scholarly journals Experience in the use of modern H-SIL diagnostic methods in the screening of cervical cancer on the example of the Rostov region

2019 ◽  
Vol 10 (1) ◽  
pp. 28-34
Author(s):  
Tatiana A. Dimitriadi ◽  
Dmitry V. Burtsev ◽  
Elena A. Dzhenkova ◽  
Alexander F. Mikhelson ◽  
Elizaveta Yu. Lebedenko
Keyword(s):  
Cervical Cancer ◽  
Screening Program ◽  
Video Recording ◽  
Diagnostic Methods ◽  
Pap Smears ◽  
Rostov Region ◽  
Cancer Screening Program ◽  
Hpv Test ◽  
Cervical Cancer Screening Program ◽  
Liquid Based Cytology

Objective: to evaluate the eff ectiveness of the regional cervical cancer screening program by liquid-based cytology. Materials and Methods: the geography of screening includes 54 medical units of the Rostov region, where patients are taken swabs from the cervix. HPV positive patients with abnormal PAP smears are invited to the Regional cervical pathology center for diagnosis and treatment. Methods. liquid-based cytology, the HPV test RealTime PCR, colposcopy with video recording, biopsy of the cervix by the method of loop excision or electroradiographic conization. Results: From 2014 to 2017, 188 641 cytology tests were performed. Cervical cancer was revealed in 189 women – (0.1 %), H-SIL and ASCH in 566 (0.3 %), 377 ASCUS (0.2 %), L-SIL in 23014 (12.2 %), absence of intracellular lesions or malignancy in 164495 (87.2 %). 2162 HPV-positive women aged 18 to 69 years were invited to the Regional cervical pathology center gynecologist for examination. Treatment by conization (622) and excision (830) of the cervix was performed in 1452 patients, H-SIL and CIS were revealed in 1162 women (78 %). Conclusion: tests such as liquid-based cytology and HPV testing, their optimal multiplicity and sequence allow timely detection and treatment of precancerous cervical epithelium lesions.

PP62 Cost-Effectiveness Of Cervical Cancer Screening In Estonia

2019 ◽  
Vol 35 (S1) ◽  
pp. 49-49
Author(s):  
Triin Võrno ◽  
Kaja-Triin Laisaar ◽  
Terje Raud ◽  
Kai Jõers ◽  
Doris Meigas-Tohver ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cost Effectiveness ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Screening Program ◽  
Pap Test ◽  
Cancer Screening Program ◽  
Hpv Test ◽  
Cervical Cancer Screening Program ◽  
The Cost

IntroductionIn Estonia, organized cervical cancer screening program is targeted at women aged 30–55(59) years and Pap-tests are taken every five years. Since cervical cancer is associated with human papillomavirus (HPV), a number of countries have introduced the HPV-test as the primary method of screening. The objective of this study was to evaluate the cost-effectiveness of organized cervical cancer screening program in Estonia by comparing HPV- and Pap-test based strategies.MethodsFor the cost-effectiveness analysis, a Markov cohort model was developed. The model was used to estimate costs and quality-adjusted life-years (QALYs) of eight screening strategies, varying the primary screening test and triage scenarios, upper age limit of screening, and testing interval. Incremental cost-effectiveness ratios (ICERs) were calculated in comparison to current screening practice as well as to the next best option. Sensitivity analysis was performed by varying one or more similar parameter(s) at a time, while holding others at their base case value. The analysis was performed from the healthcare payer perspective adopting a five percent annual discount rate for both costs and utilities.ResultsIn the base-case scenario, ICER for HPV-test based strategies in comparison to the current screening practice was estimated at EUR 8,596–9,786 per QALY. For alternative Pap-test based strategies ICER was estimated at EUR 2,332–2,425 per QALY. In comparison to the next best option, HPV-test based strategies were dominated by Pap-test based strategies. At the cost-effectiveness threshold of EUR 10,000 per QALY Pap-testing every three years would be the cost-effective strategy for women participating in the screening program from age 30 to 63 (ICER being EUR 3,112 per QALY).ConclusionsDecreasing Pap-test based screening interval or changing to HPV-test based screening can both improve the effectiveness of cervical cancer screening program in Estonia, but based on the current cost-effectiveness study Pap-test based screening every three years should be preferred.

scholarly journals CERVICAL CANCER SCREENING PROGRAM WITH PRIMARY DNA-HPV TEST STARTED IN 2017 IN BRAZILIAN CITY: RESULTS AFTER 18 MONTHS

2019 ◽  
Author(s):  
Julio Teixeira ◽  
Michelle Garcia Discacciati ◽  
Denise da Rocha Pitta Lima de Moraes ◽  
Diama Vale ◽  
Tulio Tomass Couto ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Screening Program ◽  
Cancer Screening Program ◽  
Hpv Test ◽  
Cervical Cancer Screening Program

Frequency of biopsies (BX) and colposcopy (CP) of intraepitelial lesions (IL) in the cervical cancer screening program (CCSP)

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 11000-11000
Author(s):  
S. Holgado ◽  
M. Sanchez Segura ◽  
J. J. Zarba ◽  
C. Monroy ◽  
C. Lorente ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Screening Program ◽  
Public Health Problem ◽  
Pap Smears ◽  
Main Concern ◽  
Screening Programs ◽  
Cancer Screening Program ◽  
Cervical Cancer Screening Program ◽  
Pathology Reports ◽  
In The Beginning

11000 Background: Cervical cancer is a public health problem in developing countries that can be prevent by screening programs. The loss of patients with PAP smears with IL is one of the main concern in the CCSP. The objectives of this study were establish the frequency of IL in the CCSP of Tucumán and determine the frequency of BX and CP in patients with IL within the program. Methods: Data was taken from the clinic-epidemiological charts of CCSP, and pathology reports of 29,169 cytologies (CX) done in women entered in CCSP of Tucumán between 1997 and 2004 The PAP smears were done and informed following Bethesda system and centralized in Hospital Centro de Salud: Zenón Santillán of Tucumán. Results: 2% of the CX were IL. In the beginning of program in 1997 in HSIL and LSIL a BX was performed in 22% and 18% of patients respectively and in 2004 BX was performed in 61% and 25% respectively. There were no data of CP before 2001 but in 2001 a CP was performed in HSIL and LSIL in 21% and 9% and in 2004 CP was performed in 43% and 14% respectively. Conclusion: The percentage of BX and CP performed in IL patients included in the CCSP, increased in the last year of program achieving a 60% and 43% in HSIL which is quite acceptable in a developing country. No significant financial relationships to disclose.

The Quality of Pap Smears from the Brazilian Cervical Cancer Screening Program According to the Human Development Index

2019 ◽  
Vol 13 (3) ◽  
pp. 299-308
Author(s):  
Ricardo Filipe Alves Costa ◽  
Adhemar Longatto-Filho ◽  
Fabiana de Lima Vazquez ◽  
Céline Pinheiro ◽  
Luiz Carlos Zeferino ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Human Development ◽  
Cervical Cancer Screening ◽  
Human Development Index ◽  
Screening Program ◽  
Pap Smears ◽  
Cancer Screening Program ◽  
Cervical Cancer Screening Program
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