dyslexic readers, and to begin to characterize the effect of a phonological intervention on those differences. Dyslexic readers were recorded both before and after they participated in a FastForWord (FFW) reading training program for approximately six months and typical readers were recorded once during this period. Before FFW dyslexic readers showed (i) a bottleneck in letter recognition areas, (ii) expansion in activity and connectivity into the right hemisphere not seen in typical readers, and (iii) greater engagement of higher-level language areas, even for consonant string stimuli. After FFW, dyslexic readers evinced a significant reduction in the engagement of language processing areas, and more activity and connectivity expanding to frontal areas, more resembling typical readers. Reduction of connectivity was negatively correlated with gains in reading performance, suggesting an increase in communication efficiency. Training appeared to improve the efficiency of the alternative (bilateral) pathways already used by the dyslexic readers, rather than inducing them to create new pathways more similar to those employed by typical readers.


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