Oxidative Halogenation of Arenes, Olefins and Alkynes Mediated by Iodine(III) Reagents

2020 ◽  
Vol 17 ◽  
Author(s):  
Luis A. Segura-Quezada ◽  
Karina R. Torres-Carbajal ◽  
Yuvraj Satkar ◽  
Kevin A. Juárez Ornelas ◽  
Narendra Mali ◽  
...  
Keyword(s):  
Functional Groups ◽  
Oxidative Reactions ◽  
Recent Advances ◽  
Oxidative Halogenation ◽  
Synthetic Transformations

: Iodine(III)-based reagents has been broadly used in oxidative reactions for the structural functionalization with several functional groups. Among the more relevant and useful synthetic transformations using these hypervalent γ 3 -reagents, it can be found the fluorination, chlorination, bromination as well as the iodination protocols. Herein, we present some of the most representatives oxidative halogenation procedures of arenes, olefins and alkynes dating from the oldest to the more recent advances in the area, highlighting the discovery and application of new iodine(III)-based halogenating species.

scholarly journals Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives

Molecules ◽  
2018 ◽  
Vol 23 (11) ◽  
pp. 2783 ◽  
Author(s):  
Shu-Guang Zhang ◽  
Chao-Gen Liang ◽  
Wei-Hua Zhang
Keyword(s):  
Functional Groups ◽  
Medicinal Chemistry ◽  
Biological Activities ◽  
Drug Molecules ◽  
Recent Advances

Indazole-containing derivatives represent one of the most important heterocycles in drug molecules. Diversely substituted indazole derivatives bear a variety of functional groups and display versatile biological activities; hence, they have gained considerable attention in the field of medicinal chemistry. This review aims to summarize the recent advances in various methods for the synthesis of indazole derivatives. The current developments in the biological activities of indazole-based compounds are also presented.

Recent advances in separators to mitigate technical challenges associated with re-chargeable lithium sulfur batteries

2019 ◽  
Vol 7 (12) ◽  
pp. 6596-6615 ◽  
Author(s):  
Masud Rana ◽  
Ming Li ◽  
Xia Huang ◽  
Bin Luo ◽  
Ian Gentle ◽  
...  
Keyword(s):  
Functional Groups ◽  
Coating Materials ◽  
Recent Advances ◽  
Lithium Sulfur Batteries ◽  
Mechanism Of Interaction ◽  
Technical Challenges ◽  
Lithium Sulfur

Different classes of coating materials with their functional groups and mechanism of interaction with PSs.

Iodine(III)-mediated synthesis of chiral α-substituted ketones: recent advances and mechanistic insights

2017 ◽  
Vol 89 (6) ◽  
pp. 781-789 ◽  
Author(s):  
Benoit Basdevant ◽  
Audrey-Anne Guilbault ◽  
Samuel Beaulieu ◽  
Antoine Jobin-Des Lauriers ◽  
Claude Y. Legault
Keyword(s):  
Quantum Chemical Calculations ◽  
Quantum Chemical ◽  
New Method ◽  
Experimental Strategy ◽  
Rapid Access ◽  
Chiral Ketones ◽  
Recent Advances ◽  
Nucleophilic Displacement ◽  
Synthetic Transformations

AbstractThe development of iodine(III)-mediated synthetic transformations has received growing interest, in particular to mediate enantioselective processes. In this class, the α-tosyloxylation of ketone derivatives using iodine(III) is a particularly powerful one, as it yields α-tosyloxy ketones – versatile chiral precursors that enable rapid access to numerous α-chiral ketones through nucleophilic displacement. Despite years of research from numerous groups, the enantioselectivities for this transformation have remained modest. Using quantum chemical calculations, we have uncovered a possible rational for the lack of selectivity. With these computational insights, we have developed an alternative experimental strategy and achieved unprecedented levels of selectivities. Applying this newfound knowledge, we have recently developed a new method to access α-halo ketones from non-ketonic precursors.

Recent advances in chemistry of phthalocyanines bearing electron-withdrawing halogen, nitro and N-substituted imide functional groups and prospects for their practical application

2019 ◽  
Vol 43 (24) ◽  
pp. 9314-9327 ◽  
Author(s):  
E. A. Kuzmina ◽  
T. V. Dubinina ◽  
L. G. Tomilova
Keyword(s):  
Functional Groups ◽  
Practical Application ◽  
Recent Advances

Herein, we present an overview of the approaches for the synthesis of phthalocyanines bearing electron-withdrawing halogen-, nitro- and N-substituted imide functional groups in different positions of the phthalocyanine macrocycle.

Recent Advances in Preparation and Application of Functionalized Mesoporous Materials

2019 ◽  
Vol 12 (3) ◽  
pp. 239-247
Author(s):  
Jianghong Liu ◽  
Xiaohang Wei ◽  
Dandan Yuan ◽  
Jingwei Ren ◽  
Jian Xue
Keyword(s):  
Heavy Metals ◽  
Functional Groups ◽  
Mesoporous Materials ◽  
Catalytic Properties ◽  
Organic Contaminant ◽  
Metal Doping ◽  
Preparation Methods ◽  
Recent Advances

Functionalized mesoporous materials are widely used in the environmental field due to their excellent adsorption and catalytic properties. The materials with different functions are obtained by modifying mesoporous materials. In this paper, the preparation methods of functional mesoporous materials with functional groups, metal doping and acid modified were presented. This review focused on the main features and applied prospects of functionalized mesoporous materials under three producing methods. Recent advances of functionalized mesoporous materials in the fields of adsorption and catalysis have been summarized. Adsorption mainly refers to the treatment of heavy metals, organic contaminant, dyestuff and CO2. Finally, the trends and application foreground of functionalized mesoporous materials were elaborated in this paper, which provided reference and guidance for the development of functional mesoporous materials.

1.13 Intramolecular Hydrogen-Atom Transfer

2021 ◽  
Author(s):  
S. Treacy ◽  
X. Zhang ◽  
T. Rovis
Keyword(s):  
Hydrogen Atom ◽  
Functional Groups ◽  
Open Shell ◽  
Hydrogen Atom Transfer ◽  
Atom Transfer ◽  
Stable Carbon ◽  
Radical Reactivity ◽  
Recent Advances ◽  
Synthetic Chemist ◽  
Intramolecular Hydrogen

AbstractRecent advances in intramolecular hydrogen-atom transfer (HAT) have demonstrated significant utility in C—H functionalization through highly reactive open-shell intermediates. The intramolecular transposition of radical reactivity from select functional groups to generate more stable carbon-centered radicals often proceeds with high regioselectivity, providing novel bond disconnections at otherwise inert and largely indistinguishable positions. This chapter explores the functional groups capable of intramolecular HAT to generate remote radicals and the transformations currently available to the synthetic chemist.

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