Design, Development and Evaluation of Chronomodulated Drug Delivery Systems of Amoxicillin Trihydrate with Enhanced Antimicrobial Activity

2013 ◽  
Vol 10 (2) ◽  
pp. 174-187 ◽  
Author(s):  
Sarwar Beg ◽  
Suryakanta Swain ◽  
Sachin Gahoi ◽  
Kanchan Kohli
2014 ◽  
Vol 11 (2) ◽  
pp. 121-127 ◽  
Author(s):  
Lia-Mara Ditu ◽  
Mariana Chifiriuc ◽  
Diana Pelinescu ◽  
Ionela Avram ◽  
Gratiela Pircalabioru ◽  
...  

2019 ◽  
Vol 295 ◽  
pp. 111649 ◽  
Author(s):  
Aamir Jalil ◽  
Mulazim Hussain Asim ◽  
Zeynep Burcu Akkus ◽  
Martin Schoenthaler ◽  
Barbara Matuszczak ◽  
...  

2015 ◽  
Vol 39 (4) ◽  
pp. 3021-3034 ◽  
Author(s):  
Kashma Sharma ◽  
Vijay Kumar ◽  
Balbir Singh Kaith ◽  
Vinod Kumar ◽  
Sudipta Som ◽  
...  

Development of colon-specific drug delivery systems for amoxicillin trihydrate and paracetamol using gum ghatti based crosslinked hydrogels.


Author(s):  
G.E. Visscher ◽  
R. L. Robison ◽  
G. J. Argentieri

The use of various bioerodable polymers as drug delivery systems has gained considerable interest in recent years. Among some of the shapes used as delivery systems are films, rods and microcapsules. The work presented here will deal with the techniques we have utilized for the analysis of the tissue reaction to and actual biodegradation of injectable microcapsules. This work has utilized light microscopic (LM), transmission (TEM) and scanning (SEM) electron microscopic techniques. The design of our studies has utilized methodology that would; 1. best characterize the actual degradation process without artifacts introduced by fixation procedures and 2. allow for reproducible results.In our studies, the gastrocnemius muscle of the rat was chosen as the injection site. Prior to the injection of microcapsules the skin above the sites was shaved and tattooed for later recognition and recovery. 1.0 cc syringes were loaded with the desired quantity of microcapsules and the vehicle (0.5% hydroxypropylmethycellulose) drawn up. The syringes were agitated to suspend the microcapsules in the injection vehicle.


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