scholarly journals Bacterias anaerobias del suelo responsables de la muerte súbita bovina en sabanas tropicales: investigaciones realizadas en Colombia

2008 ◽  
Vol 9 (1) ◽  
pp. 102
Author(s):  
Diego Ortiz ◽  
Luis Carlos Villamil
Keyword(s):  
Sudden Death ◽  
Clostridium Botulinum ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Clostridium Tetani ◽  
Cattle Feeding ◽  
Type C ◽  
Clinical Signs And Symptoms ◽  
Clostridium Chauvoei ◽  
Alternative Solutions

<p>El estudio de las clostridiosis en Colombia debe ser una prioridad para nuestras autoridades sanitarias debido al impacto sanitario que causan estas bacterias en la salud animal. Así mismo, la agudeza de los signos y síntomas clínicos de estas patologías, y el hecho que afectan animales en buenas condiciones de carne, hacen que tengan fuerte impacto económico. Se presenta una revisión de las principales investigaciones realizadas sobre clostridiosis en los últimos años, algunas publicadas en literatura científica y otras en literatura gris. Se hace énfasis en la muerte súbita bovina, condición que incluye varias patologías entre las que se destacan el botulismo bovino producido por las neurotoxinas tipo C y D de <em>Clostridium botulinum</em>, el carbón sintomático (pierna negra) causado por <em>Clostridium chauvoei </em>y en menor proporción el tétanos, causado por el <em>Clostridium tetani</em>. Se reportan algunos avances en la estandarización de metodologías de diagnóstico en laboratorio y en campo, lo mismo que resultados de estudios epidemiológicos desarrollados en zonas afectadas por estas enfermedades. Finalmente, se presenta una visión prospectiva sobre la investigación en los clostridios y las clostridiosis, lo mismo que algunas propuestas de solución a la problemática discutida.</p><p><strong> </strong></p><p><strong>Anaerobic soil bacteria causing sudden death in cattle feeding on tropical savannahs: research in Colombia </strong></p><p>The study of the clostridiosis in Colombia must be a priority for sanitary authorities due to the sanitary and economic impact caused by these bacteria. Disease clinical signs and symptoms, and effect on animals in good meat condition suppose a high financial impact. This article reviews major research in clostridiosis in recent years, published in scientific and gray literature. Emphasis is made on bovine sudden death, which includes a number of diseases among them botulism produced by neurotoxins type C and D of <em>Clostridium botulinum</em>; black leg caused by <em>Clostridium chauvoei </em>and to a lesser extent tetanus, caused by <em>Clostridium tetani</em>. Some progress in standardization of laboratory and field methodologies is reported, as well epidemiology in areas affected by these diseases. We conclude with a prospective proposal of research in clostridia and clostridiosis, as well as some ideas on alternative solutions to the problems discussed. </p>

scholarly journals Black Quarter (BQ) Disease in Cattle and Diagnosis of BQ Septicaemia Based on Gross Lesions and Microscopic Examination

1970 ◽  
Vol 25 (1) ◽  
pp. 13-16 ◽  
Author(s):  
Mahmuda Sultana ◽  
Abdul Ahad ◽  
Paritosh Kumar Biswas ◽  
M Ashiqur Rahman ◽  
Himel Barua
Keyword(s):  
Clinical Symptoms ◽  
Body Condition Score ◽  
Demographic Variable ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Body Part ◽  
Condition Score ◽  
Acute Infectious Disease ◽  
Clinical Signs And Symptoms ◽  
Clostridium Chauvoei

