Understanding the Role of Gadoxetic Acid in MRI

2020 ◽  
Vol 16 (5) ◽  
pp. 572-577
Author(s):  
Dorota Rybczynska ◽  
Joanna Pienkowska ◽  
Andrzej Frydrychowski ◽  
Edyta Szurowska ◽  
Anna Jankowska
Keyword(s):  
Computed Tomography ◽  
Contrast Agents ◽  
Large Scale ◽  
Gadoxetic Acid ◽  
Radiological Imaging ◽  
Mr Cholangiography ◽  
Ultrasound Computed Tomography ◽  
Hepatic Lesions ◽  
Parenchymal Enhancement

Background: Radiological imaging methods used at a large scale in the assessment of hepatic lesions include: Ultrasound, computed tomography and magnetic resonance. To further characterize these lesions, specific contrast agents may be added, thus revealing the vascularity of the lesions. Discussion: This review focuses on gadoxetic acid, which is a hepatospecific contrast agent used in MRI. The aim of the review is to briefly explain the mechanism of GA enhancement, describe the enhancement patterns of some benign and malignant hepatic lesions and discuss possible advantages of GA over standard contrast agents. Conclusion: The role of GA in functional MR cholangiography and the idea of accessing liver function by measuring parenchymal enhancement will also be explained.

Adjunctive role of preoperative liver magnetic resonance imaging added to computed tomography among resected pancreatic cancer patients.

2016 ◽  
Vol 34 (4_suppl) ◽  
pp. 207-207
Author(s):  
Hyoung Woo Kim ◽  
Jin-Hyeok Hwang ◽  
Jong-chan Lee ◽  
Kyu-hyun Paik ◽  
Jingu Kang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Hepatic Metastases ◽  
Resonance Imaging ◽  
Liver Mri ◽  
Hepatic Recurrence ◽  
Liver Magnetic Resonance Imaging ◽  
Hepatic Lesions

207 Background: Multi-detector computed tomography using pancreatic protocol (pCT) has been a preferred diagnostic imaging modality before resection of the pancreatic ductal adenocarcinoma (PDAC), because an adjunctive role of liver magnetic resonance imaging (MRI) is still unclear. The current study evaluated whether liver MRI added to pCT can help to select proper surgical candidates, and reduce the risk of early recurrence, eventually result in longer survival in resected PDAC patients. Methods: Among 197 PDAC patients who underwent curative-intended surgery, 167 patients who achieved complete resection with no grossly visible tumor were enrolled retrospectively. All patients had no metastatic lesions on pCT and/or MRI, preoperatively. Among them, 102 patients underwent pCT alone (CT group), and 65 patients liver MRI as well as pCT (MRI group). Results: By adding the liver MRI, hepatic metastases were newly discovered in 3 of 58 patients (5.2%) with no hepatic lesions on pCT and in 17 of 53 patients (32.1%) with indeterminate hepatic lesions on pCT. Among 167 patients who achieved R0/R1 resection, the median overall and disease-free survival were 20.1 vs 29.3 months and 8.5 vs 10.0 months in the CT and the MRI group, respectively (p = 0.011 and = 0.012), during median follow-up of 16.4 months. 80 (78.4%) patients in the CT group and 39 (60.0%) in the MRI group experienced recurrence during follow-up. Cumulative initial hepatic recurrence rate was higher in the CT group than in the MRI group (43.7% vs 18.5% at 1yr and 57.4% vs 26.9% at 2yr, p < 0.001), although the other sites recurrence did not differ in both groups. Conclusions: Liver MRI added to pCT has an incremental value in detecting PDAC hepatic metastases. Furthermore, because PDAC patients who underwent resection after liver MRI as well as pCT expect lower rate of hepatic recurrence and better survival than pCT alone, therefore, liver MRI added to pCT is needed to patients who planned curative resection of PDAC.

