scholarly journals INFLUENCE OF TYPE 2 DIABETES MELLITUS ON THE PREVENTION AND TREATMENT OF PROSTHETIC STOMATITIS

2021 ◽  
Vol 77 (3) ◽  
pp. 14-23
Author(s):  
Robert Badalov ◽  
Irina Chernyavskaya
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Oral Cavity ◽  
Oral Mucosa ◽  
Dental Treatment ◽  
Statistical Significance ◽  
The State ◽  
Local Immunity

Purpose: to study the effect of type 2 diabetes mellitus on the state of the mucous membrane and tissues of the oral cavity to optimize the prevention and increase the effectiveness of dentition defects complex treatment in this contingent of patients. Materials and methods. We examined 112 patients with type 2 diabetes mellitus aged 35 to 64 years, who were further divided into three groups. The state of the oral mucosa, morphological changes, local immunity, lysozyme were determined. The work used morphological, microscopic methods, enzyme immunoassay and spectrophotometry. To test the statistical significance of intergroup differences, the nonparametric Mann- Whitney test was used. Results. Oral use in patients with diabetes mellitus type 2, applications of 1% Clotrimazole cream and Echinacea Compositum S had a positive preventive and therapeutic effect, which was accompanied by an increase in capillary resistance, a decrease in the degree of migration of leukocytes, an increase in the functional activity of immune system cells and an increase in the level of regenerative processes. In patients with defects in the dentition against the background of type 2 diabetes mellitus, violations of the oral cavity local immunity were revealed, characterized by a significant increase in the S-IgA content and a decrease in lysozyme.Orthopedic treatment with partial removable denturesled to a significant decrease in the concentration of S-IgA and an increase in the bactericidal activity of saliva due to increased lysozyme synthesis. It was concluded that type 2 diabetes mellitus affects the state of the oral mucosa, which must be taken into account when providing orthopedic and dental treatment.

scholarly journals PREVALÊNCIA DE DIABETES MELLITUS TIPO 2 EM SUBPOPULAÇÃO DO ESTADO DE SERGIPE

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Ana Thaís Fontes Santos ◽  
Elizabete Teixeira Da Silva ◽  
Mariana Costa Larré ◽  
Ana Dorcas De Melo Inagaki ◽  
José Rodrigo Santos Silva ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Statistical Significance ◽  
The State ◽  
Categorical Variables ◽  
P Value ◽  
Cross Sectional ◽  
Foot Injury

Objetivo: Detectar a prevalência do Diabetes Mellitus tipo 2, ocorrência de fatores de risco e complicações em uma subpopulação do estado de Sergipe. Metodologia: Trata-se de um estudo transversal, descritivo e quantitativo, realizado por meio de formulário contemplando dados sociodemográficos e clínicos do paciente. A amostra foi obtida por conveniência, com 307 pacientes. As variáveis categóricas foram avaliadas pelo Teste Qui-Quadrado e Exato de Fisher e adotada significância estatística para p-valor de 5% (0,05). Resultados: A prevalência de diabetes foi 38,1%. O fator de risco que apresentou associação foi à hipertensão. Lesão nos pés esteve presente em 69,3%. Conclusão: As condições socioeconômicas e educacionais da população são fatores dificultadores para promoção da saúde e prevenção do diabetes e suas complicações.Descritores: Diabetes Mellitus; Epidemiologia; Complicações do Diabetes; Doença Crônica; Prevalência.PREVALENCE OF TYPE 2 DIABETES MELLITUS IN SUBPOPULATION OF THE STATE OF SERGIPEObjective: To detect the prevalence of Type 2 Diabetes Mellitus, the occurrence of risk factors and complications in a subpopulation of the state of Sergipe. Methodology: This is a cross-sectional, descriptive and quantitative study, carried out by means of a form containing sociodemographic and clinical data of the patient. The sample was obtained for convenience, with 307 patients. Categorical variables were assessed by Chi-square and Fisher’s exact test and adopted a statistical significance for p-value of 5% (0.05). Results: The prevalence of diabetes was 38.1%. The risk factor that presented association was hypertension. Foot injury was present in 69.3%. Conclusion: The socioeconomic and educational conditions of the population are factors that make it difficult to promote health and prevent diabetes and its complications.Descriptors: Diabetes Mellitus; Epidemiology; Diabetes Complications; Chronic Disease; Prevalence.PREVALENCIA DE DIABETES MELLITUS TIPO 2 EN LA SUBPOBLACIÓN DEL ESTADO DE SERGIPEObjetivo: Detectar la prevalencia de la Diabetes Mellitus tipo 2, ocurrencia de factores de riesgo y complicaciones en una subpoblación del estado de Sergipe. Metodología: Se trata de un estudio transversal, descriptivo y cuantitativo, realizado por medio de formulario contemplando datos sociodemográficos y clínicos del paciente. La muestra fue obtenida por conveniencia, con 307 pacientes. Las variables categóricas fueron evaluadas por el Test Qui-cuadrado y Exacto de Fisher y se adoptó significancia estadística para p-valor del 5% (0,05). Resultados: La prevalencia de la diabetes fue del 38,1%. El factor de riesgo que presentó asociación fue a la hipertensión. La lesión en los pies estuvo presente en el 69,3%. Conclusión: Las condiciones socioeconómicas y educativas de la población son factores dificultadores para la promoción de la salud y prevención de la diabetes y sus complicaciones.Descriptores: Diabetes Mellitus; Epidemiología; Complicaciones de la Diabetes ; Enfermedad Crónica; Prevalencia.