Black quarter (BQ) is an acute, infectious disease caused by Clostridium chauvoei - a Gram-positive, anaerobic organism. This disease is characterized by inflammation with gaseous oedema of skeletal muscle and severe toxaemia. This study was done in Upazilla Veterinary Hospital at Raozan in Chittagong from June to August 2006. During the study period, 25 cases of BQ in cattle were found in eight Unions. Among them the highest (32%) proportion of BQ was found in Raozan Union. Frequency of BQ according to demographic variable was: age incidence of >12 month (60%), male (60%), breed of Red Chittagong (44%), body condition score (BCS) of BCS-2 (88%), and affected body part involving hind quarter muscle (35%). Death was observed with 73% cases. In case of animals that were suffered from BQ, septicaemia developed after 12 h of onset of clinical signs and symptoms. Treatment was ineffective in advanced septicaemic stage. Antibiotic therapy was found to be effective when administered within 12 h of the clinical symptoms. Keywords: Black quarter; Clostridium chauvoei; Demographic variable; Septicaemia; Antibiotic therapyDOI: http://dx.doi.org/10.3329/bjm.v25i1.4848 Bangladesh J Microbiol, Volume 25, Number 1, June 2008, pp 13-16

Kawasaki disease—sudden death as the first presenting symptom

1992 ◽  
Vol 2 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Louis Tsun-cheung Chow ◽  
Wing-hing Chow ◽  
Christopher Chun-hing Tse ◽  
Eric Hon-man Wong ◽  
Koon-sang Wong ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Sudden Death ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Underlying Disease ◽  
Postmortem Examination ◽  
Arterial Aneurysm ◽  
True Nature ◽  
Clinical Signs And Symptoms ◽  
High Index Of Suspicion

SummaryTwo patients are described with sudden death as the first presenting symptom of Kawasaki disease. The first patient died of cardiac tamponade as a result of rupture of a coronary arterial aneurysm at the age of three months and nineteen days. The second patient, one and half years old, developed acute myocardial infarction secondary to coronary arterial aneurysm and thrombosis. The true nature of their underlying disease was realized only after postmortem examination. Their clinical signs and symptoms of Kawasaki disease might be so mild as to escape recognition. A high index of suspicion should be exercised by the clinician in order not to miss this condition, especially in places where Kawasaki disease is uncommon.

High level of oxysterols in neonatal cholestasis: a pitfall in analysis of biochemical markers for Niemann-Pick type C disease

2016 ◽  
Vol 54 (7) ◽  
Author(s):  
Giulia Polo ◽  
Alessandro Burlina ◽  
Francesca Furlan ◽  
Thilini Kolamunnage ◽  
Mara Cananzi ◽  
...  
Keyword(s):  
Clinical Signs ◽  
Gene Mutations ◽  
Signs And Symptoms ◽  
Niemann Pick Disease ◽  
Liquid Chromatography Tandem Mass ◽  
Type C ◽  
Clinical Signs And Symptoms ◽  
Niemann Pick ◽  
High Level ◽  
Negative Controls

AbstractNiemann-Pick disease type C (NPC) is a rare lipid storage disorder characterized by progressive neurological deterioration. Diagnosing NPC is challenging as clinical signs and symptoms are variable and non-specific. Two oxysterols, cholestane-3β,5α,6β-triol (triol) and 7-ketocholesterol (7KC), have been proposed as biomarkers for aiding diagnosis of NPC. This study evaluated the use of triol and 7KC as biomarkers in cholestatic neonates with suspected NPC.Plasma triol and 7KC were analysed as dimethylglycine esters using an liquid chromatography – tandem mass spectrometry (LC-MS/MS) assay in selected neonates with severe cholestasis and suspected NPC (n=7), adults with cholestasis (n=15), patients with confirmed NPC (positive controls; n=11 [one child and 10 adults]), healthy subjects (negative controls; n=40 [20 children and 20 adults]), and cholestatic adults (comparative reference; n=15). The LC-MS/MS method was subjected to a number of tests for accuracy and consistency.Triol and 7KC levels were substantially and significantly increased in NPC positive patients compared with healthy controls (p<0.001). However, positive results (markedly increased levels of both oxysterols) were identified in 6/7 (86%) neonates with cholestasis. Genetic testing confirmed NPC only in one neonate who had increased triol and 7KC, and increased oxysterol levels among neonates with no identified NPC gene mutations were considered likely due to biliary atresia (BA).While the potential of oxysterols as NPC biomarkers has been well evaluated in older patient populations (without cholestasis), our data suggest that cholestasis might represent a pitfall in oxysterol measurements intended to aid diagnosis of NPC in affected patients.

