Effectiveness and Appropriateness of mHealth Interventions for Maternal and Child Health: Systematic Review (Preprint)

BACKGROUND The application of mobile health (mHealth) technology in reproductive, maternal, newborn, and child health (RMNCH) is increasing worldwide. However, best practice and the most effective mHealth interventions have not been reviewed systematically. OBJECTIVE A systematic review and meta-analysis of studies of mHealth interventions for RMNCH around the world were conducted to investigate their characteristics as well as the features and effectiveness of mHealth interventions. METHODS Studies of mHealth interventions for RMNCH between January 2011 and December 2016 were retrieved from 6 databases (PubMed, EMBASE, Global Health, China National Knowledge Infrastructure, VIP Database for Chinese Technical Periodicals, and Wanfang Data Knowledge Service Medium). Comparable studies were included in a random-effects meta-analysis for both exclusive breastfeeding (EBF) and antenatal checks (ANC). Descriptive analyses were conducted for mHealth studies with a range of study designs. RESULTS Analyses of 245 studies were included, including 51 randomized controlled trials (RCTs). Results showed that there are increasing numbers of studies on mHealth interventions for RMNCH. Although 2 meta-analysis, one with 2 RCTs on EBF (odds ratio [OR] 2.03, 95% CI 1.34-3.08, I2=25%) and the other with 3 RCTs on ANC (OR 1.43, 95% CI 1.13-1.79, I2=78%), showed that mHealth interventions are more effective than usual care, almost half (43%) of RCTs showed negative or unclear results on mHealth interventions. Functions described in mHealth interventions were diverse, and the health stages covered were broad. However, single function or single stage appeared to be dominant among mHealth interventions compared with multiple functions or stages. CONCLUSIONS More rigorous evaluations are needed to draw consistent conclusions and to analyze mHealth products with multiple functions, especially those popular in the app markets.

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Faculty Opinions recommendation of Integrating antiretroviral therapy into antenatal care and maternal and child health settings: a systematic review and meta-analysis.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717977253.793470308 ◽

2013 ◽

Author(s):

Anthony Harries

Keyword(s):

Systematic Review ◽

Antiretroviral Therapy ◽

Child Health ◽

Antenatal Care ◽

Maternal And Child Health ◽

Meta Analysis ◽

And Child Health

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Effect of somatometric parameters on the prevalence and severity of varicocele: a systematic review and meta-analysis

Reproductive Biology and Endocrinology ◽

10.1186/s12958-021-00695-3 ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Runqing Li ◽

Junjie Liu ◽

Yushan Li ◽

Quanxian Wang

Keyword(s):

Systematic Review ◽

Meta Analysis ◽

Cochrane Library ◽

China National Knowledge Infrastructure ◽

Random Effects Models ◽

Knowledge Infrastructure ◽

Regression Test ◽

Mean Differences ◽

Q Statistic ◽

The Relationship

Abstract Background Published studies have shown contradictory results regarding the relationship between somatometric parameters and varicoceles. We performed a systematic review and meta-analysis to investigate the possible effects of age, height, weight, and body mass index (BMI) on the presence and severity of varicoceles. Methods Databases including EMBASE, MEDLINE, PubMed, Cochrane Library, China National Knowledge Infrastructure (CNKI), Web of Science, and Google Scholar were systematically searched to identify relevant articles published up to March 2020. Two researchers independently identified eligible articles and extracted data. Cochran’s Q statistic and I2 statistics were used to assess heterogeneity. Meta-analysis was performed using StataSE 12.0 software (StataCorp LP, USA). Random-effects models were used to obtain the weighted mean differences (WMDs) and 95% confidence intervals (CIs). Publication bias was assessed using Begg’s funnel plot and Egger’s regression test. Results The search strategy produced 272 articles, of which 18 articles were eligible according to the inclusion/exclusion criteria. A total of 56,325 patients with varicocele and 1,334,694 patients without varicocele were included in the meta-analysis to evaluate the effect of somatometric parameters on the presence and severity of varicocele. The overall results demonstrated that the presence of varicoceles was significantly associated with height (WMD = 1.41, 95% CI = 1.07 to 1.74, P < 0.001) and inversely correlated with BMI (WMD = − 1.35, 95% CI = -1.67 to − 1.03, P < 0.001) but not with age (WMD = -0.93, 95% CI = -2.19 to 0.33, P = 0.149) or weight (WMD = 0.24, 95% CI = -2.24 to 2.72, P = 0.850). The severity of varicocele was inversely correlated with increased BMI but not with age. Conclusion The presence of varicoceles was significantly associated with height and inversely correlated with BMI.