scholarly journals The Effect ofTinospora crispaon Serum Glucose and Insulin Levels in Patients with Type 2 Diabetes Mellitus

2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
Theerawut Klangjareonchai ◽  
Chulaporn Roongpisuthipong
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Healthy Subjects ◽  
Statistical Significance ◽  
Area Under The Curve ◽  
Serum Glucose ◽  
Dry Powder ◽  
Insulin Levels

Objective. To determine the effects ofTinospora crispaon serum glucose and insulin levels in healthy subjects and patients with type 2 diabetes mellitus.Method. Serum from 10 healthy subjects and 10 diabetic participants, who had fasted overnight, were obtained every 30–60 minutes during the 3 hours of continued fasting and during the 3 hours after ingestion of 75 g of glucose with or without ingestion of 125 or 250 g ofTinospora crispadry powder capsule. Glucose and Insulin levels were analyzed and the areas under the curve for mean serum glucose and insulin levels were calculated.Result. The areas under the curve of mean serum glucose and insulin levels in both healthy and diabetic participants were not significantly different between with or withoutTinospora crispadry powder capsule. In diabetic participants the area under the curve of glucose was slightly lesser when 250 mg ofTinospora crispawas ingested, but not reaching statistical significance (478 and 444 mg min/ml, resp.,P=0.57).Conclusion. The results suggest thatTinospora crispaingestion cannot affect serum glucose and insulin levels in healthy subjects or patients with type 2 diabetes mellitus.

scholarly journals C-REACTIVE PROTEIN IN DIABETIC PATIENTS BEFORE GASTRIC BYPASS AS A POSSIBLE MARKER FOR POSTOPERATIVE COMPLICATION

2015 ◽  
Vol 28 (suppl 1) ◽  
pp. 11-14 ◽  
Author(s):  
Daniel C. LINS ◽  
Josemberg M. CAMPOS ◽  
Patrícia S. de PAULA ◽  
Manoel GALVÃO-NETO ◽  
Eduardo PACHU ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Gastric Bypass ◽  
Type 2 Diabetes Mellitus ◽  
Postoperative Complications ◽  
Statistical Significance ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Inflammatory State

Background : Obesity and type 2 diabetes mellitus are associated to inflammatory state, which can be set off by the adipose tissue, once it is a metabolically active organ that can cause a chronic mild inflammatory state. Aim : To evaluate the correlation between preoperative C-reactive protein and postoperative complications risk in obese patients (grades II and III) after Roux-en-Y gastric bypass, with and without type 2 diabetes mellitus. Methods : Between 2008 and 2013 were analysed 209 patients (107 with diabetes), presenting body mass index >40 kg/m2or >35 kg/m2with comorbidities. During the postoperative period, two groups were evaluated: with and without complications. Preoperative ultra-sensitive C-reactive protein was measured by immunonephelometry method. Results : Complications occurred in seven patients (pulmonary thromboembolism, fistula, two cases of suture leak, pancreatitis, evisceration and upper digestive hemorrhage). No statistical significance was found regarding lipid profile and C-reactive protein between patients with and without type 2 diabetes mellitus. When compared to each other, both groups (with and without complications) presented with statistical significance regarding C-reactive protein level (7,2 mg/dl vs 3,7 mg/dl, p=0,016) and had similar weight loss percentage after 3, 6 and 12 months follow-up. Conclusions : Preoperative C-reactive protein serum level was higher in the group which presented complications after Roux-en-Y gastric bypass when compared to the group without postoperative complications.

