A Mini Review on Surface Enhanced Raman Scattering based Nanoclusters for Sensing and Imaging Applications

2021 ◽  
Vol 17 ◽  
Author(s):  
Rajasekhar Chokkareddy ◽  
Suvardhan Kanchi ◽  
Inamuddin
Keyword(s):  
Raman Scattering ◽  
Water Solubility ◽  
Surface Enhanced Raman Scattering ◽  
Metal Nanoclusters ◽  
Absorption Bands ◽  
Sensing Applications ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Background: The invention of enhanced Raman scattering by adsorbing molecules on nanostructured metal surfaces is a milestone in the development of spectroscopic and analytical techniques. Important experimental and theoretical efforts were geared towards understanding the Surface Enhanced Raman Scattering effect (SERS) and evaluating its significance in a wide range of fields in different types of ultrasensitive sensing applications. Methods: Metal nanoclusters have been widely studied due to their unique structure and individual properties, which place them among single metal atoms and larger nanoparticles. In general, the nanoparticles with a size less than 2 nm is defined as nanoclusters (NCs) and they possess distinct optical properties. In addition, the excited electrons from absorption bands results in the emission of positive luminescence associated to the quantum size effect in which separate energy levels are produced. Results: It is demonstrated that fluorescent based SERS investigations of metal nanoparticles have showed more photostability, high compatibility, and good water solubility, has resulted in high sensitivity, better imaging and sensing experience in the biomedical applications. Conclusion: In the present review, we report recent trends in the synthesis of metal nanoclusters and their applications in biosensing and bio-imaging applications due some benefits including cost-effectiveness, easy synthesis routes and less consumption of sample volumes. Outcomes of this study confirms that SERS based fluorescent nanoclusters could be one of thrust research areas in biochemistry and biomedical engineering.

scholarly journals Surface-Enhanced Raman Scattering-Based Lateral-Flow Immunoassay

Nanomaterials ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 2228
Author(s):  
Boris Khlebtsov ◽  
Nikolai Khlebtsov
Keyword(s):  
Raman Scattering ◽  
Point Of Care ◽  
Surface Enhanced Raman Scattering ◽  
Environmental Safety ◽  
Lateral Flow ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Low Sensitivity

Lateral flow immunoassays (LFIAs) have been developed and used in a wide range of applications, in point-of-care disease diagnoses, environmental safety, and food control. However, in its classical version, it has low sensitivity and can only perform semiquantitative detection, based on colorimetric signals. Over the past decade, surface-enhanced Raman scattering (SERS) tags have been developed in order to decrease the detection limit and enable the quantitative analysis of analytes. Of note, these tags needed new readout systems and signal processing algorithms, while the LFIA design remained unchanged. This review highlights SERS strategies of signal enhancement for LFIAs. The types of labels used, the possible gain in sensitivity from their use, methods of reading and processing the signal, and the prospects for use are discussed.

Surface-Enhanced Raman Scattering: A Technique of Choice for Molecular Detection

2013 ◽  
Vol 754 ◽  
pp. 143-169 ◽  
Author(s):  
Mohammad Kamal Hossain
Keyword(s):  
Raman Scattering ◽  
Cost Effective ◽  
Surface Enhanced Raman Scattering ◽  
Localized Surface Plasmon ◽  
Raman Signal ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Effective Development

Although surface-enhanced Raman scattering (SERS) has crossed its infancy long ago, it is yet to persuade different challenges to make it available in day-to-day applications. SERS is being criticized mainly due to the quality of the SERS analyses that uses substrates to get the giant enhancement for respective Raman signal of the target molecule. Hence, understanding the phenomena behind substrates, cost-effective development and optimization of such substrates for routine analytical purposes and utilization of modern modalities to get the insights out has become a very wide-spreading and interesting area of research. In this piece of work, several key terminologies related to SERS have been presented in brief. Since SERS is a localized surface plasmon resonance (LSPR) mediated signal-enhancing phenomena, it is indispensable to understand the correlation between LSPR excitations originated from substrate and SERS signal originated from molecules. A wide range of SERS-active substrates including scattered nanoaggregates, anisotropic assembly, two-dimensional nanostructure, multi-layered nanostructure of gold nanoparticles and colloidal approach have been used to interpret such correlation between LSPR excitations and SERS characteristics. Few exemplary applications of SERS have been also mentioned followed by typical simulative work how nanoobject behaves at different excitations and polarizations.

Synthesis of porous Au–Ag alloy nanorods with tunable plasmonic properties and intrinsic hotspots for surface-enhanced Raman scattering

CrystEngComm ◽  
2021 ◽  
Author(s):  
Shanlin Ke ◽  
Caixia Kan ◽  
Xingzhong Zhu ◽  
Changshun Wang ◽  
Xiu Wang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Highly Sensitive ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

The tunability of longitudinal plasmonic bands of P-AuAgNRs is realized to cover a wide range of wavelengths. P-AuAgNRs exhibit numerous internal hotspots which favor highly sensitive surface-enhanced Raman scattering detection.

scholarly journals Binary Surfactant–Mediated Tunable Nanotip Growth on Gold Nanoparticles and Applications in Photothermal Catalysis

2021 ◽  
Vol 9 ◽  
Author(s):  
Xiaohu Mi ◽  
Tingting Zhang ◽  
Baobao Zhang ◽  
Min Ji ◽  
Bowen Kang ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Au Nanoparticle ◽  
Plasmonic Nanostructures ◽  
Hexadecyltrimethylammonium Bromide ◽  
Strong Light ◽  
Wide Range ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Plasmonic nanostructures with sharp tips are widely used for optical signal enhancement because of their strong light-confining abilities. These structures have a wide range of potential applications, for example, in sensing, bioimaging, and surface-enhanced Raman scattering. Au nanoparticles, which are important plasmonic materials with high photothermal conversion efficiencies in the visible to near-infrared region, have contributed greatly to the development of photothermal catalysis. However, the existing methods for synthesizing nanostructures with tips need the assistance of poly(vinylpyrrolidone), thiols, or biomolecules. This greatly hinders signal detection because of stubborn residues. Here, we propose an efficient binary surfactant–mediated method for controlling nanotip growth on Au nanoparticle surfaces. This avoids the effects of surfactants and can be used with other Au nanostructures. The Au architecture tip growth process can be controlled well by adjusting the ratio of hexadecyltrimethylammonium bromide to hexadecyltrimethylammonium chloride. This is due to the different levels of attraction between Br−/Cl− and Au3+ ions. The surface-enhanced Raman scattering and catalytic abilities of the synthesized nanoparticles with tips were evaluated by electromagnetic simulation and photothermal catalysis experiments (with 4-nitrothiophenol). The results show good potential for use in surface-enhanced Raman scattering applications. This method provides a new strategy for designing plasmonic photothermal nanostructures for chemical and biological applications.

Graphene-based nanoplatforms for surface-enhanced Raman scattering sensing

The Analyst ◽  
2018 ◽  
Vol 143 (21) ◽  
pp. 5074-5089 ◽  
Author(s):  
Zhuqing Wang ◽  
Shasha Wu ◽  
Lucio Colombi Ciacchi ◽  
Gang Wei
Keyword(s):  
Raman Scattering ◽  
Surface Enhanced Raman Scattering ◽  
Sensing Applications ◽  
Recent Advances ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Sers Sensing

We demonstrate recent advances in the fabrication and SERS sensing applications of graphene-based nanoplatforms.

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