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Financial Incentives to Increase Utilization of Reproductive, Maternal, and Child Health Services in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

10.1596/1813-9450-9793 ◽

2021 ◽

Author(s):

Sven Neelsen ◽

Damien de Walque ◽

Jed Friedman ◽

Adam Wagstaff

Keyword(s):

Systematic Review ◽

Child Health ◽

Health Services ◽

Maternal And Child Health ◽

Financial Incentives ◽

Meta Analysis ◽

Child Health Services ◽

Middle Income ◽

Middle Income Countries ◽

And Child Health

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Effectiveness of interventions to reduce household air pollution from solid biomass fuels and improve maternal and child health outcomes in low‐ and middle‐income countries: A systematic review and meta‐analysis

Indoor Air ◽

10.1111/ina.12958 ◽

2022 ◽

Author(s):

Katherine E. Woolley ◽

Emma Dickinson‐Craig ◽

Heidi L. Lawson ◽

Jameela Sheikh ◽

Rosie Day ◽

...

Keyword(s):

Systematic Review ◽

Air Pollution ◽

Child Health ◽

Health Outcomes ◽

Meta Analysis ◽

Middle Income ◽

Middle Income Countries ◽

Child Health Outcomes ◽

Solid Biomass ◽

And Child Health

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Comparative efficacy of traditional non-selective NSAIDs and selective cyclo-oxygenase-2 inhibitors in patients with acute gout: a systematic review and meta-analysis

BMJ Open ◽

10.1136/bmjopen-2019-036748 ◽

2020 ◽

Vol 10 (9) ◽

pp. e036748

Author(s):

Mengtao Li ◽

Chen Yu ◽

Xiaofeng Zeng

Keyword(s):

Systematic Review ◽

Global Assessment ◽

Meta Analysis ◽

Likert Scale ◽

Acute Gout ◽

Comparative Efficacy ◽

China National Knowledge Infrastructure ◽

Vas Score ◽

Knowledge Infrastructure ◽

Randomised Controlled

ObjectiveTo assess the comparative efficacy of traditional non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclo-oxygenase-2 inhibitors in patients with acute gout.DesignSystematic review and meta-analysis.Data sourcesMedline, Web of Science, China National Knowledge Infrastructure and Wanfang Data published as of 4 April 2020.MethodsWe performed meta-analysis of randomised controlled trials (RCTs) of traditional non-selective NSAIDs versus cyclo-oxygenase-2 inhibitors and RCTs of various cyclo-oxygenase-2 inhibitors in patients with acute gout. The main outcome measures were mean change in pain Visual Analogue Scale (VAS) score and 5-point Likert scale score on days 2–8.ResultsTwenty-four trials involving five drugs were evaluated. For pain Likert scale, etoricoxib was comparable to indomethacin (standardised mean difference (SMD): −0.09, 95% CI: −0.27 to 0.08) but better than diclofenac 50 mg three times a day (SMD: −0.53, 95% CI: −0.98 to 0.09). Regarding pain VAS score, etoricoxib was comparable to diclofenac 75 mg two times per day (SMD: −1.63, 95% CI: −4.60 to 1.34) and diclofenac 75 mg four times a day (SMD: −1.82, 95% CI: −5.18 to 1.53), while celecoxib was comparable to diclofenac 100 mg four times a day (SMD: −2.41, 95% CI: −5.91 to 1.09). Etoricoxib showed similar patients’ global assessment of response (SMD: −0.10, 95% CI: −0.27 to 0.07) and swollen joint count (SMD: −0.25, 95% CI: −0.74 to 0.24), but better investigator’s global assessment of response (SMD: −0.29, 95% CI: −0.46 to 0.11) compared with indomethacin. Etoricoxib showed more favourable pain VAS score than celecoxib (SMD: −2.36, 95% CI: −3.36 to 1.37), but was comparable to meloxicam (SMD: −4.02, 95% CI: −10.28 to 2.24). Etoricoxib showed more favourable pain Likert scale than meloxicam (SMD: −0.56, 95% CI: −1.10 to 0.02). Etoricoxib 120 mg four times a day was more likely to achieve clinical improvement than celecoxib 200 mg two times per day (OR: 4.84, 95% CI: 2.19 to 10.72).ConclusionAlthough cyclo-oxygenase-2 inhibitors and traditional non-selective NSAIDs may be equally beneficial in terms of pain relief, cyclo-oxygenase-2 inhibitors (especially etoricoxib) may confer a greater benefit.

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