scholarly journals The Association of Uric Acid Calculi with Obesity, Prediabetes, Type 2 Diabetes Mellitus, and Hypertension

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Fang-Yeh Chu ◽  
Chih-Chun Chang ◽  
Pin-Hao Huang ◽  
Yi-Ning Lin ◽  
Po-Wen Ku ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Urinary Tract Infection ◽  
Type 2 Diabetes Mellitus ◽  
Uric Acid ◽  
Surgical Management ◽  
Surgical Intervention ◽  
Statistical Significance ◽  
Urinary Calculi

Objectives.To disclose the link between the composition of urolithiasis, especially that of uric acid calculi, and obesity, prediabetes, type 2 diabetes mellitus, and hypertension.Materials and Methods.Patients who had urinary calculi and underwent surgical treatment were registered in the study. The composition of urinary calculi was analyzed and correlated with clinical features and biomedical profiles of the patients before surgical intervention.Results.A total of 666 patients with urolithiasis who underwent surgical management were registered and analyzed. In those who had uric acid calculi, there was a significant association with prediabetic (OR: 20.11, 95% CI: 7.40–54.63,P<0.001) and diabetic states (OR: 11.55, 95% CI: 4.41–29.97,P<0.001). It also seemed that uric acid calculi were related to obesity but there was no statistical significance (OR: 2.45, 95% CI: 0.91–6.62,P=0.078). There was no association of uric acid calculi with hypertension (OR: 1.08, 95% CI: 0.54–2.17,P=0.822) and concurrent urinary tract infection (OR: 0.93, 95% CI: 0.44–1.96,P=0.841).Conclusion.There was a remarkable association of uric acid calculi with prediabetic and diabetic states. The uric acid calculi were also seemingly associated with obesity in patients with urolithiasis undergoing surgical management.

scholarly journals Poor Adherence to Common Recommendations and Associated Factors among Outpatients with Type 2 Diabetes Mellitus in a Police Hospital of Ethiopia

2021 ◽  
Vol 9 (01) ◽  
pp. e8-e14
Author(s):  
Tariku Shimels ◽  
Melesse Abebaw ◽  
Gebremedhin Beedemariam Gebretekle
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Statistical Significance ◽  
Poor Adherence ◽  
Semistructured Interview ◽  
Good Adherence ◽  
Adherence To Medication ◽  
Adequate Knowledge

Abstract Introduction Poor adherence to medication and healthy lifestyle managements, such as diet and regular exercise, remains to be a challenge for patients with type 2 diabetes mellitus. The objective of this study was to assess the pattern of adherence to common recommendations, reasons, and factors associated with poor overall adherence among outpatients with type 2 diabetes mellitus in a police hospital of Ethiopia. Method A facility-based cross-sectional study was done between 15 October 2016 and 15 January 2017. Systematic random sampling method was applied to recruit participants. A semistructured interview guide with an observation checklist was used to collect data. SPSS v.20.0 was used in the analysis. Results Out of 361 participants, over half (56.5%) participants were male and 235 (65.1%) participants were military. Nearly half (49%) of the participants were on oral combination therapy. Only 194 (53.7%) of the patients showed good adherence for diet. Half (50.1%) of the respondents had poor adherence to all recommendations. Reasons for poor adherence included lack of adequate knowledge (68.9%) for diet, carelessness (37.8%) for exercise, and lack of adequate knowledge (34.8%) followed by carelessness (28.3%) and forgetfulness (19.6%) for medication. Intake of herbal medicines doubled the likelihood of good adherence. Conclusion Adherence of patients to diet was found to be suboptimal. Lack of adequate knowledge, carelessness, and forgetfulness were among the reasons mentioned. Only use of herbal medicine showed statistical significance with adherence. Patient education on dietary practice is required in the study setting.

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