scholarly journals Socio-Behavioral Risk Factors Associated with Cryptosporidiosis in HIV/AIDS Patients Visiting the HIV Referral Clinic at Cape Coast Teaching Hospital, Ghana

2018 ◽  
Vol 12 (1) ◽  
pp. 106-116
Author(s):  
Yeboah K. Opoku ◽  
Johnson N. Boampong ◽  
Irene Ayi ◽  
Godwin Kwakye-Nuako ◽  
Dorcas Obiri-Yeboah ◽  
...  
Keyword(s):  
Risk Factors ◽  
Drinking Water ◽  
Risk Factor ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
Cape Coast ◽  
Aids Patients ◽  
Factors Associated ◽  
Enteric Protozoan ◽  
Hiv Aids

Objective:To identify the socio-behavioral risk factors associated with cryptosporidiosis among HIV/AIDS patients with chronic diarrhea symptoms visiting the HIV referral clinic at Cape Coast Teaching Hospital, Ghana.Methods:A cross-sectional study was conducted among 50 HIV/AIDS patients with recurrent diarrhea. Questionnaires were administered to collect social and behavioral risk factors associated withCryptosporidiumand other opportunistic protozoan parasitic infections in HIV patients. Stool samples were collected for the diagnosis of enteric protozoan pathogens using modified Ziehl-Neelsen and acid-fast staining methods. CD4+cells counts of study subjects were obtained from patients clinical records. The data obtained were analyzed using Pearson chi-square and multivariate-adjusted statistics tool on SPSS 16 for Windows.Results:Twenty-seven (54%) of the subjects were infected with enteric protozoan pathogens. The prevalences ofCryptosporidium,CyclosporaandMicrosporidiuminfections were 46%, 32% and 16%, respectively.Cryptosporidiuminfection was significantly associated with drinking water (×2=13.528, p<0.001),Cyclosporawas associated with the type of drinking water (×2=14.931, p<0.001) and toilet facilities used by the study subjects (×2=12.463, p<0.01), whilesMicrosporidiuminfection was associated with hand washing behavior (×2=12.463, p<0.01). Enteric protozoans were frequently encountered among subjects with CD4+ T-cell count <200 cells/mm3. However, coinfection ofCyclospora spp&Cryptosporidiumspp was not observed in CD4+cell count <200 and >500 cells/mm3.Multivariate analysis showed that the risk factor forCryptosporidiuminfection among HIV/AIDS patients was the source of drinking water (pipe borne water 76.2% prevalence: sachet water 25%; OR=0.10, 95%CI: 0.03-0.39, p<0.001).Conclusion:We report the risk factor for exposure ofCryptosporidiuminfection among HIV/AIDS patients for the first time in Ghana. The contamination of drinking water by protozoan parasites should be a public health concern. These results provide the stepping block to understand the transmission dynamics ofCryptosporidiumand other opportunistic pathogens in HIV/AIDS infected patients in Ghana.

scholarly journals Description Analysis of Human Behavior that Causes the Emergence of HIV/AIDS Infectious Diseases in Surabaya

2010 ◽  
Vol 1 (2) ◽  
pp. 93
Author(s):  
Yayuk Susilawati ◽  
Nasronudin Nasronudin ◽  
Atika Atika
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Human Behavior ◽  
Clinical Symptoms ◽  
Perinatal Period ◽  
Sexual Contact ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
And Bisexual ◽  
Hiv Aids

HIV virus is transmitted to other individuals particularly through sexual contact with infected individuals, narcotic abuse using shared infected needle, maternal-fetal transmission in perinatal period, either during pregnancy, labor, and breastfeeding, or through infected blood donor. The diagnosis of HIV/AIDS infection is established using laboratory examination with the indication of clinical symptoms or high risk behavior. This descriptive study was intended to describe human behaviors that cause the occurrence of HIV/AIDS in Surabaya. To find the description of the disease, the percentage of total HIV/AIDS patients according to behavioral risk factors was estimated. Total patients in 9 hospitals at each risk factor were divided with total patients in those hospital, multiplied with 100. The description of the disease according to behavioral risk factors in Surabaya is as follows: total patients between January and December 2005 was 382 individuals; 204 due to sexual contact (53.40%), 161 due to injected drug use (IDU) (42.15%), 6 perinatal cases (1.57%) and 11 with unknown causes (2.88%). From risk factor sexual relationship behavior as many as 204 people, respectively heterosexual 174 people (85.29%), homosexual 17 people (8.33%) and bisexual 13 people (6.37%). Further analytical studies are needed to analyze correlation between human behavior and the occurrence of HIV/AIDS in Surabaya.

Factors associated to first line antiretroviral therapy (ART) failure among HIV/AIDS patients at Sanglah Hospital, Bali

2017 ◽  
pp. 4
Author(s):  
Cok Istri Sri Dharma Astiti ◽  
A.A Sagung Sawitri ◽  
Tuti Parwati
Keyword(s):  
Risk Factors ◽  
Treatment Failure ◽  
Clinical Stage ◽  
Hiv And Aids ◽  
First Line ◽  
Aids Patients ◽  
Factors Associated ◽  
Art Initiation ◽  
Risk Of Treatment ◽  
Hiv Aids