The Role of Ultrasound, Computed Tomography and FNAB in the Diagnosis of Pancreatic Mass Lesions - Defining the Indications for FNAB Application

2008 ◽  
Vol 80 (5) ◽  
Author(s):  
Grzegorz Ćwik ◽  
Grzegorz Wallner ◽  
Aleksander Ciechański ◽  
Przemysław Mądro ◽  
Tomasz Skoczylas
Keyword(s):  
Computed Tomography ◽  
Pancreatic Mass ◽  
Ultrasound Computed Tomography ◽  
Mass Lesions

Using the Bosniak classification from the perspective of current clinical guidelines: the role of multiparameter ultrasound

2021 ◽  
Vol 90 (4) ◽  
pp. 47-56
Author(s):  
E.V. Polukhina ◽  
◽  
M.V. Gerasyanova ◽  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Magnetic Resonance ◽  
Clinical Guidelines ◽  
Common Finding ◽  
Resonance Imaging ◽  
Bosniak Classification ◽  
Radiation Imaging ◽  
Ultrasound Computed Tomography

Kidney cystic formations are a common finding during ultrasound, computed tomography and magnetic resonance imaging. Most kidney cysts are benign, however, in 5–7 % of cases, renal cell carcinoma can be represented by a complex cystic formation. The Bosniak classification allows you to determine the risk of a malignant process and, depending on the assignment of the resulting image to a category, plan treatment tactics. The classification was initially based on the characteristics of cysts according to computed tomography data. Other methods of radiation imaging, such as magnetic resonance imaging and ultrasound, are now also used to characterize complex cystic lesions. The article provides data on the assessment of renal cystic formations according to the Bosniak classification according to modern clinical guidelines, including the use of multiparametric ultrasound

scholarly journals Multiple Focal Nodular Hyperplasia and Steatohepatitis: Atypical Imaging Characteristics

2001 ◽  
Vol 15 (2) ◽  
pp. 137-142 ◽  
Author(s):  
Robert P Myers ◽  
Dónal Downey ◽  
Subrata Chakrabarti ◽  
Paul J Marotta
Keyword(s):  
Magnetic Resonance Imaging ◽  
Computed Tomography ◽  
Malignant Melanoma ◽  
Focal Nodular Hyperplasia ◽  
Resonance Imaging ◽  
Benign Condition ◽  
Imaging Characteristics ◽  
Ultrasound Computed Tomography ◽  
Nodular Hyperplasia ◽  
Hepatic Lesions

Focal nodular hyperplasia is a rare, benign condition of the liver. A 28-year-old woman with malignant melanoma, mild liver enzyme abnormalities, steatohepatitis and newly documented hepatic lesions is described. Ultrasound, computed tomography and magnetic resonance imaging suggested only areas of focal fatty sparing but could not eliminate the concern for metastases. A99mtechnetium-labelled sulphur colloid scan, however, revealed areas of increased uptake consistent with multiple focal nodular hyperplasia. This diagnosis was ultimately confirmed with a liver biopsy. The investigation of a patient with a malignancy and expanding hepatic lesions is challenging. This case illustrates the usefulness of the99mtechnetium-labelled sulphur colloid scan in the evaluation of patients with hepatic lesions.

Polymerization-induced self-assembly of large-scale iohexol nanoparticles as contrast agents for X-ray computed tomography imaging

2018 ◽  
Vol 9 (21) ◽  
pp. 2926-2935 ◽  
Author(s):  
Yuxun Ding ◽  
Xinyu Zhang ◽  
Yingjin Xu ◽  
Tangjian Cheng ◽  
Hanlin Ou ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Contrast Agents ◽  
Self Assembly ◽  
Large Scale ◽  
Computed Tomography Imaging ◽  
One Pot ◽  
X Ray ◽  
Tomography Imaging ◽  
Fundamental Research ◽  
X Ray Computed

Fundamental research for CT imaging, in which iohexol nanoparticles (INPs) were synthesised using a one-pot strategy via polymerization-induced self-assembly (PISA).

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