The task of regulatory body staff reviewing and assessing a realistic large break loss-of-coolant accident evaluation model is discussed, facing the actual regulatory licensing environment related to the acceptance of the analysis of emergency core cooling system performance. Especially, focus is directed to the question of how to fulfill the requirement of quantifying the uncertainty in the calculated results when they are compared to the acceptance criteria for this system. As it is recognized that the regulation governing the loss-of-coolant accident analyses was originally developed by the United States Nuclear Regulatory Commission, a description of its evolution is presented. When using a realistic evaluation model to analyze the loss-of-coolant accident, different approaches have been used in the licensing arena. The Brazilian regulatory body has concluded that, in the current environment, the independent regulatory calculation is recognized as a relevant support for the staff decision within the licensing framework of a realistic analysis.