scholarly journals Dementia and Major Neurocognitive Disorders: Some Lessons Learned One Century after the first Alois Alzheimer’s Clinical Notes

Geriatrics ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 5
Author(s):  
Donatella Rita Petretto ◽  
Gian Pietro Carrogu ◽  
Luca Gaviano ◽  
Lorenzo Pili ◽  
Roberto Pili
Keyword(s):  
Young Woman ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Neurocognitive Disorders ◽  
Lessons Learned ◽  
Alzheimer Dementia ◽  
Clinical Notes ◽  
Alois Alzheimer ◽  
Clinical Signs And Symptoms

Over 100 years ago, Alois Alzheimer presented the clinical signs and symptoms of what has been later called “Alzheimer Dementia” in a young woman whose name was Augustine Deter [...]

scholarly journals Correction to: Levoketoconazole improves clinical signs and symptoms and patient-reported outcomes in patients with Cushing’s syndrome

Pituitary ◽  
2020 ◽  
Author(s):  
Eliza B. Geer ◽  
Roberto Salvatori ◽  
Atanaska Elenkova ◽  
Maria Fleseriu ◽  
Rosario Pivonello ◽  
...  
Keyword(s):  
Cushing’S Syndrome ◽  
Patient Reported Outcomes ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Cushing's Syndrome ◽  
Original Version ◽  
Patient Reported ◽  
Author Group ◽  
Clinical Signs And Symptoms

The original version of the article unfortunately contained an error in the first name and the surname of one of the authors in the author group. The last author name was incorrectly published as ‘F. Pecori Giraldi’ and the corrected name is ‘Francesca Pecori Giraldi’ (First name: Francesca; Surname: Pecori Giraldi).

scholarly journals A 38-year demographic study of central and peripheral giant cell granulomas of the jaws

2016 ◽  
Vol 15 (2) ◽  
pp. 220-223 ◽  
Author(s):  
Shadi Saghafi ◽  
Reza Zare-Mahmoodabadi ◽  
Narges Ghazi ◽  
Mohammad Zargari
Keyword(s):  
Giant Cell ◽  
Medical Science ◽  
Age Distribution ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Posterior Maxilla ◽  
Frequent Site ◽  
Male Patients ◽  
Clinical Signs And Symptoms ◽  
Anterior Mandible

Objective: The purpose of this study was to retrospectively analyze the demographic characteristics of patients with central giant cell granulomas (CGCGs) and peripheral giant cell granulomas (PGCGs) in Iranian population.Methods: The data were obtained from records of 1019 patients with CGCG and PGCG of the jaws referred to our department between 1972 and 2010. This 38-year retrospective study was based on existing data. Information regarding age distribution, gender, location of the lesion and clinical signs and symptoms was documented. Results: A total of 1019 patients were affected GCGLs including 435 CGCGs and 584 PGCGs during the study. The mean age was 28.91 ± 18.16. PGCGs and CGCGs had a peak of occurrence in the first and second decade of life respectively. A female predominance was shown in CGCG cases (57.70%), whereas PGCGs were more frequent in males (50.85%). Five hundred and ninety-eight cases of all giant cell lesions (58.7 %) occurred in the mandible. Posterior mandible was the most frequent site for both CGCG and PGCG cases. The second most common site for PGCG was posterior maxilla (21%), whereas anterior mandible was involved in CGCG (19.45%). The majority of patients were asymptomatic. Conclusions: In contrast to most of previous studies PGCGs occur more common in the first decade and also more frequently in male patients. Although the CGCGs share some histopathologic similarities with PGCGs, differences in demographic features may be observed in different populations which may help in the diagnosis and management of these lesions.Bangladesh Journal of Medical Science Vol.15(2) 2016 p.220-223

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