Background and purpose: The incidence of first line ART failure is increasing in the South East Asia region. The main referral hospital in Bali has recorded an increased use of second line ART due to the first line ART failure. This study aims to explore risk factors associated to first line ART failure.Methods: A case control study was conducted among people living with HIV and AIDS at Sanglah Hospital Denpasar who started first line ART between 2004 and 2013. Cases were those who diagnosed as having clinical treatment failure and still on treatment in 2015. Controls were those with no treatment failure. Sex and year of ART initiation were matched between case and control. Data were obtained from medical records that include initial regiments, HIV mode of transmission, the WHO HIV clinical stage, CD4 count, opportunistic infections, body mass index, hemoglobin level, and drug substitution at the beginning and during treatment. Risk factors were analysed using logistic regression.Results: Out of 68 HIV/AIDS patients with clinical ART failure, 72.1% were confirmed with immunological and 36.8% were confirmed with virological failure. Median time before treatment failure was 3.5 years. Factors associated to ART failure were HIV clinical stage IV with (AOR=3.43; 95%CI=1.65-7.13) and being widow/widower (AOR=4.85; 95%CI=1.52-15.53). Patients with TB co-infection have a lower risk for treatment failure due to early diagnosis and treatment through TB-HIV program with (AOR=0.32; 95%CI=0.14-0.70).Conclusions: Higher HIV clinical stage at ART initiation increases the risk of treatment failure. HIV-TB co-infection indirectly reduces the risk of treatment failure.

REPRINT OF: The Behavioral Risk Factor Surveys: I. State-Specific Prevalence Estimates of Behavioral Risk Factors

2020 ◽  
Vol 59 (6) ◽  
pp. 779-786
Author(s):  
James S. Marks ◽  
Gary C. Hogelin ◽  
Eileen M. Gentry ◽  
Jack T. Jones ◽  
Karen L. Gaines ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
Behavioral Risk Factor ◽  
Prevalence Estimates

scholarly journals Factors associated with chronic kidney disease in HIV+ patients in Albert Luthuli Municipality of South Africa

2020 ◽  
Author(s):  
PEPUKAI BENGURA ◽  
Principal Ndlovu ◽  
Mulalo Annah Managa
Keyword(s):  
Risk Factors ◽  
South Africa ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Antiretroviral Treatment ◽  
P Value ◽  
Aids Patients ◽  
Factors Associated ◽  
Research Findings ◽  
Hiv Aids

Abstract Background: Current research indicates that chronic kidney disease is a global problem which poses a major health threat to people of poor countries who have HIV/AIDS and are on antiretroviral treatment. In this study, the prevalence of chronic kidney disease and the factors associated with it were investigated among the HIV/AIDS patients in a rural community of South Africa. Methods: A cohort of HIV+ terminal ill patients was retrospectively followed from 2010 to 2017 until chronic kidney disease was diagnosed or until the end of the observation period at two hospitals (Carolina and Embhuleni). Patient information was obtained from the routine hospitals’ records, and the data were analysed using logistic regression and survival analysis (Kaplan-Meier hazard functions and ratios, and log-rank tests) methods. Results: Out of a random sample of 357 HIV/AIDS patients, 53 patients (14.85%) had chronic kidney disease. The factors associated with chronic kidney disease were: Gender (p-value<0.0024); Age (p-value<0.0420); Baseline creatinine (p-value<0.0116); Baseline alanine transaminase (p-value<0.0111); Treatment regimen 1 (p-value<0.0001); ART adherence (poor, fair, good) (p-value<0.0005); Hospital (p-value<0.0001); and Lost to follow-up (ye, no) (p-value<0.0069). Discussion: Whilst antiretroviral treatment is associated with some improvement in virology and immunology in HIV-infected patients, research is still needed for the assessment of the impact of ART and other risk factors on renal function in marginalised communities in Africa. Conclusion: The research findings on HIV+ patients in Albert Luthuli Municipality concurred with several previous research findings on risk factors to CKD. The expected action to alleviate the health threat due to CKD in South Africa is to educate the nation on prevention, early detection and on the management of the disease. The study established diverse baseline statistics against which future research may be based.

scholarly journals Prevalence of Physiological, Pathological and Behavioral Risk Factors in Patients Treated with Antidiabetic Sulfonylureas

2015 ◽  
Vol 61 (4) ◽  
pp. 342-344
Author(s):  
Confederat Luminita ◽  
Stefan Roxana ◽  
Constantin Sandra ◽  
Hăncianu Monica ◽  
Profire Lenuta
Keyword(s):  
Risk Factors ◽  
Medical Center ◽  
Public Health Problem ◽  
Diabetic Patients ◽  
Behavioral Risk Factors ◽  
Behavioral Risk ◽  
Important Public Health Problem ◽  
Obesity Class ◽  
Factors Associated ◽  
High Prevalence

AbstractDiabetes mellitus is an important public health problem because of its increased incidence and its devastating complications. In addition to this, it was observed an increase in prevalence for diabetes risk factors. The aim of this study was to evaluate the frequency of the pathophysiological and behavioral risk factors among patients treated with oral hypoglycemic sulfonylureas.Material and methods: It were analyzed the observation sheets of 200 patients ambulatory treated at the “Providența” Medical Center.Results and discussions: Most of the patients were aged over 65 years, being 48.5% women and 51.5% men. The obesity was the most frequent (88%) risk factor in patients; the majority of them were included in the “overweight” and “first- degree obesity” class (72%). Regarding associated comorbidities, hypertension was found in 77% of cases, followed by dyslipidemia. In terms of physiological and behavioral aspects, age and alcohol consumption were predominant.Conclusions: A significant percentage of diabetic patients treated with hypoglycemic sulfonylureas present a high prevalence of the risk factors and even two or three factors associated.

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