A Review of Neuroimaging Studies on Working Memory Paradigms in Patients with Bipolar Disorder

2019 ◽  
Vol 18 (21) ◽  
pp. 1883-1892 ◽  
Author(s):  
Asen Beshkov ◽  
Mariyan Topolov ◽  
Feryhan Ahmed-Popova ◽  
Stefan Sivkov

New brain technologies including neuroimaging studies are powerful means for providing new insights into clinical and cognitive neuroscience. Bipolar disorder is a severe chronic phasic mental disease characterized by various cognitive dysfunctions. Working memory is one prominent domain of cognitive impairment in bipolar disorder. Disruptions in working memory are observed even in euthymic bipolar patients which makes it a potential endophenotypic marker for the disorder. Finding such markers may help in providing firm neurobiological basis for psychiatric nosologies and symptomatic presentations. This review aims to summarize some of the important aspects of findings from functional magnetic resonance imaging studies on the activation of brain structures in relation to working memory paradigms.

2002 ◽  
Vol 25 (6) ◽  
pp. 771-771 ◽  
Author(s):  
Elise Temple

Functional magnetic resonance imaging studies of developmental disorders and normal cognition that include children are becoming increasingly common and represent part of a newly expanding field of developmental cognitive neuroscience. These studies have illustrated the importance of the process of development in understanding brain mechanisms underlying cognition and including children in the study of the etiology of developmental disorders.


2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
S. Frangou

Current models for mood disorders and particularly bipolar disorder focus on increaesed activation within the limbic system coupled with reduced inhibitory control from the prefrontal cortex. This presentation will focus on functional magnetic resonance imaging studies that highlight limbic-prefrontal interactions in Mood Disorders and on the potential effect of antidepressants and mood stablisers on these neural networks.


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