scholarly journals Plasma Brain Natriuretic Peptide as an Independent Predictor of In-Hospital Mortality after Acute Ischemic Stroke

2009 ◽  
Vol 48 (18) ◽  
pp. 1601-1606 ◽  
Author(s):  
Kensaku Shibazaki ◽  
Kazumi Kimura ◽  
Yoko Okada ◽  
Yasuyuki Iguchi ◽  
Jyunichi Uemura ◽  
...  
2013 ◽  
Vol 10 (5) ◽  
pp. 679-685 ◽  
Author(s):  
Murat Biteker ◽  
Temel Özden ◽  
Akin Dayan ◽  
Ahmet Ilker Tekkeşin ◽  
Cemile Handan Misirli

Author(s):  
Jaydip Ray Chaudhuri ◽  
Vijay Kumar Sharma ◽  
Kandadai Rukmini Mridula ◽  
Banda Balaraju ◽  
Venkata Chandra Sekher Srinivasarao Bandaru

2006 ◽  
Vol 22 (5-6) ◽  
pp. 439-444 ◽  
Author(s):  
J.K. Jensen ◽  
H. Mickley ◽  
S. Bak ◽  
L. Korsholm ◽  
S.R. Kristensen

2007 ◽  
Vol 260 (1-2) ◽  
pp. 139-142 ◽  
Author(s):  
Emanuele Di Angelantonio ◽  
Stefano De Castro ◽  
Danilo Toni ◽  
Maria Luisa Sacchetti ◽  
Francesco Biraschi ◽  
...  

2020 ◽  
Vol 8 (B) ◽  
pp. 119-124
Author(s):  
Hossam A. Mowafy ◽  
Hossam El Sherif ◽  
Khaled A. Wahab ◽  
Nora I. Abbas ◽  
Gihan El Hilaly ◽  
...  

CONTEXT: Plasma brain natriuretic peptide (BNP) levels are elevated in patients with acute ischemic stroke, particularly when accompanied by atrial fibrillation (AF). Plasma BNP might be a useful marker of vulnerability to thromboembolism in non-valvular AF patients. AIM: The aim of the present study was to assess whether the BNP level can serve as a biomarker of the left atrial (LA) thrombus in AF patients with acute ischemic stroke. SETTINGS AND DESIGN: This was a multicenter prospective cohort study. PATIENTS AND METHODS: Thirty AF patients with acute ischemic stroke were included in the study. Their transesophageal echocardiography (TEE) and BNP were assessed. RESULTS: There was a positive significant relation between serum BNP levels and LA thrombus detection by TEE. BNP with a cutoff value >498 pg/l can be used as a diagnostic biomarker for the presence of the LA thrombus. A significant positive correlation existed between serum BNP and LA diameter. Furthermore, a statistically significant positive correlation between serum BNP and AF rate and duration was found in all patients. In addition, a statistically significant inverse correlation was detected between serum BNP and direct bilirubin, international normalized ratio, and albumin. A statistically significant positive correlation existed between serum BNP and prothrombin concentration. CONCLUSION: BNP can be a good diagnostic biomarker for the detection of the LA thrombus in chronic AF patients with acute ischemic stroke.


2019 ◽  
Vol 76 (4) ◽  
pp. 373-378
Author(s):  
Angelina Skodric ◽  
Gorica Maric ◽  
Dejana Jovanovic ◽  
Ljiljana Beslac-Bumbasirevic ◽  
Darija Kisic-Tepavcevic ◽  
...  

Background/Aim. Stroke remains one of the leading causes of death and disability worldwide. The aim of the study was to determine the nursing care-associated predictors of in-hospital mortality in the patients with acute ischemic stroke (AIS) who were hospitalized at the Department of Emergency Neurology. Methods. Prospective cohort study included 59 consecutive patients with AIS admitted to the Department of Emergency Neurology, Neurology Clinic, Clinical Center of Serbia, Belgrade. The patients were followed until discharge or death. For exploring a relationship between the outcome of patients with AIS and different groups of factors, the univariate and multivariate Cox proportionate hazard regression models were used. Results. There were 32 male and 27 female patients with AIS. The mean age was 62.5 ? 15.2 years. The average duration of hospitalization was 11.1 ? 9.6 days (median 8 days; range 1?54 days). Almost 80% of patients (47/59; 79.7%) were admitted to the stroke unit, while 12 (20.3%) patients were admitted to the intensive care unit. In the univariate Cox regression analysis the significant variables (p < 0.05) were the Morse score (p = 0.030) and the type of admission unit (p = 0.029). The multivariate predictive model revealed that the type of admission unit (stroke unit vs conventional unit) [hazard ratio (HR) = 0.16; p = 0.032] was the independent predictor of in-hospital mortality in the patients with AIS. Conclusion. The results of this study showed an important role of nursing staff in the recovery of the AIS patients, as well as that admission to the stroke units versus the conventional units is the independent predictor of decreased in-hospital mortality.


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